Ultrathin Electrochemical Chemo- And Biosensors: Technology And Performance (springer Series On Chemical Sensors And Biosensors)

Traditional biological sensors, based on enzymatic receptors and potentiometric or amperometric transducers are well reviewed and are nowadays even included extensively in many textbooks. The editors of this volume, the 2nd in the new Springer Series on Chemical and Biosensors, have focussed exclusively on alternative types of chemical and biological sensors or sensor-like structures. Special attention is given to sensor principles based on the use of linear or non-linear impedance spectroscopy. After self-assembled monolayers have become a viable technology for the immobilization of organic molecules on electrodes and for the formation of covalently stabilized receptor layers and even more sophisticated organic nano- and microstructures, this has led to the development of numerous analytical applications of impedometric sensor methods. These new and very promising types of sensors, their technology and performance in real world applications form the main topic of this book written by leading experts from around the world. Traditional biological sensors, based on enzymatic receptors and potentiometric or amperometric transducers are well reviewed and are nowadays even included extensively in many textbooks. The editors of this volume, the 2nd in the new Springer Series on Chemical and Biosensors, have focussed exclusively on alternative types of chemical and biological sensors or sensor-like structures. Special attention is given to sensor principles based on the use of linear or non-linear impedance spectroscopy. After self-assembled monolayers have become a viable technology for the immobilization of organic molecules on electrodes and for the formation of covalently stabilized receptor layers and even more sophisticated organic nano- and microstructures, this has led to the development of numerous analytical applications of impedometric sensor methods. These new and very promising types of sensors, their technology and performance in real world applications form the main topic of this book written by leading experts from around the world. TOC:Part 1: Receptors -B. Kramer and B. Hock: Antibodies For Biosensors.- Karsten Haupt: Molecularly Imprinted Polymers As Recognition Elements In Sensors.- Part 2: Impedometric And Amperometric Chemical And Biological Sensors - Helen Berney: Capacitance Affinity Biosensors.- Eugenil Katz and Itamar Willner: Immunosensors And DNA-Sensors Based On Impedance Specroscopy.- Michael J. Schoening: "Voltohmmetry" - A New Transducer Principle fo Electrochemical Sensors.- F. Lisdat: Electrochemical Sensors For The Detection Of Superoxide And Nitric Oxide - Two Biologically Important Radicals.-Part 3: Non-Invasive Electrical Monitoring Of Living Cells - Martin Brischwein, Helmut Grothe, Angela M. Otto, Christoph Stepper, Thomas Weyh and Bernhard Wolf: Living Cells on Chip: Bioanalytical Applications.- G. Farace and P. Vadgama: Bioanalytical Application Of Impedance Analysis: Transducing in Polymer Based Biosensors and Probes For Living Tissues.- Andreas Janshoff, Claudia Steinem, and Joachim Wegener: Non-Invasive Electrical Sensor Devices To Monitor Living Cells Online.-Part 4: Lipid Membranes As Biosensors - Wolfgang Knoll, Kenichi Morigaki, Renate Naumann, Barbara Sacca, Stefan Schiller and Eva-Kathrin Sinner: Functional Tethered Lipid Bilayer Membranes.- Valeri Sokolov and Vladimir Mirsky: Electrostatic Potentials of Bilayer Lipid Membranes: Basic Principles and Analytical Applications.- Tibor Hianik: Electrostriction Of Supported Lipid Membranes And Their Application In Biosensing.- K. Fendler, M. Klingenberg, G. Leblanc, J.J.H.H.M. Depont, B. Kelety, W. Dörner and E. Bamberg: Transport Proteins On Solid Supported Membranes: From Basic Research To Drug Discovery.