World Congress on Medical Physics and Biomedical Engineering 2018: June 3-8, 2018, Prague, Czech Republic (Vol.1) (IFMBE Proceedings, 68/1)

Preface Organizing Committees Congress Coordinating Committee Congress Organizing Committee Financial Committee Scientific Committee Program Committee Publicity Committee Education Committee Professional Standards Committee Publication Committee International Advisory Board (BME) International Advisory Board (MP) Organizing Societies International Societies Collaborating Institution Sponsors About IFMBEThe International Federation for Medical and Biological Engineering (IFMBE) is primarily a federation of national and transnational societies. These professional organizations represent interests in medical and biological engineering. IFMBE is also a non-governmental organization (NGO) for the United Nations and the World Health Organization (WHO), where we are uniquely positioned to influence the delivery of health care to the world through biomedical and clinical engineering.The IFMBE’s objectives are scientific and technological as well as educational and literary. Within the field of medical, biological, and clinical engineering, IFMBE’s aims are to encourage research and application of knowledge and to disseminate information and promote collaboration. The ways in which we disseminate information include the following: organizing World Congresses and Regional Conferences, publishing our flagship journal Medical and Biological Engineering and Computing (MBEC), our Web-based newsletter—IFMBE News, our Congress and Conference Proceedings, and books. The ways in which we promote collaborations are through networking programs, workshops, and partnerships with other professional groups, e.g., Engineering World Health.MissionThe mission of IFMBE is to encourage, support, represent, and unify the worldwide medical and biological engineering community in order to promote health and quality of life through the advancement of research, development, application, and management of technology.ObjectivesThe objectives of the International Federation for Medical and Biological Engineering shall be scientific, technological, literary, and educational. Within the field of medical, clinical, and biological engineering, its aims shall be to encourage research and the application of knowledge and to disseminate information and promote collaboration.In pursuit of these aims, the Federation may, in relation to its specific field of interest, engage in any of the following activities: sponsorship of national and international meetings, publication of official journals, cooperation with other societies and organizations, appointment of commissions on special problems, awarding of prizes and distinctions, establishment of professional standards and ethics within the field, or in any other activities which in the opinion of the General Assembly or the Administrative Council would further the cause of medical, clinical, or biological engineering. It may promote the formation of regional, national, international, or specialized societies, groups or boards, the coordination of bibliographic or informational services, and the improvement of standards in terminology, equipment, methods and safety practices, and the delivery of health care.In general, the Federation shall work to promote improved communication and understanding in the world community of engineering, medicine, and biology. Contents Diagnostic Imaging 1 Fast In Vivo High-Resolution Diffusion MRI of the Human Cervical Spinal Cord Microstructure Abstract 1 Introduction 2 Materials and Methods 2.1 Data Acquisition Protocols 2.2 Data Processing and Registration 3 Results 4 Discussion 4.1 Contributions 4.2 Limitations and Future Work Acknowledgements References 2 Image Quality Evaluation of Phase Contrast Mammographic Techniques Abstract 1 Introduction 2 Materials and Methods 2.1 Hardware Phantom 2.2 Image Acquisition 2.3 Evaluation Metrics 3 Results 4 Discussion and Conclusion References 3 Thermography Evaluation in Patients with Hypothyroidism and Fibromyalgia by Analyzing the Temperatures of the Palms of Hands Abstract 1 Introduction 2 Methods 3 Results 4 Discussion 5 Conclusion Conflict of Interest Statement References 4 Material Analysis for a New Kind of Hybrid Phantoms Utilized in Multimodal Imaging Abstract 1 Introduction 2 Materials and Methods 2.1 Composition of the Material Samples 2.2 Sample Preparation 2.3 MR-Relaxometry (T1- and T2-Measurements) 2.4 X-Ray Absorption (CT and SPECT-Measurements) 3 Results 3.1 General Properties of the Material Samples 3.2 MR-Relaxometry (T1- and T2-Measurements) 3.3 X-Ray Absorption (HU-Measurements) and Attenuation in Nuculear Medicine 4 Discussion 5 Conclusion Compliance with Ethical Standards Electronic Supplementary Material References 5 Basic Study of the Imaging Conditions on Tumor Volume Measurement Using 3D-MR Imaging of the Liver While Patient Holds Breath Abstract 1 Introduction 2 Materials and Methods 3 Results 4 Discussion 5 Conclusion References 6 Evaluation of Spatial Resolution of MRI, Optical CT and X-Ray CT Using MTF for Gel Dosimeter Abstract 1 Introduction 2 Materials and Methods 2.1 Gelatin Phantom 2.2 Measurement 3 Results and Discussion References 7 Local Affine Transformation Method for Tomosynthesis Abstract 1 Introduction 2 A Description of the Proposed Tomosynthesis Technique 3 Conclusion References 8 Size and Shape of Spherical Objects on Full-Field Digital Mammography and Digital Breast Tomosynthesis Images Abstract 1 Introduction 2 Materials and Methods 3 Results 4 Discussion 5 Conclusion Disclosures of Conflicts of Interest References 9 Training Towards Precise Control Over Muscle Activity with Real Time Biofeedback Based on Ultrasound Imaging Abstract 1 Introduction 2 Materials and Methods 2.1 Participants and Measurement Procedure 2.2 Analysis Methods 3 Results 4 Discussion and Conclusions Conflict of Interest References 10 On the CT Dose Index: Are we Meeting the Challenge? Abstract 1 Introduction 2 Methods 3 Results and Discussion 4 Conclusions Conflict of Interest References 11 Comparative Sequence Assessment of Optimised T2 and T2* Sequences for Quantification of Iron in Transfused Dependent Paediatric Sickle Cell Anaemia (SCA) Patients Abstract 1 Introduction 2 Materials and Method 2.1 Study Population 2.2 Serum Ferritin 2.3 Magnetic Resonance Imaging 2.4 Image Resolution Index 3 Results and Discussion 4 Conclusion Conflict of Interest References 12 Quantitative Performance Evaluation of Mobile Cone-Beam CT for Head and Neck Imaging Abstract 1 Introduction 2 Materials and Methods 2.1 The Proposed Mobile CBCT 2.2 Radiation Dose 2.3 Image Quality 3 Results 4 Conclusions References 13 Prediction of Alzheimer’s Disease in Mild Cognitive Impairment Using Sulcal Morphology and Cortical Thickness Abstract 1 Introduction 2 Methods 2.1 Data 2.2 Feature Extraction, Selection and Classification 3 Results 4 Discussion Conflict of Interest References 14 Effect of Elimination of Noisy ECG Leads on the Noninvasive Localization of the Focus of Premature Ventricular Complexes Abstract 1 Introduction 2 Materials and Methods 2.1 Body Surface Potential Mapping 2.2 Computed Tomography 2.3 Electrophysiological Study 2.4 Inverse Solution 2.5 Evaluation of the Inverse Solution 3 Results 4 Conclusion Conflict of interest References 15 Effect of Electrode Gel Application Between Patient’s Skin and Electrode Belt on Electrical Impedance Tomography of