UHMWPE Biomaterials Handbook - Ultra-High Molecular Weight Polyethylene in Total Joint Replacement and Medical Devices 2 ed.

This book describes the science, development, properties and application of of ultra-high molecular weight polyethylene (UHMWPE) used in artificial joints. This material is currently used in 1.4 million patients around the world every year for use in the hip, knee, upper extremities, and spine. Since the publication of the 1st edition there have been major advances in the development and clinical adoption of highly crosslinked UHMWPE for hip and knee replacement. There has also been a major international effort to introduce Vitamin E stabilized UHMWPE for patients. The accumulated knowledge on these two classes of materials are a key feature of the 2nd edition, along with an additional 19 additional chapters providing coverage of the key engineering aspects (biomechanical and materials science) and clinical/biological performance of UHMWPE, providing a more complete reference for industrial and academic materials specialists, and for surgeons and clinicians who require an understanding of the biomaterials properties of UHMWPE to work successfully on patient applications. * The UHMWPE Handbook is the comprehensive reference for professionals, researchers, and clinicians working with biomaterials technologies for joint replacement * New to this edition: 19 new chapters keep readers up to date with this fast moving topic, including a new section on UHMWPE biomaterials; highly crosslinked UHMWPE for hip and knee replacement; Vitamin E stabilized UHMWPE for patients; clinical performance, tribology an biologic interaction of UHMWPE * State-of-the-art coverage of UHMWPE technology, orthopedic applications, biomaterial characterisation and engineering aspects from recognised leaders in the field Content: Copyright Page , Page iv Dedication , Page v Foreword , Pages xvii-xviii , Steven Kurtz Contributors , Page xix Chapter 1 - A Primer on UHMWPE , Pages 1-6 , Steven M. Kurtz Chapter 2 - From Ethylene Gas to UHMWPE Component: The Process of Producing Orthopedic Implants , Pages 7-19 , Steven M. Kurtz Chapter 3 - Packaging and Sterilization of UHMWPE , Pages 21-30 , Steven M. Kurtz Chapter 4 - The Origins of UHMWPE in Total Hip Arthroplasty , Pages 31-41 , Steven M. Kurtz Chapter 5 - The Clinical Performance of UHMWPE in Hip Replacements , Pages 43-53 , Steven M. Kurtz Chapter 6 - Contemporary Total Hip Arthroplasty: Hard-on-Hard Bearings and Highly Crosslinked UHMWPE , Pages 55-79 , Steven M. Kurtz, Kevin Ong Chapter 7 - The Origins and Adaptations of UHMWPE for Knee Replacements , Pages 81-95 , Steven M. Kurtz Chapter 8 - The Clinical Performance of UHMWPE in Knee Replacements , Pages 97-116 , Steven M. Kurtz Chapter 9 - The Clinical Performance of UHMWPE in Shoulder Replacements , Pages 117-135 , Stefan M. Gabriel Chapter 10 - The Clinical Performance of UHMWPE in Elbow Replacements , Pages 137-152 , Judd S. Day Chapter 11 - Applications of UHMWPE in Total Ankle Replacements , Pages 153-169 , Allyson Ianuzzi, Chimba Mkandawire Chapter 12 - The Clinical Performance of UHMWPE in the Spine , Pages 171-195 , Steven M. Kurtz, Marta L. Villarraga, Allyson Ianuzzi Chapter 13 - Highly Crosslinked and Melted UHMWPE , Pages 197-204 , Orhun K. Muratoglu Chapter 14 - Highly Crosslinked and Annealed UHMWPE , Pages 205-219 , John H. Dumbleton, Aiguo Wang, Kate Sutton, Michael T. Manley Chapter 15 - Highly Crosslinked UHMWPE Doped with Vitamin E , Pages 221-236 , Ebru Oral, Orhun K. Muratoglu Chapter 16 - Vitamin-E-Blended UHMWPE Biomaterials , Pages 237-247 , Steven Kurtz, Pierangiola Bracco, Luigi Costa Chapter 17 - Composite UHMWPE Biomaterials and Fibers , Pages 249-258 , Steven M. Kurtz Chapter 18 - UHMWPE/Hyaluronan Microcomposite Biomaterials , Pages 259-276 , Susan P. James, Rachael (Kurkowski) Oldinski, Min Zhang, Herb Schwartz Chapter 19 - High Pressure Crystallized UHMWPEs , Pages 277-289 , Anuj Bellare, Steven M. Kurtz Chapter 20 - Compendium of Highly Crosslinked UHMWPEs , Pages 291-308 , Steven M. Kurtz Chapter 21 - Mechanisms of Crosslinking, Oxidative Degradation and Stabilization of UHMWPE , Pages 309-323 , Luigi Costa, Pierangiola Bracco Chapter 22 - In Vivo Oxidation of UHMWPE , Pages 325-340 , Steven M. Kurtz Chapter 23 - Pathophysiologic Reactions to UHMWPE Wear Particles , Pages 341-353 , Marla J. Steinbeck, Ryan M. Baxter, Theresa A. Freeman Chapter 24 - Characterization of Physical, Chemical, and Mechanical Properties of UHMWPE , Pages 355-368 , Stephen Spiegelberg Chapter 25 - Tribological Assessment of UHMWPE in the Hip , Pages 369-379 , Aaron Essner, Aiguo Wang Chapter 26 - Tribological Assessment of UHMWPE in the Knee , Pages 381-408 , Hani Haider Chapter 27 - Characterization of UHMWPE Wear Particles , Pages 409-422 , Joanne L.Tipper, Laura Richards, Eileen Ingham, John Fisher Chapter 28 - Clinical Surveillance of UHMWPE Using Radiographic Methods , Pages 423-432 , Charles R. Bragdon Chapter 29 - ESR Insights into Macroradicals in UHMWPE , Pages 433-450 , M. Shah Jahan Chapter 30 - Fatigue and Fracture of UHMWPE , Pages 451-472 , Francisco J. Medel, Jevan Furmanski Chapter 31 - Development and Application of the Notched Tensile Test to UHMWPE , Pages 473-483 , Michael C. Sobieraj, Clare M. Rimnac Chapter 32 - Development and Application of the Small Punch Test to UHMWPE , Pages 485-496 , Avram A. Edidin Chapter 33 - Nano- and Microindentation Testing of UHMWPE , Pages 497-509 , Jeremy L. Gilbert, James D. Wernle Chapter 34 - MicroCT Analysis of Wear and Damage in UHMWPE , Pages 511-518 , Dan MacDonald, Anton Bowden, Steven M. Kurtz Chapter 35 - Computer Modeling and Simulation of UHMWPE , Pages 519-532 , Anton E. Bowden, Erin Oneida, Jorgen Bergström Index , Pages 533-543 Suitable for professionals, researchers, and clinicians working with biomaterials technologies for joint replacement, this book describes the science, development, properties and application of of ultra-high molecular weight polyethylene (UHMWPE) used in artificial joints.