Yury Verlinsky and Anver Kuliev (eds) Atlas of preimplantation genetic diagnosis, 2nd edition. Taylor & Francis, ISBN 1-842-14245-3, hardcover

Extensively illustrated, this atlas is a manual for the establishment and realization of PGD within the framework of assisted reproduction and genetics services. Fully revised and updated, the atlas includes descriptions of the authors' pioneering work on polar body based PGD for genetic and chromosomal disorders. The authors' novel experience of PGD for late-onset disorders with genetic predisposition will be of special interest. Their accumulated PGD experience for poor-prognosis IVF patients presents further evidence of the improvement of clinical outcome and the requirement for meiotic error testing for a higher accuracy of preselecting aneuploidy-free embryos for transfer. "Preimplantation genetic diagnosis (PGD) - the detection of incipient disease in embryos prior to implantation in the womb - is a fast-growing and complex field of research that is rapidly entering everyday clinical practice. This extensively illustrated atlas provides a detailed manual for the establishment and realization of PGD within the framework of assisted reproduction and genetics services. This fully revised and updated volume presents knowledge based on the world's largest PGD experience of more than 2000 cycles performed for 100 different genetic conditions." "The illustrations from the first edition, clearly demonstrating the full range of techniques for PGD, have been supplemented with more than 100 unique new images including preimplantation diagnosis for aneuploidies, translocations and single-gene disorders. This makes the book of practical usefulness for reproductive medicine and genetics practices, and an invaluable aid for all those involved in human reproduction."--BOOK JACKET Prevention of the birth of affected children in couples at genetic risk is currently based on population screening and prenatal diagnosis, followed by termination of affected pregnancies.