the Thorax Abstract 1 Introduction 2 Methods 2.1 Minimizing the Factors Influencing EIT Signal 2.2 Set of Pilot Measurements 2.3 Data Analysis 3 Results 4 Discussion 5 Conclusion Conflict of Interest Declaration References 16 Capsaicin Effects on Human Facial and Neck Temperature Abstract 1 Introduction 1.1 Function of Capsaicin in Human Body 2 Methods 2.1 Infrared Thermography in Medicine 2.2 Facial and Neck Temperature Measurement 3 Results 3.1 Infrared Thermography 4 Conclusion Conflict of Interest Declaration References 17 Assessment of Brain Water Content in Peripheral Inflammation by an Optimized Single-Voxel MR Spectroscopy Quantitation Technique Abstract 1 Introduction 2 Methods 2.1 Subjects 2.2 MRI/MRS Acquisition 2.3 Correction Factors in the Calibration of the In Vivo Water Signal Against Aphan 2.4 Spectral Analysis 2.5 Quantification of Brain Tissue Water Content (BWC) 2.6 Statistical Analysis 3 Results 3.1 In Vitro Experiments 3.2 In Vivo Experiments 4 Discussion 5 Conclusions Conflict of Interest References 18 Noninvasive Imaging of the Origin of Premature Ventricular Activity Abstract 1 Introduction 2 Materials and Methods 2.1 ECG Measurement and CT Scanning 2.2 Noninvasive Localization of the PVC Origin 2.3 The EPS and the Ablation Procedure 2.4 Evaluation of the Noninvasive Localization of the PVC Origin 3 Results 4 Discussion and Conclusions Conflict of Interest References 19 Quantitative Assessment of Strabismus and Selected Vision Related Anomalies Abstract 1 Introduction 2 Strabismus Analysis Procedure 2.1 Data Collection 2.2 Image Processing 2.3 Estimation of Deviation 2.4 Graphical User Interface 3 Prediction and Results 4 Conclusion Conflict of Interest References 20 Phase-Contrast Breast-CT: Optimization of Experimental Parameters and Reconstruction Algorithms Abstract 1 Introduction 2 Materials and Methods 2.1 Breast Tissue Sample 2.2 Experimental Setup and Acquisition Parameters 2.3 Data Pre-processing and Reconstruction 2.4 Quantitative Analysis 3 Results and Discussion 4 Conclusions Acknowledgements Compliance with Ethical Requirements References 21 Response of CR Detector Plates for Use in Mammography Equipment Abstract 1 Introduction 2 Methodology 2.1 Mammographic System 2.2 Caracterización de la respuesta de la placa CR y dosimetría 3 Results 4 Conclusions Acknowledgements References 22 Towards In Vivo K-Edge X-Ray Micro-CT with the Pixirad-I/Pixie-III Detector Abstract 1 Introduction 2 Materials and Methods 2.1 Hardware Setup 2.2 Test Object 2.3 Acquisitions 2.4 Image Processing and Reconstruction 3 Results and Discussion 4 Conclusion Conflicts of Interest References Image Processing 23 Diffusion and Perfusion MR Parameters in Locally Advanced Rectal Cancer Management: An Explorative Study Abstract 1 Introduction 2 Methods 2.1 Patients 2.2 Specimens Evaluation 2.3 Imaging 2.3.1 Diffusion weighted MRI 2.3.2 Dynamic Contrast Enhanced MRI 2.4 Feature Extraction 2.4.1 IVIM Parameters 2.4.2 Diffusion kurtosis Parameters 2.4.3 Standard Index of Shape 2.5 Statistical Analysis 2.5.1 Mono-parameter Analysis 2.5.2 Multi-parametric Analysis 3 Results 4 Discussion Conflict of Interest References 24 Mammographic Density Estimation Through Permutation Entropy Abstract 1 Introduction 2 Materials and Methods 2.1 BI-RADS Classification and Breast Density 2.2 Permutation Entropy (PE) for Temporal Series and Images 2.3 Image Database 2.4 Proposed Descriptors 2.5 Density Classifier 3 Results and Discussion 4 Conclusion Conflicts of Interest References 25 Multiregional Radiomics Phenotypes at MR Imaging Predict MGMT Promoter Methylation in Glioblastoma Abstract 1 Introduction 2 Materials and Methods 2.1 Study Cohort 2.2 Image Preprocessing and Tumor Subregions Segmentation 2.3 Multiregional MRI Radiomics Feature Extraction 2.4 Feature Selection and Classification Model 2.5 Statistical Analysis 3 Results and Discussions 4 Conclusions Conflict of Interest References 26 Influence of Image Resolution Property on Aliasing Error of Digital Wiener Spectrum Abstract 1 Introduction 2 Materials and Methods 2.1 Image Simulation 2.2 WS Analysis 2.3 Theoretical WS 3 Results 4 Discussion 5 Conclusion Conflict of interest References 27 Automatic Identification and Extraction of Pectoral Muscle in Digital Mammography Abstract 1 Introduction 2 Methodology 2.1 Dataset 2.2 Developed Algorithm 2.3 Validation 3 Results and Discussion 4 Conclusion Conflict of Interest Statement References 28 Fully Automatic CAD System for Segmentation and Classification of Spinal Metastatic Lesions in CT Data Abstract 1 Introduction 2 Materials and Methods 2.1 Used Dataset 2.2 Data Pre-processing 2.3 Convolutional Neural Network—Architecture and Learning 3 Results and Discussion 4 Conclusion Conflict of Interest References 29 A Classification and Segmentation Combined Two-Stage CNN Model for Automatic Segmentation of Brainstem Abstract 1 Introduction 2 Method 2.1 The Classification-CNN 2.2 The Segmentation-CNN 2.3 The Segmentation-CNN Loss Function 3 Experiments and Results 3.1 Training Details 3.2 Accuracy and Running Time 4 Conclusion Acknowledgements References 30 Biometrics Based on Facial Landmark with Application in Person Identification Abstract 1 Introduction 2 Facial Biometrics Based on Facial Landmarks Extraction 3 Affine Transformation and Image Registration 4 Person Identification 5 Experimental and Result 6 Conclusion References 31 A Computational Tool for Enhancing Ischemic Stroke in Computed Tomography Examinations Abstract 1 Introduction 2 Methods 2.1 Patients and Image Selection 2.2 Developed Approach 2.3 Segmentation Methods 2.4 Observers Evaluation 3 Results 4 Discussion and Conclusion References 32 Improving Priors for USTC via Transmission Tomography: A Simulation Study Abstract 1 Introduction 2 Transmission Algorithms and Filters 3 Method 3.1 Model Generation 3.2 Simulation 3.3 Simultaneous Algebraic Reconstruction Technique and m-MMF 4 Results 5 Discussion and Conclusions Conflict of Interest Declaration References 33 Brain Tumor Classification Using Convolutional Neural Network Abstract 1 Introduction 2 Previous Work 3 Method 3.1 Convolutional Neural Network 3.2 CNN Architecture 3.3 Hyper-parameters Optimization 4 Data 5 Result 6 Conclusion Disclosure References 34 A Novel Method for 3D Reconstruction of Coronary Bifurcation Using Quantitative Coronary Angiography Abstract 1 Introduction 1.1 A Subsection Sample 2 Materials and Methods 2.1 Data Acquisition 2.2 Vessel Segmentation and 2D Centerline Extraction 2.3 Centerline and Lumen Borders 3D Reconstruction 2.4 Registration of the Main and the Side Branch 2.5 Evaluation Methodology 3 Results 4 Discussion 5 Conclusions Conflict of Interest References 35 Machine Learning Techniques for Classification of Breast Cancer Abstract 1 Introduction 2 Methods 3 Results and Discussion 4 Conclusion Declaration of Interest References 36 Segmentation and 3D-Modelling of Single-Rooted Teeth from CBCT Data: An Automatic Strategy Based on Dental Pulp Segmentation and Surface Deformation Abstract 1 Introduction 2 Methods 2.1 Volume Partitioning 2.2 Three-Dimensional Segmentation 3 Results and Discussion 4 Conclusion Conflict of Interest References 37 A Three-Dimensional Quantification of Calcified and Non-calcified Plaque Based on Computed Tomography Coronary Angiography Images: Comparison with Virtual Histology Intravascular Ultrasound Abstract 1 Introduction 2 Materials and Methods 2.1 Preprocessing 2.2 Blooming Effect Removal 2.3 Centerline