Veterinary pharmacology and toxicology. Proceedings from the 2nd European Association for Veterinary Pharmacology and Toxicology held at Toulouse, 13th-17th September, 1982

Front Matter....Pages i-xxii Front Matter....Pages 1-1 Perinatal pharmacology in ruminant models....Pages 3-22 Placental transfer of drugs in ruminant animals....Pages 23-37 Drug disposition in the fetus....Pages 39-48 Drug disposition in the newborn....Pages 49-55 Postnatal development of renal function in goats....Pages 57-62 Developmental patterns of penicillin G excretion....Pages 63-72 Drug effects during development and carcinogenicity....Pages 73-81 APPENDIX....Pages 82-92 Chemical induced teratogenesis....Pages 93-97 Levamisole as an immunomodulator in the prevention of neonatal disease....Pages 99-103 Development and prophylaxis of anaemia in calves and lambs....Pages 105-113 Oral fluid therapy: some concepts on osmolality, electrolytes and energy....Pages 115-130 Front Matter....Pages 131-131 Drug bioavailability in the developing ruminant....Pages 133-140 Oral antibacterial therapy in pre- and postweaning calves....Pages 141-149 Influence of ruminant gastrointestinal physiology on the pharmacokinetics of drugs in dosage forms administered orally....Pages 151-163 Ruminal influences on drug action....Pages 165-181 Recent developments in the treatment of metabolic diseases....Pages 183-191 Drug excretion by the mammary gland....Pages 193-202 Pharmacology of uterine motility and relaxation....Pages 203-211 New prostaglandins: present studies and future....Pages 213-220 Front Matter....Pages 131-131 Worm diseases: economic aspects of anthelmintic treatment....Pages 221-224 Pharmacological basis of the treatment of helminth in cattle....Pages 225-233 Pharmacokinetics of albendazole, fenbendazole and oxfendazole....Pages 235-240 Pharmacokinetics of levamisole in goats and pigs....Pages 241-244 Appendix....Pages 245-245 The prophylactic activity of imidocarb against tick-transmitted parasitic infections....Pages 247-254 Front Matter....Pages 255-255 The distribution and function of histamine receptors....Pages 257-262 Serotonin and S 2 antagonists in veterinary medicine....Pages 263-281 Dopaminergic control of gastrointestinal motility....Pages 283-298 Vomiting and antiemetics in small animal practice....Pages 299-305 Diarrhoea and antidiarrhoeal drugs....Pages 307-320 Pharmacology and comparative toxicology of non-steroidal anti-inflammatory agents....Pages 321-331 Clinical pharmacokinetic studies of digoxin and digitoxin in the dog....Pages 333-339 Influence of anaesthetics and ancillary agents on cardiovascular and respiratory systems in the horse....Pages 341-351 Steroidal anti-inflammatory agents in the horse: pharmacokinetics and action on the adrenal gland....Pages 353-366 Spasmolytic analgesic drugs and small intestinal function in the horse....Pages 367-370 Physiological, pharmacological and therapeutic aspects of some gastrointestinal disorders in the horse....Pages 371-380 Pharmacological control of reproductive mechanisms in the equine female....Pages 381-394 Front Matter....Pages 395-395 Clinical utility and limitations of pharmacokinetics....Pages 397-414 Pharmacological approach of drugs used in coronary insufficiency and cerebrovascular pathology....Pages 415-418 Front Matter....Pages 395-395 Appendix....Pages 419-419 Fever, trace metals and disease. The effect of antipyretic agents....Pages 421-427 Efficacy of penicillin against Streptococcus zooepidemicus . Infection model in the horse....Pages 429-435 Receptor binding methods: application to the study of cyclopyrrolones, a new family of minor tranquillizers....Pages 437-449 Multiplicity of kappa opiate sites in the central nervous system....Pages 451-463 Hepatocyte cultures as a research tool in pharmacology and toxicology....Pages 465-478 Metabolic radical formation from halothane and enflurane and its modification by enzyme induction and inhibition....Pages 479-484 Anaesthesia in pharmacological research....Pages 485-500 Evaluation of analgesic drug combinations....Pages 501-522 Enzyme induction and inhibition....Pages 523-537 Rapid induction of cirrhosis in the liver. A model of hepatic disease....Pages 539-552 Behavioural analysis of drug action....Pages 553-563 Experimental models for respiratory diseases of ruminants and of swine....Pages 565-592 Front Matter....Pages 593-593 Environmental pollution: the animal as source, indicator and transmitter....Pages 595-608 Residues of drugs and pesticides in milk....Pages 609-623 Mycotoxin residue problem and human health hazard....Pages 625-640 Residues of xenobiotics in animals, milk, and environment in the light of a 13 year surveillance....Pages 641-645 Persistence in milk of active antimicrobial intramammary substances....Pages 647-657 Evaluation of drug residues in animal tissues....Pages 659-670 Photosensitization in ruminants: porphyrins and phylloerythrin....Pages 671-680 Front Matter....Pages 593-593 Fluorosis in the sheep: new data....Pages 681-690 Chloramphenicol-propylene glycol toxicity following constant intravenous infusion in horses....Pages 691-696 Heavy metal intoxications in horses....Pages 697-714 Evaluation of subclinical lead poisoning in dairy cattle....Pages 715-724 Poisoning of animals in the Los Angeles area with pesticides (1981)....Pages 725-731 Toxicological field data in ruminants....Pages 733-736 Adverse drug reactions and interactions (1979–1981)....Pages 737-744 Front Matter....Pages 745-748 Medicated feed in French Legislation and European Economic Community....Pages 749-751 Medicated feed: problems and solutions....Pages 752-757 Medicated feed manufacturing....Pages 758-759 Animal drugs and the evaluation of residues in milk and meat....Pages 760-763 Drugs for prevention or treatment of internal parasites in farm animals. Particular cases of medicated feed....Pages 764-767 Virginiamycin activity and safety in ruminants....Pages 768-770 The use of monensin in cattle: effectiveness and safety to the consumer....Pages 771-773 Effect of lasalocid sodium on digestion in sheep....Pages 774-778 Evaluation of the efficacy of lasalocid sodium on the fattening of steers....Pages 779-781 Salinomycin, a new polyether antibiotic for fattening cattle and lambs....Pages 782-785 Salinomycin activity in ruminants....Pages 786-794 Front Matter....Pages 795-797 Detomidine hydrochloride. A novel imidazole-type sedative analgesic....Pages 798-799 The cardiovascular effects of ketamine, thiopentone and methohexitone after xylazine premedication in horses....Pages 800-802 Front Matter....Pages 795-797 Study on interactions between chloramphenicol and intravenous anaesthetics....Pages 803-803 The neuromuscular blocking action of a new muscle relaxant atracurium in the dog....Pages 804-805 Haemodynamic effects of methoxyflurane in dogs....Pages 806-807 Afferent inputs to mammalian spinal neurons: studies with anaesthetic and analgesic agents....Pages 808-810 Evaluation of etomidate and fentanyl in dog anaesthesia....Pages 811-812 Interactions between dissociative anaesthetics and neurotransmitter receptors in the mammalian central nervous system....Pages 813-816 Clinical pharmacology of ketamine in the pig....Pages 817-819 The use of a combination of xylazine and ketamine in calves....Pages 820-822 E.e.g. frequency analysis of barbiturate and ketamine anaesthesia....Pages 823-824 Back Matter....Pages 825-838