Users' Guides to the Medical Literature: Essentials of Evidence-Based Clinical Practice, Third Edition (Uses Guides to Medical Literature)

## The streamlined companion to the classic __Users' Guides to the Medical Literature__--fully updated and revised This compact guide condenses the most clinically relevant content of the landmark __Users' Guides to the Medical Literature__ to help you incorporate evidence-based medicine into your practice. You will learn the principles of evidence-based medicine, how your practice can benefit from the constant stream of new medical literature, and how to differentiate good medical evidence from that which is inadequate or misleading. This edition includes numerous updates, several new chapters, and a greater emphasis on the role of patient preferences and preappraised resources. Cover 1 Title Page 4 Copyright Page 5 Contents 8 Contributors 12 Foreword 18 Preface 24 The Foundations 30 1 How to Use the Medical Literature—and This Book—to Improve Your Patient Care 30 2 What Is Evidence-Based Medicine? 38 3 What Is the Question? 54 4 Finding Current Best Evidence 72 5 Why Study Results Mislead: Bias and Random Error 114 Therapy 124 6 Therapy (Randomized Trials) 124 7 How to Use a Noninferiority Trial 156 8 Does Treatment Lower Risk? Understanding the Results 178 9 Confidence Intervals: Was the Single Study or Meta-analysis Large Enough? 194 Harm (Observational Studies) 208 10 Harm (Observational Studies) 208 Diagnosis 240 11 The Process of Diagnosis 240 12 Diagnostic Tests 252 Prognosis 280 13 Prognosis 280 Summarizing the Evidence 298 14 The Process of a Systematic Review and Meta-analysis 298 15 Understanding and Applying the Results of a Systematic Review and Meta-analysis 320 16 Network Meta-analysis 356 Moving From Evidence to Action 386 17 How to Use a Patient Management Recommendation: Clinical Practice Guidelines and Decision Analyses 386 18 Decision Making and the Patient 418 Glossary 446 A 446 B 449 C 456 D 466 E 469 F 474 G 476 H 477 I 479 J 484 K 484 L 485 M 487 N 490 O 492 P 494 Q 501 R 502 S 507 T 514 U 517 V 518 W 519 Index 522 A 522 B 522 C 523 D 526 E 527 F 529 G 530 H 530 I 531 J 531 K 531 L 532 M 532 N 533 O 534 P 535 Q 537 R 538 S 540 T 543 U 544 V 545 W 545 Y 545 Content: Machine generated contents note: The Foundations -- 1. How to Use the Medical Literature -- and This Book -- to Improve Your Patient Care -- 2. What Is Evidence-Based Medicine? -- 3. What Is the Question? -- 4. Finding Current Best Evidence -- 5. Why Study Results Mislead: Bias and Random Error -- Therapy -- 6. Therapy (Randomized Trials) -- 7. How to Use a Noninferiority Trial -- 8. Does Treatment Lower Risk? Understanding the Results -- 9. Confidence Intervals: Was the Single Study or Meta-analysis Large Enough? -- Harm (Observational Studies) -- 10. Harm (Observational Studies) -- Diagnosis -- 11. The Process of Diagnosis -- 12. Diagnostic Tests -- Prognosis -- 13. Prognosis -- Summarizing the Evidence -- 14. The Process of a Systematic Review and Meta-analysis -- 15. Understanding and Applying the Results of a Systematic Review and Meta-analysis -- 16. Network Meta-analysis -- Moving From Evidence to Action -- 17. How to Use a Patient Management Recommendation: Clinical Practice Guidelines and Decision Analyses -- 18. Decision Making and the Patient. The Only Corel-Authorized Guide to CorelDRAW X7 CorelDRAW X7: The Official Guide shows you how to create photorealistic illustrations, lay out text and graphics, import and edit photos, add special effects to vector art and photos, and transform 2D objects into 3D artwork. You'll also get expert tips for printing work that matches what you've designed on your monitor. Step-by-step tutorials based on downloadable sample files let you learn by doing. Explore and master CorelDRAW's menus, palettes, and dockers Add Paragraph Text, Artistic Text, and custom-shaped text to your designs Explore the new Content Exchange for access to new, exciting patterns and other fills Create the illusion of 3D objects with the Perspective and Extrude tools Dramatically edit objects with the Smear, Twirl, Attract, Repel, and Distortion tools Add elements of photorealism to your drawings with lens effects, transparency, shadows, glows, and bevels Combine photos with vector graphics in CorelDRAW, and perform advanced editing in PHOTO-PAINT Designed to help you to put key evidence-based medicine protocols into daily clinical practice. This detailed, yet highly readable reference demystifies the statistical, analytical, and clinical principles of evidence-based medicine, giving you a hands-on, practical resource. Here, you'll learn how to distinguish solid medical evidence from poor medical evidence, devise the best search strategies for each clinical question, critically appraise the medical literature, and optimally tailor evidence-based medicine for each patient. Current, authoritative content covering how to: avoid being misled by biased presentations of research findings; interpret the significance of clinical trials that are discontinued early; influence clinician behavior to improve patient care; and apply key strategies for teaching evidence-based medicine The streamlined companion to the classic Users' Guides to the Medical Literature--fully updated and revised This compact guide condenses the most clinically relevant content of the landmark Users' Guides to the Medical Literature to help you incorporate evidence-based medicine into your practice. You will learn the principles of evidence-based medicine, how your practice can benefit from the constant stream of new medical literature, and how to differentiate good medical evidence from bad. This edition includes several new chapters and a new emphasis on the role of patient preferences and preappraised resources. A comprehensive online resource for teaching, learning, and applying evidence-based medicine to improve patient care. The streamlined companion to the classic Users' Guides to the Medical Literature --fully updated and revised This compact guide condenses the most clinically relevant content of the landmark Users' Guides to the Medical Literature to help you incorporate evidence-based medicine into your practice. You will learn the principles of evidence-based medicine, how your practice can benefit from the constant stream of new medical literature, and how to differentiate good medical evidence from that which is inadequate or misleading. This edition includes numerous updates, several new chapters, and a greater emphasis on the role of patient preferences and preappraised resources. "The streamlined companion to the classic Users' guides to the medical literature ... fully updated and revised. This compact guide condenses the most clinically relevant content of the landmark Users' Guides to the Medical Literature to help you incorporate evidence-based medicine into your practice. You will learn the principles of evidence-based medicine, how your practice can benefit from the constant stream of new medical literature, and how to differentiate good medical evidence from bad. This edition includes several new chapters and a new emphasis on the role of patient preferences and preappraised resources ... Provided by publisher Fully updated to cover the new features and revamped interface of CorelDRAW X7, this official guide shows you how to create striking commercial graphics and exquisite artwork. Several step-by-step tutorials use all-new downloadable example files.