- Part 1: Receptors: B. Kramer and B. Hock: Antibodies for Biosensors; Karsten Haupt: Molecularly Imprinted Polymers as Recognition Elements in Sensors Part 2: Impedometric and Amperometric Chemical and Biological Sensors: Helen Berney: Capacitance Affinity Biosensors; Eugenil Katz and Itamar Willner: Immunosensors and DNA-Sensors Based on Impedance Specroscopy; Michael J. Schoening: "Voltohmmetry" - A New Transducer Principle for Electrochemical Sensors; F. Lisdat: Electrochemical Sensors for the Detection of Superoxide and Nitric Oxide - Two Biologically Important Radicals Part 3: Non-Invasive Electrical Monitoring of Living Cells: Martin Brischwein, Helmut Grothe, Angela M. Otto, Christoph Stepper, Thomas Weyh, and Bernhard Wolf: Living Cells on Chip: Bioanalytical Applications; G. Farace and P. Vadgama: Bioanalytical Application of Impedance Analysis: Transducing in Polymer Based Biosensors and Probes for Living Tissues; Andreas Janshoff, Claudia Steinem, and Joachim Wegener: Non-Invasive Electrical Sensor Devices to Monitor Living Cells Online Part 4: Lipid Membranes as Biosensors: Wolfgang Knoll, Kenichi Morigaki, Renate Naumann, Barbara Sacca, Stefan Schiller, and Eva-Kathrin Sinner: Functional Tethered Lipid Bilayer Membranes; Valeri Sokolov and Vladimir Mirsky: Electrostatic Potentials of Bilayer Lipid Membranes: Basic Principles and Analytical Applications; Tibor Hianik: Electrostriction of Supported Lipid Membranes and their Application in Biosensing; K. Fendler, M. Klingenberg, G. Leblanc, J.J.H.H.M. Depont, B. Kelety, W. Dörner, and E. Bamberg: Transport Proteins on Solid Supported Membranes: From Basic Research to Drug Discovery. Front Matter....Pages I-XX Front Matter....Pages 1-1 Antibodies for Biosensors....Pages 3-22 Molecularly Imprinted Polymers as Recognition Elements in Sensors....Pages 23-39 Front Matter....Pages 41-41 Capacitance Affinity Biosensors....Pages 43-65 Immunosensors and DNA Sensors Based on Impedance Spectroscopy....Pages 67-116 “Voltohmmetry” — a New Transducer Principle for Electrochemical Sensors....Pages 117-140 Electrochemical Sensors for the Detection of Superoxide and Nitric Oxide — Two Biologically Important Radicals....Pages 141-155 Front Matter....Pages 157-157 Living Cells on Chip: Bioanalytical Applications....Pages 159-180 Bioanalytical Application of Impedance Analysis: Transducing in Polymer-Based Biosensors and Probes for Living Tissues....Pages 181-198 Noninvasive Electrical Sensor Devices to Monitor Living Cells Online....Pages 199-236 Front Matter....Pages 237-237 Functional Tethered Bilayer Lipid Membranes....Pages 239-253 Electrostatic Potentials of Bilayer Lipid Membranes: Basic Principles and Analytical Applications....Pages 255-291 Electrostriction of Supported Lipid Membranes and Their Application in Biosensing....Pages 293-330 Transport Proteins on Solid-Supported Membranes: From Basic Research to Drug Discovery....Pages 331-349 Back Matter....Pages 351-358

Traditional biological sensors, based on enzymatic receptors and potentiometric or amperometric transducers are well reviewed and are nowadays even included extensively in many textbooks. The editors of this volume, the 2nd in the new Springer Series on Chemical and Biosensors, have focussed exclusively on alternative types of chemical and biological sensors or sensor-like structures. Special attention is given to sensor principles based on the use of linear or non-linear impedance spectroscopy.
After self-assembled monolayers have become a viable technology for the immobilization of organic molecules on electrodes and for the formation of covalently stabilized receptor layers and even more sophisticated organic nano- and microstructures, this has led to the development of numerous analytical applications of impedometric sensor methods. These new and very promising types of sensors, their technology and performance in real world applications form the main topic of this book written by leading experts from around the world.

Biosensors take advantage of biomolecular interactions and have been used in the past most frequently in the field of clinical analysis and biochemistry [1-3].