Extraction 2.4 Estimation of Memberships Functions 2.5 Segmentation of the Lumen, the Outer Wall and CP 2.6 NCP Segmentation 2.7 3D Models Construction 3 CTCA-IVUS Comparison 4 Results 5 Discussion 6 Conclusions Acknowledgements References 38 Creation of Computational Breast Phantoms with Extracted Abnormalities from Real Patient Images Abstract 1 Introduction 2 Materials and Methods 2.1 Clinical Data 2.2 Breast Simulator 2.3 Segmentation Algorithm 2.4 Insertion of Extracted Abnormalities into Computational Breast Phantoms 3 Results and Discussions 3.1 Phantoms 3.2 Segmented Models 3.3 Computational Breast Phantoms with Extracted Abnormalities 4 Conclusions Conflict of Interest References 39 Metal Artifact Reduction by Morphological Image Filtering for Computed Tomography Abstract 1 Introduction 2 Materials and Methods 2.1 Metal Artifact Reduction Approaches 2.2 Morphologically Image Filtering 2.3 Patients 2.4 Evaluation and Statistical Analysis 3 Results 4 Discussion 5 Conclusions Conflict of Interest References 40 Fully Automatic CAD System for Spine Localisation and Vertebra Segmentation in CT Data Abstract 1 Introduction 2 Methodology 3 Results and Discussion 3.1 Our Database 3.2 Publicly Available Datasets 4 Conclusion Conflict of Interest References 41 Hyperdense Middle Cerebral Artery Segmentation in Non Contrast Computed Tomography Abstract 1 Introduction 2 Methodology 2.1 Preprocessing 2.2 Region of Interest 2.3 Feature Extraction 2.4 Segmentation 2.5 Validation 3 Results and Discussion 4 Conclusions References 42 Joint Adaptive Beamforming to Enhance Noise Suppression for Medical Ultrasound Imaging Abstract 1 Introduction 2 Beamformers 3 Proposed Method 4 Results and Discussion 5 Conclusion References 43 Label-Free Nuclear Staining Reconstruction in Quantitative Phase Images Using Deep Learning Abstract 1 Introduction 2 Materials and Methods 2.1 Experimental Data 2.2 Used Models 2.3 Preprocessing 2.4 Network Implementation 2.5 Nucleus Segmentation 3 Results 4 Discussion 5 Conclusions Conflict of Interest References 44 Performance Comparison of Segmentation Algorithms for Image Quality Degraded MR Images Abstract 1 Introduction 2 Methodology 2.1 JPEG Compression Algorithm 2.2 Intracranial Area, White Matter and Gray Matter Segmentation 3 Results 4 Conclusion Conflict of Interest References 45 Application of Low-Cost 3D Printing for Production of CT-Based Individual Surgery Supplies Abstract 1 Introduction 2 Introduction 2.1 Research Problem 2.2 Methodology of Design and Rapid Manufacturing of Medical Products 2.3 The Fused Deposition Modelling Technology 2.4 Mandibular Reconstruction Template—Case Description 2.5 Course of Studies 3 Results 4 Discussion 5 Conclusions Conflict of Interest References 46 Examination of the Spatial Structure of Pigs’ Melanoma in Tissue Sections Based on Histology and Mass Spectrometry Abstract 1 Introduction 2 Methods 2.1 Data Collection 2.2 Data Integration 2.3 Clustering 2.4 Statistical Analysis 3 Results 3.1 Data Integration 3.2 Clustering 4 Conclusion Acknowledgements References 47 Automatic Characterization of Plaques and Tissue in IVOCT Images Using a Multi-step Convolutional Neural Network Framework Abstract 1 Introduction 2 Methods 2.1 Materials 2.2 Patches Analysis 2.3 Classification of Plaques—Transfer Learning 2.4 Multi-step Processing 3 Results 4 Discussion 5 Conclusion Conflict of interest References 48 Iterative Methods for Fast Reconstruction of Undersampled Dynamic Contrast-Enhanced MRI Data Abstract 1 Introduction 2 Models 2.1 TV Regularization with Pre-estimated Temporal Basis 2.2 Low-Rank Plus Sparse (L + S) 2.3 ICTGV Model 3 Data Acquisition and Evaluation Methods 4 Results and Discussion 5 Conclusions Conflict of Interest References 49 Multimodality Image Fusion of the Liver Using Structure-Guided Deformable Image Registration in Velocity AI—What Is the Preferred Approach? Abstract 1 Introduction 2 Materials and Methods 2.1 Structure Segmentation 2.2 Deformable Image Registration 3 Results 4 Discussion 5 Conclusion Conflict of Interest References 50 First Validation of Semi-automatic Liver Segmentation Algorithm Abstract 1 Introduction 2 Methods 3 Results 4 Discussion 5 Conclusion Conflict of Interest References 51 Image Quality Optimization and Soft Tissue Visualization in Cone-Beam CT Imaging Abstract 1 Introduction 2 Materials and Methods 2.1 Attenuation Physics 2.2 Experiments 3 Results 3.1 Water Phantom 3.2 Wedge Phantom 4 Discussion and Conclusions Conflicts of Interest References 52 A Method to Detect Potentially Malignant Skin Lesions Through Image Segmentation Abstract 1 Introduction 2 Materials and Methods 2.1 Region of Interest 2.2 Asymmetry Criterion from ABCDE Rule for Melanoma Detection 2.3 Border Criterion from ABCDE Rule for Melanoma Detection 2.4 Colour Variation Criterion from ABCDE Rule for Melanoma Detection 2.5 Texture Parameter for Melanoma Diagnosis 3 Results 4 Discussion and Conclusion Conflict of Interest References Information Technology in Healthcare 53 A Gait Character Analyzing System for Osteoarthritis Pre-diagnosis Using RGB-D Camera and Supervised Classifier Abstract 1 Introduction 2 Materials and Methods 2.1 Gait Data Acquisition and Analysis 2.2 Gait Features and Classifier 3 Results 3.1 Experimental Set up 3.2 Calculating Parameters 3.3 Classification for OA Patients 4 Discussion and Conclusion Conflict of Interest References 54 Architecture and Organization of a Computational System for the Management of Data from Individuals with Parkinson’s Disease Abstract 1 Introduction 2 Materials and Methods 2.1 Model-View-Controller Architecture and Development Environment 3 Results 4 Discussion and Conclusion Conflicts of Interest References 55 Developing an Automated Clinical Trending Tool for the Neonatal Intensive Care Unit (NICU) Abstract 1 Introduction 2 Methodology 2.1 Displaying the Heart Rate Data 2.2 Using a Filter 2.3 Displaying the Oxygen Saturation Data 2.4 Visualization Tools 3 Results and Discussions 4 Conclusions Acknowledgements References 56 Data Analytics for Metabolic Syndrome Diagnostics Abstract 1 Introduction 2 CRISP-DM 2.1 Business Understanding 2.2 Data Understanding 2.3 Data Preparation 2.4 Modelling 2.5 Evaluation 3 Conclusion Conflicts of Interest References 57 Medical Expert System with the Properties of Artificial Intelligence Abstract 1 Introduction 2 Integrality and Meta Logic 3 Tolerance and Harmonization 4 Conclusions References 58 A Simple Room Localization Method to Find Technology in a Big Trauma Center Abstract 1 Introduction 1.1 Methods for Position Calculation 1.2 Methods for Reducing the Variability of Signals 2 Methods 2.1 Selected Methods for Study 3 Results and Discussion 4 Conclusions Conflict of Interest References 59 The Influence of the Voice Acquisition Method to the Mental Health State Estimation Based on Vocal Analysis Abstract 1 Introduction 2 Materials and Methods 2.1 Vocal Analysis 2.2 Beck’s Depression Inventory 2.3 Experiment 2.4 Analysis of Data 3 Results 3.1 Effect of the Recording Method 4 Discussion 5 Conclusion Conflict of Interest References 60 Using Artificial Neural Network to Predict Functional Recovery of Patients Treated by Intravenous Thrombolysis in Acute Ischemic Stroke Abstract 1 Introduction 2 Materials and Methods 2.1 Data Collection 2.2 ANN Model Construction and Evaluation 3 Results 4 Conclusions and Discussion References 61 Estimation of the Heart Rate Variability Features via Recurrent Neural Networks Abstract 1 