Tunneling in Biological Systems : A Colloquium of the Johnson Research Foundation

Tunneling in Biological Systems focuses on the low temperature electron transport that reveals a quantum-mechanical effect called “tunneling.” This book discusses the tunneling in physical systems; detection of molecular vibrations with electron tunneling; chemical-rate theory of small-polaron hopping; and experimental approaches to electronic coupling in metal ion redox systems. The Faraday rotation and photoconductivity of photosynthetic structures at microwave frequencies; dynamics of electron transport in macromolecules; and electron transfer reactions in cytochrome oxidase are also elaborated. This text likewise covers the kinetic evidence for electron tunneling in solution; specificity and control in biological systems; molecular tunneling in heme proteins; and ligand binding. This publication is valuable to students and researchers interested in the physics of biological and medical problems. Content: Johnson Research Foundation Colloquia , Page ii Front Matter , Page iii Copyright , Page iv LIST OF CONTRIBUTORS , Pages xiii-xvi PREFACE , Pages xvii-xviii MY TUNNELING EXPERIENCES , Pages 3-8 , W.F. Libby INTRODUCTORY COMMENTS , Pages 9-16 , J.R. Schrieffer TUNNELING IN PHYSICAL SYSTEMS , Pages 17-29 , R.C. Dynes CONCEPTS IN QUANTUM MECHANICAL TUNNELING IN SYSTEMS OF BIOLOGICAL AND CHEMICAL INTEREST , Pages 31-66 , Charles B. Duke DETECTION OF MOLECULAR VIBRATIONS WITH ELECTRON TUNNELING , Pages 67-76 , Robert V. Coleman TUNNELING IN NETWORK MODELS OF MOLECULAR CHAINS , Pages 77-90 , Aaron Budgor LOCALIZED AND DELOCALIZED TUNNELING STATES , Pages 91-94 , Robert S. Knox General Discussion : FORMULATIONS OF THEORY , Pages 95-105 ELECTRON AND NUCLEAR TUNNELING IN CHEMICAL AND BIOLOGICAL SYSTEMS , Pages 109-127 , R.A. Marcus CHEMICAL-RATE THEORY OF SMALL-POLARON HOPPING , Pages 129-138 , T. Holstein A GENERAL THEORETICAL APPROACH TO TUNNELING TRANSFER AND DISSOCIATION , Pages 139-144 , P.H. Cribb, S. Nordholm, N.S. Hush A QUANTUM THEORY OF LOW-TEMPERATURE CHEMICAL AND BIOLOGICAL RATE PROCESSES IN CONDENSED MEDIA , Pages 145-171 , R.R. Dogonadze, A.M. Kuznetsov, M.G. Zakaraya, J. Ulstrup EXPERIMENTAL APPROACHES TO ELECTRONIC COUPLING IN METAL ION REDOX SYSTEMS , Pages 173-199 , Henry Taube ELECTRON TRANSFER REACTIONS OF METAL COMPLEXES IN SOLUTION , Pages 201-227 , Norman Sutin ELECTRON TRANSFER PROPERTIES OF THE IMIDAZOLATE ANION , Pages 229-236 , Stephan S. Isied, Christa Kuehn ELECTRON TRANSFER IN (NH 3 ) 5 Ru(III)-4-ALKYLPYRIDINE-Cu(I) BINUCLEAR IONS , Pages 237-241 , Kenneth A. Norton, Leslie G. Hulett, David J. Halko, James K. Hurst ELECTRON TUNNELING AFTER RADIOLYSIS , Pages 243-268 , Brian Brocklehurst TUNNELING DISTANCES AND EXOTHERMIC RATE RESTRICTIONS IN ELECTRON TRANSFER REACTIONS , Pages 269-280 , James V. Beitz, John R. Miller General Discussion : ELECTRON VS. NUCLEAR TUNNELING , Pages 281-294 General Discussion : ADIABATICITY , Pages 295-299 INTRODUCTION TO BIOLOGICAL ASPECTS , Pages 303-316 , Don DeVault CYTOCHROME-REACTION CENTER-QUINONE INTERACTIONS: MODELS FOR BIOLOGICAL ELECTRON TRANSFER , Pages 319-354 , P. Leslie Dutton, John S. Leigh Jr., Roger C. Prince, David M. Tiede ELECTRON TRANSFER BETWEEN c -TYPE CYTOCHROMES AND HIGH POTENTIAL IRON-SULFUR PROTEINS , Pages 355-362 , M.A. Cusanovich, I.A. Mizrahi AN APPLICATION OF ELECTRON TRANSFER THEORY TO A PROBLEM IN CHLOROPLAST MEMBRANE TOPOGRAPHY , Pages 363-370 , W.A. Cramer, J. Whitmarsh ELECTRON TUNNELING IN