Visual Prosthesis : A Concise Guide

For the millions of people with untreatable blindness the thought of a visual prosthesis that would allow them to live a normal life has always been a distant hope. There have been intermittent bright spots that periodically fan that hope such as when Dr. Dobelle’s visual prosthesis patient drove a car in an empty parking lot. This book will serve as an update of the work in developing a visual prosthesis. Chapters discuss the physiologic and engineering issues, alternative strategies, and patents, as well as recent research studies. Visual Prosthesis - A Concise Guide is a must-have resource for ophthalmologists, neurologists, engineers and physicists. Preface Contents Chapter 1: Blindness Definitions Prevalence Impact of Vision Impairment Personal Impact Causes Chapter 2: Anatomy of the Visual System Chapter 3: History Chapter 4: Questions Surface or Intracortical Electrodes Phosphene Mapping Machine Learning Electrode Placement Stimulation Parameters: Phosphene Threshold Optogenetics Magnetic Stimulation Chapter 5: Cortical Visual Prosthesis Studies Early Feasibility Study of the Orion Visual Cortical Prosthesis System Sponsor Brief Summary Detailed Description Arms and Interventions Primary Outcome Measures Secondary Outcome Measures Criteria Locations Sponsors and Collaborators Investigators Publications Feasibility of Stimulating the Visual Cortex in Blind Sponsor Arms and Interventions Primary Outcome Measures Criteria Locations Sponsors and Collaborators Investigators A Phase I Feasibility Study of an Intracortical Visual Prosthesis (ICVP) for People with Blindness (ICVP) Sponsor Collaborators Brief Summary Detailed Description Primary Outcome Measures Secondary Outcome Measures Criteria Contacts Locations Sponsors and Collaborators Investigators Publications Keywords Provided by Illinois Institute of Technology Development of a Cortical Visual Neuroprosthesis for the Blind (CORTIVIS) Sponsor Collaborator Information Provided by (Responsible Party) Brief Summary Detailed Description Primary Outcome Measures Secondary Outcome Measures Criteria Contacts Locations Sponsors and Collaborators Investigators Publications Additional Relevant Terms Software Developed Inside the CORTIVIS Consortium A Study to Evaluate the BrainPort Vision Device in Individuals Blinded by Traumatic Injury Sponsor Collaborators Brief Summary Primary Outcome Measures Other Outcome Measures Criteria Locations Sponsors and Collaborators Investigators Publications Automatically Indexed to This Study by ClinicalTrials.gov Identifier (NCT Number) Keywords Provided by Wicab Additional Relevant Terms BrainPort Vision Pro Study Chapter 6: Retinal Implant Studies Compensation for Blindness with the Intelligent Retinal Implant System (IRIS V2) in Patients with Retinal Dystrophy (IRIS 2) Sponsor Information Provided by (Responsible Party) Brief Summary Arms and Interventions Primary Outcome Measures Secondary Outcome Measures Eligibility Criteria Criteria Locations Sponsors and Collaborators Keywords Provided by Pixium Vision SA Additional Relevant MeSH Terms Safety and Efficacy of Subretinal Implants for Partial Restoration of Vision in Blind Patients Sponsor Information Provided by (Responsible Party) Study Description Brief Summary Study Design Arms and Interventions Outcome Measures Primary Outcome Measures Secondary Outcome Measures Eligibility Criteria Criteria Contacts and Locations Locations Sponsors and Collaborators Investigators Publications of Results Keywords Provided by Retina Implant AG Additional Relevant MeSH Terms Retina Implant Pilot Trial to Evaluate Safety and Efficacy in Blind Patients Having Degenerated Photoreceptors Sponsor Information Provided by Retina Implant AG Brief Summary Detailed Description Study Design Arms and Interventions Outcome Measures Primary Outcome Measures Secondary Outcome Measures Eligibility Criteria Criteria Contacts and Locations Locations Sponsors and Collaborators Investigators Publications Automatically Indexed to This Study by ClinicalTrials.gov Identifier (NCT Number) Keywords Provided by Retina Implant AG Additional Relevant MeSH Terms Safety and Efficacy of Subretinal Implants for Partial Restoration of Vision in Blind Patients Sponsor Information Provided by (Responsible Party) Brief Summary Arms and Interventions Outcome Measures Primary Outcome Measures Secondary Outcome Measures Eligibility Criteria Criteria Contacts and Locations Locations Sponsors and Collaborators Investigators Publications of Results Other Publications Publications Automatically Indexed to This Study by ClinicalTrials.gov Identifier (NCT Number) Keywords Provided by Retina Implant AG Additional Relevant MeSH Terms Feasibility Study of Compensation for Blindness with the PRIMA System in Patients with Dry Age-Related Macular Degeneration (PRIMA FS) Sponsor Information Provided by (Responsible Party) Brief Summary Detailed Description Study Design Arms and Interventions Outcome Measures Primary Outcome Measures Secondary Outcome Measures Eligibility Criteria Criteria Contacts and Locations Locations Sponsors and Collaborators Publications Automatically Indexed to This Study by ClinicalTrials.gov Identifier (NCT Number) Keywords Provided by Pixium Vision SA Additional Relevant MeSH Terms PRIMA US-Feasibility Study in Atrophic Dry AMD (PRIMA-FS-US) Sponsor Collaborator Information Provided by (Responsible Party) Study Description Brief Summary Detailed Description Study Design Arms and Interventions Outcome Measures Primary Outcome Measures Secondary Outcome Measures Eligibility Criteria Criteria Contacts and Locations Contacts Locations Sponsors and Collaborators Investigators Keywords Provided by Pixium Vision SA Additional Relevant MeSH Terms Chapter 7: Other Projects Artificial Vision for the Blind vOICe Auditory Display Other Approaches Chapter 8: US Visual Prosthesis Patents Chapter 9: Noninvasive Brain Treatment Modalities Light PBM for Acute Stroke Traumatic Brain Injury (TBI) Dementia Transcranial Magnetic Stimulation (TMS) Transcranial Direct Current Stimulation (tDCS) Transcranial Doppler Sonography (TCD) Hyperbaric Oxygen Neurofeedback Virtual Reality External Stimulation An Alternative to Fixed Electrodes? Bibliography Index