Introduction 1.1 Related Work 2 Methods 2.1 Dataset Description 2.2 ECG Preprocessing 2.3 LSTM Architecture for the ECG Analysis 2.4 Training and Evaluation 3 Results 4 Discussion Conflict of Interest References 62 Study on Non-contact Heart Beat Measurement Method by Using Depth Sensor Abstract 1 Introduction 2 Method 2.1 System Configuration 2.2 Detection of Heart Beat 3 Experiment and Result 4 Conclusion Acknowledgements References 63 Design Reflection on Mobile Electronic Data Capturing Forms in African Rural Settings Abstract 1 Introduction 2 Method 3 Results 4 Discussion 5 Conclusion Conflict of Interest References 64 Evaluation Methodology and Measurement of Physiological Data to Determine Operational Preparedness of Air Defense Staff: Preliminary Results Abstract 1 Introduction 2 Methods 2.1 Participants 2.2 Measurement Equipment 2.3 Test Procedure 2.4 Data Processing 3 Results 4 Discussion 5 Conclusion Conflict of Interest References 65 A Multiple Criteria Decision Making System for Setting Priorities Abstract 1 Introduction 2 Materials and Methods 3 Results 3.1 AOGrupo 3.2 An Application of AOGrupo in a Real Scenario 4 Discussion Conflicts of Interest References 66 Towards Computer Supported Search for Semiological Features in Epilepsy Seizure Classification Abstract 1 Introduction 2 ASTEP: Annotation and Statistical Tool for EPilepsy 3 User Experience and Preliminary Results 4 Conclusions Acknowledgements References 67 Scoring System for the One-Year Mortality Prediction of Sepsis Patients in Intensive Care Units Abstract 1 Introduction 2 Methods 2.1 Data Description 2.2 Score Development 3 Results 4 Conclusions Conflicts of Interest References 68 Computerized Cognitive Assessment System for Dementia Screening Application Abstract 1 Introduction 1.1 Background 1.2 Cognitive Assessments 1.3 Computerization 1.4 Serious Game 2 Materials and Methods 2.1 Computerized Cognitive Assessment System 2.2 Subject Information 2.3 Experimental Design 2.4 Questionnaire 3 Results and Discussion 3.1 Results 3.2 Discussion 4 Conclusion References 69 Modeling Biological Data Through Dynamic Bayesian Networks for Oral Squamous Cell Carcinoma Classification Abstract 1 Introduction 2 Materials and Methods 2.1 Transcriptomic Dataset 2.2 Differentially Expressed Genes 2.3 Transcription Factors 2.4 Dynamic Bayesian Network Modeling 3 Results and Discussion 3.1 Differentially Expressed Genes 3.2 Transcription Factors 3.3 Modeling OSCC Through DBNs 4 Conclusions Conflicts of Interest References 70 A Process Modelling and Analytic Hierarchy Process Approach to Investigate the Potential of the IoT in Health Services Abstract 1 Introduction 2 Method 2.1 Process Modeling 2.2 Analytical Hierarchy Process 3 Results 4 Conclusions Conflicts of Interest References 71 A Virtual CPR (Cardio-Pulmonary Resuscitation) Learning System Using Motion Capture Device Abstract 1 CPR Training for Non-medical Persons 2 Hand Motion Capture Device for Simulator 3 CPR Training Scenarios 3.1 Reference AED Trainer 3.2 CPR Scenarios 4 Implementation of Virtual CPR Learning System 4.1 System Development Environment 4.2 Simulated Procedure of AED Usage 4.3 Tutorials 4.4 Simulated Procedure of Chest Compression 5 Usability Evaluation 6 Discussion Conflicts of Interest References 72 Usability of Electronic Patient Records for Assessment and Care Planning in Nursing Homes Abstract 1 Background 2 Research Objectives 3 Study Design and Methods of Data Collection and Analysis 3.1 Study Design 3.2 Data Collection 3.3 Sampling and Inclusion Criteria 3.4 Data Analysis 4 Ethical Issues 4.1 Assessment and Management of Risk 4.2 Consent 5 Impact of Results Conflicts of Interest References 73 Data Security and Raw Data Access of Contemporary Mobile Sensor Devices Abstract 1 Introduction 2 Materials 3 Methods 3.1 Data Access 3.2 Data Interpretation 3.3 Results 4 Conclusion 5 Outlook Conflict of Interest References 74 Security Mechanism for Medical Record Exchange Using Hippocratic Protocol Abstract 1 Introduction 2 Test Model Elements 2.1 Hardware 2.2 Server Software 2.3 Terminal Software 3 Test Performed 3.1 Hippocratic Characteristics 3.2 Time Response 3.3 Persistence of Data in the Terminal 4 Discussion 5 Conclusion Conflict of Interest References 75 An Engineering Module to Identify Potential Diabetes Patients and Preventive Measures for Diabetes in Developing Countries like Bangladesh Abstract 1 Background 2 Current Status of Diabetes in Southeast Asia 3 Diabetes Related Software Apps Survey 3.1 POWER2DM 3.2 MISSION-T2D 3.3 ProEmpower 4 Objectives 5 Methods and Related Works 6 Expected Outcomes 7 Conclusion Conflict of interest References 76 MULTISAB: A Web Platform for Analysis of Multivariate Heterogeneous Biomedical Time-Series Abstract 1 Introduction 2 The Processing Subproject Architecture 2.1 Implemented Frameworks 3 Analysis Scenario 4 Conclusion Conflict of interest References 77 Technologies Catalog to Support the Identification of User Behavior During Usability Tests Abstract 1 Introduction 2 Method 3 Study of Behavioral Categories 4 Technologies That Detect User Behavior 5 Conclusion References 78 t-SNE Applied to Discriminate Healthy Individuals from Those with Parkinson’s Disease Executing Motor Tasks Detected by Non-contact Capacitive Sensors Abstract 1 Introduction 2 Methods 2.1 Experimental Setup 2.2 Signal Preprocessing 2.3 Feature Extraction 2.4 Data Visualization 3 Results 3.1 Typical Waveforms 3.2 Feature Analysis 3.3 Data Visualization 4 Discussion and Conclusion Acknowledgements Conflicts of Interest References 79 Electronic Delivery Book: Structured Database Enables Analysis of Perinatal Risk Factors Abstract 1 Introduction 2 Electronic Delivery Book 3 Critical Factor Analysis 3.1 Data and Features 3.2 Statistic Evaluation 3.3 Results 4 Conclusion Acknowledgements Conflict of Interest References 80 Wearable Cardiorespiratory Monitoring System for Unobtrusive Free-Living Energy Expenditure Tracking Abstract 1 Introduction 2 System Architecture 3 Experiment 4 Results and Discussion 5 Conclusion Acknowledgements and Conflict of Interest References 81 Design Variations for Improved Usability of Mobile Data Capture in Rural Uganda Abstract 1 Introduction 2 Methods 3 Results 3.1 Individual Expert Review 3.2 Mid-Fidelity Prototypes 3.3 User Preference Testing 4 Discussion 5 Conclusion Conflict of Interest References 82 Advancing Medical Practice Through Computer Expert Systems Abstract 1 Introduction 2 Literature Review 2.1 Components of Expert Systems 2.2 Applications of Expert Systems 2.3 Medical Practice, Malaria, Developing Countries and Expert Systems 3 Methodology 4 Results and Discussion 5 Conclusion Conflict of Interest References 83 Propose a Model of Multimedia Electronic Patient Record System for Sri Lankan Public Health Sector Abstract 1 Introduction 2 Materials and Methods 3 Results and Discussion 4 Conclusion References 84 Multiple Sclerosis Application Design with Medical Expert Evaluation Abstract 1 Introduction 2 Method 3 Results 3.1 First Design Iteration 3.2 Second Design Iteration 4 Discussion 5 Conclusions Compliance with Ethical Standards References 85 Design Features for Usable Mobile Electronic Data Capturing Forms: The Form Developers’ Perspective Abstract 1 Introduction 2 Methods 3 Results 4 Discussion 5 Conclusion and Recommendation Ethics References 86 Task-Based Approach Recommendations to Enhance Data Visualization in the Kenya National Health Data Warehouse Abstract 1 Introduction 2 Methods 