Virology and Immunology in Multiple Sclerosis: Rationale for Therapy : Proceedings of the International Congress, Milan, December 9–11, 1986

**Contents:** Immunology, Virology, and Immunogenetics of Multiple Sclerosis.- Risk Factors, Course, Prognosis, and Treatment of Multiple Sclerosis.- Short Communications.- Subject Index. Front Matter....Pages I-VIII Front Matter....Pages 1-1 Immunocyte Abnormalities in Multiple Sclerosis....Pages 3-7 Different T-Cell Response to Myelin Basic Protein in Multiple Sclerosis Patients and in Healthy Subjects....Pages 8-12 Glial Cells and Products of Activated Inflammatory Cells: Implications for Pathogenesis and Treatment of Multiple Sclerosis....Pages 13-20 Intrathecal IgG Synthesis in Multiple Sclerosis: Correlation with Clinical Parameters....Pages 21-31 Loss of Reliability and Sensitivity of Agarose Isoelectric Focusing and Quantitative Formulae in the Detection of Intrathecally Synthesized IgG in the Presence of Blood-Brain Barrier Damage....Pages 32-34 Lymphocyte Subpopulations as Markers of Disease Activity in Multiple Sclerosis*....Pages 35-42 Serological Studies of Patients with Multiple Sclerosis, controls, and Patients with Other Neurological Diseases: Antibodies to HTLV-I, HTLV-II, HIV, and STLV-III....Pages 43-50 Correlation of Oligoclonal IgG Bands and Viral Antibodies in Twins with Multiple Sclerosis....Pages 51-54 Detection of HLA Class II Restriction Fragment Length Polymorphisms in Multiple Sclerosis Using Pooled DNA Samples....Pages 55-63 HLA Studies in the Multiple Sclerosis Population....Pages 65-69 Multiple Sclerosis: Phenotypic Immunogenetic Markers and Nucleic Acid Biochemistry....Pages 70-77 Genetics in Multiple Sclerosis — with Special Emphasis on Twin Studies....Pages 78-83 Front Matter....Pages 85-85 Risk Factors, Course, and Prognosis of Multiple Selerosis....Pages 87-109 Epidemiological Studies of Multiple Sclerosis in Western Norway: Possible Factors in Etiology and Prognosis....Pages 110-114 Multiple Sclerosis: Stochastic Models of Prognosis....Pages 115-124 Studies of the Natural History of Multiple Sclerosis....Pages 125-132 Space-Time Aggregation in a Small Village in Italy: Buti (Pisa)....Pages 133-140 Immunotherapy in Multiple Sclerosis: Arguments for Early Treatment....Pages 141-146 Selective Immunosuppression in Multiple Sclerosis....Pages 147-152 Use of Azathioprine in Multiple Sclerosis....Pages 153-161 Front Matter....Pages 85-85 Immunosuppression with Azathioprine in Multiple Sclerosis....Pages 162-171 Multiple Sclerosis: Preliminary Reports of a Therapeutical Trial and Magnetic Resonance Imaging Correlates....Pages 172-178 New Trends for Treatment in Multiple Sclerosis....Pages 179-185 Front Matter....Pages 187-187 Limitations of Peroxidase Staining in the Detection of CSF IgA Separated by Agarose Isoelectric Focusing....Pages 189-192 Failure to Detect Anti-HTLV-III Antibodies in Serum and CSF of 84 Neurological Patients....Pages 193-195 Absence of Serum HTLV-I and -III Antibodies in Multiple Sclerosis Patients....Pages 196-197 Antigen Histocompatibility (HLA) in Multiple Sclerosis Patients from Gorski Kotar, Yugoslavia....Pages 198-200 Diagnostic and Predictive Value of Nonclinical Tests in Retrobulbar Optic Neuritis....Pages 201-204 Contribution of Magnetic Resonance Imaging in the Assessment of Multiple Sclerosis....Pages 205-207 Serial Evoked Potentials and Disease Progression in Multiple Sclerosis....Pages 208-213 Clinical and Immunological Findings After Treatment with Thymostimulin in Multiple Sclerosis....Pages 214-217 Treatment of Multiple Sclerosis with a Mega Dose of 6-Methylprednisolone....Pages 218-220 Long-Term Hyperbaric Oxygen in Chronic Progressive Multiple Sclerosis: A Placebo-Controlled Double-Blind Randomized Study with Evoked Potential Evaluation....Pages 221-224 Psychotherapy in Patients with Multiple Sclerosis....Pages 225-227 Cognitive Impairment in Multiple Sclerosis....Pages 228-230 Back Matter....Pages 231-232