PHOTOSYSTEM-I CHARGE RECOMBINATION AT LOW TEMPERATURES , Pages 371-376 , Bacon Ke, Sandor Demeter, K.I. Zamaraev, R.F. Khairutdinov SOME DATA OF POSSIBLE RELEVANCE TO TUNNELING IN PHOTOSYNTHETIC REACTION CENTERS , Pages 377-386 , Roderick K. Clayton THE EFFECTS OF HIGH HYDROSTATIC PRESSURE ON LIGHT-INDUCED ELECTRON TRANSFER AND PROTON BINDING IN CHROMATIUM , Pages 387-403 , Britton Chance, Don DeVault, Akira Tasaki, J. Phillip Thornber FARADAY ROTATION AND PHOTOCONDUCTIVITY OF PHOTOSYNTHETIC STRUCTURES AT MICROWAVE FREQUENCIES , Pages 405-416 , R.A. Bogomolni, M.P. Klein NONADIABATIC ELECTRON TUNNELING: IMPLICATIONS FOR BACTERIAL PHOTOSYNTHESIS AND FOR CRITICAL PHYSICAL TESTS OF THE MECHANISM , Pages 417-432 , J.J. Hopfield DYNAMICS OF ELECTRON TRANSPORT IN MACROMOLECULES , Pages 433-438 , M.J. Potasek General Discussion : TEMPERATURE DEPENDENCE , Pages 439-450 MITOCHONDRIAL ELECTRON TRANSFER AT PHOSPHORYLATION SITES 2 AND 3 , Pages 453-472 , Maria Erecinska ELECTRON TRANSPORT IN THE SUCCINATE-UBIQUINONE SEGMENT OF THE RESPIRATORY CHAIN , Pages 473-482 , J.C. Salerno, T. Ohnishi ELECTRON TRANSFER REACTIONS IN CYTOCHROME OXIDASE , Pages 483-511 , Britton Chance, Carlo Saronio, John S. Leigh Jr., Alan Waring DEFINITION OF THE SURFACE OF CYTOCHROME c INTERACTING WITH CYTOCHROME OXIDASE , Pages 513-521 , Shelagh Ferguson-Miller, David L. Brautigan, Emanuel Margoliash STRUCTURE/FUNCTION RELATIONSHIPS IN BIOLOGICAL ELECTRON TRANSPORT PROTEINS , Pages 523-541 , F.R. Salemme General Discussion : CYTOCHROME c AND SOME OTHER BIOLOGICAL REDOX MOLECULES , Pages 543-557 CONFORMATIONAL DISTRIBUTION AND VIBRONIC COUPLING IN THE BLUE COPPER-CONTAINING PROTEIN AZURIN , Pages 561-568 , Arthur S. Brill OVERALL CHARGE CONTROL OF THE IONIC STRENGTH EFFECTS UPON THE REDOX KINETICS OF SMALL MOLECULE-PROTEIN AND PROTEIN-PROTEIN REACTIONS , Pages 569-574 , Benjamin A. Feinberg, George Aprahamian, Laura Neeck, Michael D. Ryan, Jing-Fong Wei THE ENERGY TRANSFORMING FUNCTION ASSOCIATED WITH ELECTRON TRANSFER REACTIONS IN BIOLOGICAL SYSTEMS , Pages 575-580 , Bo Cartling, Anders Ehrenberg KINETIC EVIDENCE FOR ELECTRON TUNNELING IN SOLUTION , Pages 581-587 , S.G. Ballard, D. Mauzerall FERMI-LEVEL MATCHING: A POSSIBLE CONDITION IN REDOX ENZYME SPECIFICITY , Pages 589-593 , Shang J. Yao General Discussion : DISTANCES , Pages 595-603 SPECIFICITY AND CONTROL IN BIOLOGICAL SYSTEMS , Pages 605-607 , J. Ulstrup General Discussion : BIOLOGICAL SPECIFICITY AND CONTROL , Pages 609-623 MOLECULAR TUNNELING IN HEME PROTEINS , Pages 627-649 , Hans Frauenfelder HEME LIGAND CONFIGURATION IN PHOTODISSOCIABLE FERROUS MYOGLOBIN COMPLEXES , Pages 651-660 , H.A. Glick, R.S. Danziger, M.W. Makinen, A.K. Churg, R.A. Houtchens, W.S. Caughey General Discussion : LIGAND BINDING , Pages 661-662 QUANTUM CHEMICAL REACTIVITY NEAR ABSOLUTE ZERO: BIOLOGICAL, CHEMICAL AND ASTROPHYSICAL ASPECTS , Pages 663-711 , Vitalii I. Goldanskii NEW METHODS FOR EXPLORING TUNNELING PHENOMENA , Pages 715-719 , Vitalii I. Goldanskii General Discussion : EXPERIMENTAL TECHNIQUES , Pages 721-728 MAGNETIC INTERACTIONS AND ELECTRON TRANSFER KINETICS OF THE REDUCED INTERMEDIATE ACCEPTOR IN REACTION CENTERS (RCs) OF RHODOPSEUDOMONAS SPHAEROIDES R-26. EVIDENCE FOR THERMALLY INDUCED TUNNELING , Pages 729-743 , M.Y. Okamura, D.R. Fredkin, R.A. Isaacson, G. Feher SUBJECT INDEX , Pages 745-758 Edited By Britton Chance ... [et Al.]. Proceedings Of A Symposium ... Held In Philadelphia, Pennsylvania On November 3-5, 1977. Includes Bibliographies And Index.