3 Results 3.1 Tasks: Distribution of EMRs and Patient Health Outcomes Preface Organizing Committees Congress Coordinating Committee Congress Organizing Committee Financial Committee Scientific Committee Program Committee Publicity Committee Education Committee Professional Standards Committee Publication Committee International Advisory Board (BME) International Advisory Board (MP) Organizing Societies International Societies Collaborating Institution Sponsors About IFMBEThe International Federation for Medical and Biological Engineering (IFMBE) is primarily a federation of national and transnational societies. These professional organizations represent interests in medical and biological engineering. IFMBE is also a non-governmental organization (NGO) for the United Nations and the World Health Organization (WHO), where we are uniquely positioned to influence the delivery of health care to the world through biomedical and clinical engineering.The IFMBE’s objectives are scientific and technological as well as educational and literary. Within the field of medical, biological, and clinical engineering, IFMBE’s aims are to encourage research and application of knowledge and to disseminate information and promote collaboration. The ways in which we disseminate information include the following: organizing World Congresses and Regional Conferences, publishing our flagship journal Medical and Biological Engineering and Computing (MBEC), our Web-based newsletter—IFMBE News, our Congress and Conference Proceedings, and books. The ways in which we promote collaborations are through networking programs, workshops, and partnerships with other professional groups, e.g., Engineering World Health.MissionThe mission of IFMBE is to encourage, support, represent, and unify the worldwide medical and biological engineering community in order to promote health and quality of life through the advancement of research, development, application, and management of technology.ObjectivesThe objectives of the International Federation for Medical and Biological Engineering shall be scientific, technological, literary, and educational. Within the field of medical, clinical, and biological engineering, its aims shall be to encourage research and the application of knowledge and to disseminate information and promote collaboration.In pursuit of these aims, the Federation may, in relation to its specific field of interest, engage in any of the following activities: sponsorship of national and international meetings, publication of official journals, cooperation with other societies and organizations, appointment of commissions on special problems, awarding of prizes and distinctions, establishment of professional standards and ethics within the field, or in any other activities which in the opinion of the General Assembly or the Administrative Council would further the cause of medical, clinical, or biological engineering. It may promote the formation of regional, national, international, or specialized societies, groups or boards, the coordination of bibliographic or informational services, and the improvement of standards in terminology, equipment, methods and safety practices, and the delivery of health care.In general, the Federation shall work to promote improved communication and understanding in the world community of engineering, medicine, and biology. Contents Diagnostic Imaging 1 Fast In Vivo High-Resolution Diffusion MRI of the Human Cervical Spinal Cord Microstructure Abstract 1 Introduction 2 Materials and Methods 2.1 Data Acquisition Protocols 2.2 Data Processing and Registration 3 Results 4 Discussion 4.1 Contributions 4.2 Limitations and Future Work Acknowledgements References 2 Image Quality Evaluation of Phase Contrast Mammographic Techniques Abstract 1 Introduction 2 Materials and Methods 2.1 Hardware Phantom 2.2 Image Acquisition 2.3 Evaluation Metrics 3 Results 4 Discussion and Conclusion References 3 Thermography Evaluation in Patients with Hypothyroidism and Fibromyalgia by Analyzing the Temperatures of the Palms of Hands Abstract 1 Introduction 2 Methods 3 Results 4 Discussion 5 Conclusion Conflict of Interest Statement References 4 Material Analysis for a New Kind of Hybrid Phantoms Utilized in Multimodal Imaging Abstract 1 Introduction 2 Materials and Methods 2.1 Composition of the Material Samples 2.2 Sample Preparation 2.3 MR-Relaxometry (T1- and T2-Measurements) 2.4 X-Ray Absorption (CT and SPECT-Measurements) 3 Results 3.1 General Properties of the Material Samples 3.2 MR-Relaxometry (T1- and T2-Measurements) 3.3 X-Ray Absorption (HU-Measurements) and Attenuation in Nuculear Medicine 4 Discussion 5 Conclusion Compliance with Ethical Standards Electronic Supplementary Material References 5 Basic Study of the Imaging Conditions on Tumor Volume Measurement Using 3D-MR Imaging of the Liver While Patient Holds Breath Abstract 1 Introduction 2 Materials and Methods 3 Results 4 Discussion 5 Conclusion References 6 Evaluation of Spatial Resolution of MRI, Optical CT and X-Ray CT Using MTF for Gel Dosimeter Abstract 1 Introduction 2 Materials and Methods 2.1 Gelatin Phantom 2.2 Measurement 3 Results and Discussion References 7 Local Affine Transformation Method for Tomosynthesis Abstract 1 Introduction 2 A Description of the Proposed Tomosynthesis Technique 3 Conclusion References 8 Size and Shape of Spherical Objects on Full-Field Digital Mammography and Digital Breast Tomosynthesis Images Abstract 1 Introduction 2 Materials and Methods 3 Results 4 Discussion 5 Conclusion Disclosures of Conflicts of Interest References 9 Training Towards Precise Control Over Muscle Activity with Real Time Biofeedback Based on Ultrasound Imaging Abstract 1 Introduction 2 Materials and Methods 2.1 Participants and Measurement Procedure 2.2 Analysis Methods 3 Results 4 Discussion and Conclusions Conflict of Interest References 10 On the CT Dose Index: Are we Meeting the Challenge? Abstract 1 Introduction 2 Methods 3 Results and Discussion 4 Conclusions Conflict of Interest References 11 Comparative Sequence Assessment of Optimised T2 and T2* Sequences for Quantification of Iron in Transfused Dependent Paediatric Sickle Cell Anaemia (SCA) Patients Abstract 1 Introduction 2 Materials and Method 2.1 Study Population 2.2 Serum Ferritin 2.3 Magnetic Resonance Imaging 2.4 Image Resolution Index 3 Results and Discussion 4 Conclusion Conflict of Interest References 12 Quantitative Performance Evaluation of Mobile Cone-Beam CT for Head and Neck Imaging Abstract 1 Introduction 2 Materials and Methods 2.1 The Proposed Mobile CBCT 2.2 Radiation Dose 2.3 Image Quality 3 Results 4 Conclusions References 13 Prediction of Alzheimer’s Disease in Mild Cognitive Impairment Using Sulcal Morphology and Cortical Thickness Abstract 1 Introduction 2 Methods 2.1 Data 2.2 Feature Extraction, Selection and Classification 3 Results 4 Discussion Conflict of Interest References 14 Effect of Elimination of Noisy ECG Leads on the Noninvasive Localization of the Focus of Premature Ventricular Complexes Abstract 1 Introduction 2 Materials and Methods 2.1 Body Surface Potential Mapping 2.2 Computed Tomography 2.3 Electrophysiological Study 2.4 Inverse Solution 2.5 Evaluation of the Inverse Solution 3 Results 4 Conclusion Conflict of interest References 15 Effect of Electrode Gel Application Between Patient’s Skin and Electrode Belt on Electrical Impedance Tomography of the Thorax Abstract 1 Introduction 2 Methods 2.1 Minimizing the Factors