Tumor Microenvironment: Hematopoietic Cells – Part B (Advances in Experimental Medicine and Biology Book 1273)

Revealing essential roles of the tumor microenvironment in cancer progression, this book focuses on the role of hematopoietic components of the tumor microenvironment. Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include eosinophils, NK cells, γδ T cells, regulatory T Cells, Langerhans cells, hematopoietic stem cells, Mast cells, B cells and Microglia, and more. Taken alongside its companion volumes, __Tumor Microenvironment: Hematopoietic Cells – Part B__ updates us on what we know about various aspects of the tumor microenvironment as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment. Front Matter ....Pages i-xiv Eosinophils in the Tumor Microenvironment (Fabrizio Mattei, Sara Andreone, Giancarlo Marone, Adriana Rosa Gambardella, Stefania Loffredo, Gilda Varricchi et al.)....Pages 1-28 Dendritic Cells in the Tumor Microenvironment (Karan Kohli, Venu G. Pillarisetty)....Pages 29-38 Resident Memory T Cells in the Tumor Microenvironment (Jason B. Williams, Thomas S. Kupper)....Pages 39-68 NK Cells in the Tumor Microenvironment (Camille Guillerey)....Pages 69-90 γδ T Cells in Tumor Microenvironment (Caroline Imbert, Daniel Olive)....Pages 91-104 Regulatory T Cells in the Tumor Microenvironment (Rebekah E. Dadey, Creg J. Workman, Dario A. A. Vignali)....Pages 105-134 The Hematopoietic Microenvironment in Myeloproliferative Neoplasms: The Interplay Between Nature (Stem Cells) and Nurture (the Niche) (Huichun Zhan, Kenneth Kaushansky)....Pages 135-145 Novel Concepts: Langerhans Cells in the Tumour Microenvironment (Aarthi Rajesh, Merilyn Hibma)....Pages 147-158 Mast Cells in the Tumor Microenvironment (Angélica Aponte-López, Samira Muñoz-Cruz)....Pages 159-173 B Cells in the Gastrointestinal Tumor Microenvironment with a Focus on Pancreatic Cancer: Opportunities for Precision Medicine? (Dário Ligeiro, Martin Rao, Andreia Maia, Mireia Castillo, Antonio Beltran, Markus Maeurer)....Pages 175-195 Microglia in the Brain Tumor Microenvironment (Allison P. Cole, Eric Hoffmeyer, Senthilnath Lakshmana Chetty, Joselyn Cruz-Cruz, Forrest Hamrick, Osama Youssef et al.)....Pages 197-208 Back Matter ....Pages 209-215 "Revealing essential roles of the tumor microenvironment in cancer progression, this book focuses on the role of hematopoietic components of the tumor microenvironment. Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include eosinophils, NK cells, [gamma[ [delta] T cells, regulatory T Cells, Langerhans cells, hematopoietic stem cells, Mast cells, B cells and Microglia, and more. Taken alongside its companion volumes, Tumor Microenvironment: Hematopoietic Cells - Part B updates us on what we know about various aspects of the tumor microenvironment as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment"--Publisher's description This book provides a comprehensive overview of the latest research on the molecular players in the tumor microenvironment, including Cathepsin D, galectins, iron, oxygen, Phospholipase D1, leptin, extracellular vesicles, and more.