Influencing EIT Signal 2.2 Set of Pilot Measurements 2.3 Data Analysis 3 Results 4 Discussion 5 Conclusion Conflict of Interest Declaration References 16 Capsaicin Effects on Human Facial and Neck Temperature Abstract 1 Introduction 1.1 Function of Capsaicin in Human Body 2 Methods 2.1 Infrared Thermography in Medicine 2.2 Facial and Neck Temperature Measurement 3 Results 3.1 Infrared Thermography 4 Conclusion Conflict of Interest Declaration References 17 Assessment of Brain Water Content in Peripheral Inflammation by an Optimized Single-Voxel MR Spectroscopy Quantitation Technique Abstract 1 Introduction 2 Methods 2.1 Subjects 2.2 MRI/MRS Acquisition 2.3 Correction Factors in the Calibration of the In Vivo Water Signal Against Aphan 2.4 Spectral Analysis 2.5 Quantification of Brain Tissue Water Content (BWC) 2.6 Statistical Analysis 3 Results 3.1 In Vitro Experiments 3.2 In Vivo Experiments 4 Discussion 5 Conclusions Conflict of Interest References 18 Noninvasive Imaging of the Origin of Premature Ventricular Activity Abstract 1 Introduction 2 Materials and Methods 2.1 ECG Measurement and CT Scanning 2.2 Noninvasive Localization of the PVC Origin 2.3 The EPS and the Ablation Procedure 2.4 Evaluation of the Noninvasive Localization of the PVC Origin 3 Results 4 Discussion and Conclusions Conflict of Interest References 19 Quantitative Assessment of Strabismus and Selected Vision Related Anomalies Abstract 1 Introduction 2 Strabismus Analysis Procedure 2.1 Data Collection 2.2 Image Processing 2.3 Estimation of Deviation 2.4 Graphical User Interface 3 Prediction and Results 4 Conclusion Conflict of Interest References 20 Phase-Contrast Breast-CT: Optimization of Experimental Parameters and Reconstruction Algorithms Abstract 1 Introduction 2 Materials and Methods 2.1 Breast Tissue Sample 2.2 Experimental Setup and Acquisition Parameters 2.3 Data Pre-processing and Reconstruction 2.4 Quantitative Analysis 3 Results and Discussion 4 Conclusions Acknowledgements Compliance with Ethical Requirements References 21 Response of CR Detector Plates for Use in Mammography Equipment Abstract 1 Introduction 2 Methodology 2.1 Mammographic System 2.2 Caracterización de la respuesta de la placa CR y dosimetría 3 Results 4 Conclusions Acknowledgements References 22 Towards In Vivo K-Edge X-Ray Micro-CT with the Pixirad-I/Pixie-III Detector Abstract 1 Introduction 2 Materials and Methods 2.1 Hardware Setup 2.2 Test Object 2.3 Acquisitions 2.4 Image Processing and Reconstruction 3 Results and Discussion 4 Conclusion Conflicts of Interest References Image Processing 23 Diffusion and Perfusion MR Parameters in Locally Advanced Rectal Cancer Management: An Explorative Study Abstract 1 Introduction 2 Methods 2.1 Patients 2.2 Specimens Evaluation 2.3 Imaging 2.3.1 Diffusion weighted MRI 2.3.2 Dynamic Contrast Enhanced MRI 2.4 Feature Extraction 2.4.1 IVIM Parameters 2.4.2 Diffusion kurtosis Parameters 2.4.3 Standard Index of Shape 2.5 Statistical Analysis 2.5.1 Mono-parameter Analysis 2.5.2 Multi-parametric Analysis 3 Results 4 Discussion Conflict of Interest References 24 Mammographic Density Estimation Through Permutation Entropy Abstract 1 Introduction 2 Materials and Methods 2.1 BI-RADS Classification and Breast Density 2.2 Permutation Entropy (PE) for Temporal Series and Images 2.3 Image Database 2.4 Proposed Descriptors 2.5 Density Classifier 3 Results and Discussion 4 Conclusion Conflicts of Interest References 25 Multiregional Radiomics Phenotypes at MR Imaging Predict MGMT Promoter Methylation in Glioblastoma Abstract 1 Introduction 2 Materials and Methods 2.1 Study Cohort 2.2 Image Preprocessing and Tumor Subregions Segmentation 2.3 Multiregional MRI Radiomics Feature Extraction 2.4 Feature Selection and Classification Model 2.5 Statistical Analysis 3 Results and Discussions 4 Conclusions Conflict of Interest References 26 Influence of Image Resolution Property on Aliasing Error of Digital Wiener Spectrum Abstract 1 Introduction 2 Materials and Methods 2.1 Image Simulation 2.2 WS Analysis 2.3 Theoretical WS 3 Results 4 Discussion 5 Conclusion Conflict of interest References 27 Automatic Identification and Extraction of Pectoral Muscle in Digital Mammography Abstract 1 Introduction 2 Methodology 2.1 Dataset 2.2 Developed Algorithm 2.3 Validation 3 Results and Discussion 4 Conclusion Conflict of Interest Statement References 28 Fully Automatic CAD System for Segmentation and Classification of Spinal Metastatic Lesions in CT Data Abstract 1 Introduction 2 Materials and Methods 2.1 Used Dataset 2.2 Data Pre-processing 2.3 Convolutional Neural Network—Architecture and Learning 3 Results and Discussion 4 Conclusion Conflict of Interest References 29 A Classification and Segmentation Combined Two-Stage CNN Model for Automatic Segmentation of Brainstem Abstract 1 Introduction 2 Method 2.1 The Classification-CNN 2.2 The Segmentation-CNN 2.3 The Segmentation-CNN Loss Function 3 Experiments and Results 3.1 Training Details 3.2 Accuracy and Running Time 4 Conclusion Acknowledgements References 30 Biometrics Based on Facial Landmark with Application in Person Identification Abstract 1 Introduction 2 Facial Biometrics Based on Facial Landmarks Extraction 3 Affine Transformation and Image Registration 4 Person Identification 5 Experimental and Result 6 Conclusion References 31 A Computational Tool for Enhancing Ischemic Stroke in Computed Tomography Examinations Abstract 1 Introduction 2 Methods 2.1 Patients and Image Selection 2.2 Developed Approach 2.3 Segmentation Methods 2.4 Observers Evaluation 3 Results 4 Discussion and Conclusion References 32 Improving Priors for USTC via Transmission Tomography: A Simulation Study Abstract 1 Introduction 2 Transmission Algorithms and Filters 3 Method 3.1 Model Generation 3.2 Simulation 3.3 Simultaneous Algebraic Reconstruction Technique and m-MMF 4 Results 5 Discussion and Conclusions Conflict of Interest Declaration References 33 Brain Tumor Classification Using Convolutional Neural Network Abstract 1 Introduction 2 Previous Work 3 Method 3.1 Convolutional Neural Network 3.2 CNN Architecture 3.3 Hyper-parameters Optimization 4 Data 5 Result 6 Conclusion Disclosure References 34 A Novel Method for 3D Reconstruction of Coronary Bifurcation Using Quantitative Coronary Angiography Abstract 1 Introduction 1.1 A Subsection Sample 2 Materials and Methods 2.1 Data Acquisition 2.2 Vessel Segmentation and 2D Centerline Extraction 2.3 Centerline and Lumen Borders 3D Reconstruction 2.4 Registration of the Main and the Side Branch 2.5 Evaluation Methodology 3 Results 4 Discussion 5 Conclusions Conflict of Interest References 35 Machine Learning Techniques for Classification of Breast Cancer Abstract 1 Introduction 2 Methods 3 Results and Discussion 4 Conclusion Declaration of Interest References 36 Segmentation and 3D-Modelling of Single-Rooted Teeth from CBCT Data: An Automatic Strategy Based on Dental Pulp Segmentation and Surface Deformation Abstract 1 Introduction 2 Methods 2.1 Volume Partitioning 2.2 Three-Dimensional Segmentation 3 Results and Discussion 4 Conclusion Conflict of Interest References 37 A Three-Dimensional Quantification of Calcified and Non-calcified Plaque Based on Computed Tomography Coronary Angiography Images: Comparison with Virtual Histology Intravascular Ultrasound Abstract 1 Introduction 2 Materials and Methods 2.1 Preprocessing 2.2 Blooming Effect Removal 2.3 Centerline Extraction 2.4 Estimation of Memberships Functions 2.5 Segmentation of the Lumen, the Outer Wall and CP 2.6 NCP Segmentation 2.7 3D Models Construction 3 CTCA-IVUS Comparison 4 Results 5 Discussion 6 Conclusions Acknowledgements References 38 Creation of Computational Breast Phantoms with Extracted Abnormalities from Real Patient Images Abstract 1 Introduction 2 Materials and Methods 2.1 Clinical Data 2.2 Breast Simulator 2.3 Segmentation Algorithm 2.4 Insertion of Extracted Abnormalities into Computational Breast Phantoms 3 Results and Discussions 3.1 Phantoms 3.2 Segmented Models 3.3 Computational Breast Phantoms with Extracted Abnormalities 4 Conclusions Conflict of Interest References 39 Metal Artifact Reduction by Morphological Image Filtering for Computed Tomography Abstract 1 Introduction 2 Materials and Methods 2.1 Metal Artifact Reduction Approaches 2.2 Morphologically Image Filtering 2.3 Patients 2.4 Evaluation and Statistical Analysis 3 Results 4 Discussion 5 Conclusions Conflict of Interest References 40 Fully Automatic CAD System for Spine Localisation and Vertebra Segmentation in CT Data Abstract 1 Introduction 2 Methodology 3 Results and Discussion 3.1 Our Database 3.2 Publicly Available Datasets 4 Conclusion Conflict of Interest References 41 Hyperdense Middle Cerebral Artery Segmentation in Non Contrast Computed Tomography Abstract 1 Introduction 2 Methodology 2.1 Preprocessing 2.2 Region of Interest 2.3 Feature Extraction 2.4 Segmentation 2.5 Validation 3 Results and Discussion 4 Conclusions References 42 Joint Adaptive Beamforming to Enhance Noise Suppression for Medical Ultrasound Imaging Abstract 1 Introduction 2 Beamformers 3 Proposed Method 4 Results and Discussion 5 Conclusion References 43 Label-Free Nuclear Staining Reconstruction in Quantitative Phase Images Using Deep Learning Abstract 1 Introduction 2 Materials and Methods 2.1 Experimental Data 2.2 Used Models 2.3 Preprocessing 2.4 Network Implementation 2.5 Nucleus Segmentation 3 Results 4 Discussion 5 Conclusions Conflict of Interest References 44 Performance Comparison of Segmentation Algorithms for Image Quality Degraded MR Images Abstract 1 Introduction 2 Methodology 2.1 JPEG Compression Algorithm 2.2 Intracranial Area, White Matter and Gray Matter Segmentation 3 Results 4 Conclusion Conflict of Interest References 45 Application of Low-Cost 3D Printing for Production of CT-Based Individual Surgery Supplies Abstract 1 Introduction 2 Introduction 2.1 Research Problem 2.2 Methodology of Design and Rapid Manufacturing of Medical Products 2.3 The Fused Deposition Modelling Technology 2.4 Mandibular Reconstruction Template—Case Description 2.5 Course of Studies 3 Results 4 Discussion 5 Conclusions Conflict of Interest References 46 Examination of the Spatial Structure of Pigs’ Melanoma in Tissue Sections Based on Histology and Mass Spectrometry Abstract 1 Introduction 2 Methods 2.1 Data Collection 2.2 Data Integration 2.3 Clustering 2.4 Statistical Analysis 3 Results 3.1 Data Integration 3.2 Clustering 4 Conclusion Acknowledgements References 47 Automatic Characterization of Plaques and Tissue in IVOCT Images Using a Multi-step Convolutional Neural Network Framework Abstract 1 Introduction 2 Methods 2.1 Materials 2.2 Patches Analysis 2.3 Classification of Plaques—Transfer Learning 2.4 Multi-step Processing 3 Results 4 Discussion 5 Conclusion Conflict of interest References 48 Iterative Methods for Fast Reconstruction of Undersampled Dynamic Contrast-Enhanced MRI Data Abstract 1 Introduction 2 Models 2.1 TV Regularization with Pre-estimated Temporal Basis 2.2 Low-Rank Plus Sparse (L + S) 2.3 ICTGV Model 3 Data Acquisition and Evaluation Methods 4 Results and Discussion 5 Conclusions Conflict of Interest References 49 Multimodality Image Fusion of the Liver Using Structure-Guided Deformable Image Registration in Velocity AI—What Is the Preferred Approach? Abstract 1 Introduction 2 Materials and Methods 2.1 Structure Segmentation 2.2 Deformable Image Registration 3 Results 4 Discussion 5 Conclusion Conflict of Interest References 50 First Validation of Semi-automatic Liver Segmentation Algorithm Abstract 1 Introduction 2 Methods 3 Results 4 Discussion 5 Conclusion Conflict of Interest References 51 Image Quality Optimization and Soft Tissue Visualization in Cone-Beam CT Imaging Abstract 1 Introduction 2 Materials and Methods 2.1 Attenuation Physics 2.2 Experiments 3 Results 3.1 Water Phantom 3.2 Wedge Phantom 4 Discussion and Conclusions Conflicts of Interest References 52 A Method to Detect Potentially Malignant Skin Lesions Through Image Segmentation Abstract 1 Introduction 2 Materials and Methods 2.1 Region of Interest 2.2 Asymmetry Criterion from ABCDE Rule for Melanoma Detection 2.3 Border Criterion from ABCDE Rule for Melanoma Detection 2.4 Colour Variation Criterion from ABCDE Rule for Melanoma Detection 2.5 Texture Parameter for Melanoma Diagnosis 3 Results 4 Discussion and Conclusion Conflict of Interest References Information Technology in Healthcare 53 A Gait Character Analyzing System for Osteoarthritis Pre-diagnosis Using RGB-D Camera and Supervised Classifier Abstract 1 Introduction 2 Materials and Methods 2.1 Gait Data Acquisition and Analysis 2.2 Gait Features and Classifier 3 Results 3.1 Experimental Set up 3.2 Calculating Parameters 3.3 Classification for OA Patients 4 Discussion and Conclusion Conflict of Interest References 54 Architecture and Organization of a Computational System for the Management of Data from Individuals with Parkinson’s Disease Abstract 1 Introduction 2 Materials and Methods 2.1 Model-View-Controller Architecture and Development Environment 3 Results 4 Discussion and Conclusion Conflicts of Interest References 55 Developing an Automated Clinical Trending Tool for the Neonatal Intensive Care Unit (NICU) Abstract 1 Introduction 2 Methodology 2.1 Displaying the Heart Rate Data 2.2 Using a Filter 2.3 Displaying the Oxygen Saturation Data 2.4 Visualization Tools 3 Results and Discussions 4 Conclusions Acknowledgements References 56 Data Analytics for Metabolic Syndrome Diagnostics Abstract 1 Introduction 2 CRISP-DM 2.1 Business Understanding 2.2 Data Understanding 2.3 Data Preparation 2.4 Modelling 2.5 Evaluation 3 Conclusion Conflicts of Interest References 57 Medical Expert System with the Properties of Artificial Intelligence Abstract 1 Introduction 2 Integrality and Meta Logic 3 Tolerance and Harmonization 4 Conclusions References 58 A Simple Room Localization Method to Find Technology in a Big Trauma Center Abstract 1 Introduction 1.1 Methods for Position Calculation 1.2 Methods for Reducing the Variability of Signals 2 Methods 2.1 Selected Methods for Study 3 Results and Discussion 4 Conclusions Conflict of Interest References 59 The Influence of the Voice Acquisition Method to the Mental Health State Estimation Based on Vocal Analysis Abstract 1 Introduction 2 Materials and Methods 2.1 Vocal Analysis 2.2 Beck’s Depression Inventory 2.3 Experiment 2.4 Analysis of Data 3 Results 3.1 Effect of the Recording Method 4 Discussion 5 Conclusion Conflict of Interest References 60 Using Artificial Neural Network to Predict Functional Recovery of Patients Treated by Intravenous Thrombolysis in Acute Ischemic Stroke Abstract 1 Introduction 2 Materials and Methods 2.1 Data Collection 2.2 ANN Model Construction and Evaluation 3 Results 4 Conclusions and Discussion References 61 Estimation of the Heart Rate Variability Features via Recurrent Neural Networks Abstract 1 Introduction 1.1 Related Work 2 Methods 2.1 Dataset Description 2.2 ECG Preprocessing 2.3 LSTM Architecture for the ECG Analysis 2.4 Training and Evaluation 3 Results 4 Discussion Conflict of Interest References 62 Study on Non-contact Heart Beat Measurement Method by Using Depth Sensor Abstract 1 Introduction 2 Method 2.1 System Configuration 2.2 Detection of Heart Beat 3 Experiment and Result 4 Conclusion Acknowledgements References 63 Design Reflection on Mobile Electronic Data Capturing Forms in African Rural Settings Abstract 1 Introduction 2 Method 3 Results 4 Discussion 5 Conclusion Conflict of Interest References 64 Evaluation Methodology and Measurement of Physiological Data to Determine Operational Preparedness of Air Defense Staff: Preliminary Results Abstract 1 Introduction 2 Methods 2.1 Participants 2.2 Measurement Equipment 2.3 Test Procedure 2.4 Data Processing 3 Results 4 Discussion 5 Conclusion Conflict of Interest References 65 A Multiple Criteria Decision Making System for Setting Priorities Abstract 1 Introduction 2 Materials and Methods 3 Results 3.1 AOGrupo 3.2 An Application of AOGrupo in a Real Scenario 4 Discussion Conflicts of Interest References 66 Towards Computer Supported Search for Semiological Features in Epilepsy Seizure Classification Abstract 1 Introduction 2 ASTEP: Annotation and Statistical Tool for EPilepsy 3 User Experience and Preliminary Results 4 Conclusions Acknowledgements References 67 Scoring System for the One-Year Mortality Prediction of Sepsis Patients in Intensive Care Units Abstract 1 Introduction 2 Methods 2.1 Data Description 2.2 Score Development 3 Results 4 Conclusions Conflicts of Interest References 68 Computerized Cognitive Assessment System for Dementia Screening Application Abstract 1 Introduction 1.1 Background 1.2 Cognitive Assessments 1.3 Computerization 1.4 Serious Game 2 Materials and Methods 2.1 Computerized Cognitive Assessment System 2.2 Subject Information 2.3 Experimental Design 2.4 Questionnaire 3 Results and Discussion 3.1 Results 3.2 Discussion 4 Conclusion References 69 Modeling Biological Data Through Dynamic Bayesian Networks for Oral Squamous Cell Carcinoma Classification Abstract 1 Introduction 2 Materials and Methods 2.1 Transcriptomic Dataset 2.2 Differentially Expressed Genes 2.3 Transcription Factors 2.4 Dynamic Bayesian Network Modeling 3 Results and Discussion 3.1 Differentially Expressed Genes 3.2 Transcription Factors 3.3 Modeling OSCC Through DBNs 4 Conclusions Conflicts of Interest References 70 A Process Modelling and Analytic Hierarchy Process Approach to Investigate the Potential of the IoT in Health Services Abstract 1 Introduction 2 Method 2.1 Process Modeling 2.2 Analytical Hierarchy Process 3 Results 4 Conclusions Conflicts of Interest References 71 A Virtual CPR (Cardio-Pulmonary Resuscitation) Learning System Using Motion Capture Device Abstract 1 CPR Training for Non-medical Persons 2 Hand Motion Capture Device for Simulator 3 CPR Training Scenarios 3.1 Reference AED Trainer 3.2 CPR Scenarios 4 Implementation of Virtual CPR Learning System 4.1 System Development Environment 4.2 Simulated Procedure of AED Usage 4.3 Tutorials 4.4 Simulated Procedure of Chest Compression 5 Usability Evaluation 6 Discussion Conflicts of Interest References 72 Usability of Electronic Patient Records for Assessment and Care Planning in Nursing Homes Abstract 1 Background 2 Research Objectives 3 Study Design and Methods of Data Collection and Analysis 3.1 Study Design 3.2 Data Collection 3.3 Sampling and Inclusion Criteria 3.4 Data Analysis 4 Ethical Issues 4.1 Assessment and Management of Risk 4.2 Consent 5 Impact of Results Conflicts of Interest References 73 Data Security and Raw Data Access of Contemporary Mobile Sensor Devices Abstract 1 Introduction 2 Materials 3 Methods 3.1 Data Access 3.2 Data Interpretation 3.3 Results 4 Conclusion 5 Outlook Conflict of Interest References 74 Security Mechanism for Medical Record Exchange Using Hippocratic Protocol Abstract 1 Introduction 2 Test Model Elements 2.1 Hardware 2.2 Server Software 2.3 Terminal Software 3 Test Performed 3.1 Hippocratic Characteristics 3.2 Time Response 3.3 Persistence of Data in the Terminal 4 Discussion 5 Conclusion Conflict of Interest References 75 An Engineering Module to Identify Potential Diabetes Patients and Preventive Measures for Diabetes in Developing Countries like Bangladesh Abstract 1 Background 2 Current Status of Diabetes in Southeast Asia 3 Diabetes Related Software Apps Survey 3.1 POWER2DM 3.2 MISSION-T2D 3.3 ProEmpower 4 Objectives 5 Methods and Related Works 6 Expected Outcomes 7 Conclusion Conflict of interest References 76 MULTISAB: A Web Platform for Analysis of Multivariate Heterogeneous Biomedical Time-Series Abstract 1 Introduction 2 The Processing Subproject Architecture 2.1 Implemented Frameworks 3 Analysis Scenario 4 Conclusion Conflict of interest References 77 Technologies Catalog to Support the Identification of User Behavior During Usability Tests Abstract 1 Introduction 2 Method 3 Study of Behavioral Categories 4 Technologies That Detect User Behavior 5 Conclusion References 78 t-SNE Applied to Discriminate Healthy Individuals from Those with Parkinson’s Disease Executing Motor Tasks Detected by Non-contact Capacitive Sensors Abstract 1 Introduction 2 Methods 2.1 Experimental Setup 2.2 Signal Preprocessing 2.3 Feature Extraction 2.4 Data Visualization 3 Results 3.1 Typical Waveforms 3.2 Feature Analysis 3.3 Data Visualization 4 Discussion and Conclusion Acknowledgements Conflicts of Interest References 79 Electronic Delivery Book: Structured Database Enables Analysis of Perinatal Risk Factors Abstract 1 Introduction 2 Electronic Delivery Book 3 Critical Factor Analysis 3.1 Data and Features 3.2 Statistic Evaluation 3.3 Results 4 Conclusion Acknowledgements Conflict of Interest References 80 Wearable Cardiorespiratory Monitoring System for Unobtrusive Free-Living Energy Expenditure Tracking Abstract 1 Introduction 2 System Architecture 3 Experiment 4 Results and Discussion 5 Conclusion Acknowledgements and Conflict of Interest References 81 Design Variations for Improved Usability of Mobile Data Capture in Rural Uganda Abstract 1 Introduction 2 Methods 3 Results 3.1 Individual Expert Review 3.2 Mid-Fidelity Prototypes 3.3 User Preference Testing 4 Discussion 5 Conclusion Conflict of Interest References 82 Advancing Medical Practice Through Computer Expert Systems Abstract 1 Introduction 2 Literature Review 2.1 Components of Expert Systems 2.2 Applications of Expert Systems 2.3 Medical Practice, Malaria, Developing Countries and Expert Systems 3 Methodology 4 Results and Discussion 5 Conclusion Conflict of Interest References 83 Propose a Model of Multimedia Electronic Patient Record System for Sri Lankan Public Health Sector Abstract 1 Introduction 2 Materials and Methods 3 Results and Discussion 4 Conclusion References 84 Multiple Sclerosis Application Design with Medical Expert Evaluation Abstract 1 Introduction 2 Method 3 Results 3.1 First Design Iteration 3.2 Second Design Iteration 4 Discussion 5 Conclusions Compliance with Ethical Standards References 85 Design Features for Usable Mobile Electronic Data Capturing Forms: The Form Developers’ Perspective Abstract 1 Introduction 2 Methods 3 Results 4 Discussion 5 Conclusion and Recommendation Ethics References 86 Task-Based Approach Recommendations to Enhance Data Visualization in the Kenya National Health Data Warehouse Abstract 1 Introduction 2 Methods 3 Results 3.1 Tasks: Distribution of EMRs and Patient Health Outcomes