Trisomy 21: An International Symposium Convento Delle Clarisse, Rapallo, Italy, November 8 - 10, 1979 (human Genetics Supplementa)

## i. Br., Federal Republic of Germany The organizers wish to express their thanks to the Sindaco of Rapallo for the generous hospitality and to Dr. G. Gimelli for assistance with the organization. Front Matter....Pages I-VI Introduction to the Symposium....Pages 1-1 Clinical Aspects of Down’s Syndrome from Infancy to Adult Life....Pages 3-31 Down’s Syndrome: Problems of Immunodeficiency....Pages 33-39 Dermatoglyphic Peculiarities in Down’s Syndrome Detection of Mosaicism and Balanced Translocation Carriers....Pages 41-56 Pathology of Trisomy 21 — with Particular Reference to Persistent Common Atrioventricular Canal of the Heart....Pages 57-73 Down’s Syndrome and the Family....Pages 75-80 Asking for a Prenatal Diagnosis After the Birth of a Child with Down’s Syndrome....Pages 81-90 Vingt Ans Après....Pages 91-101 Nondisjunction....Pages 103-143 Experiments on Chiasmata and Nondisjunction in Mice....Pages 145-146 Gene Mapping and Chromosome 21: History and Methodology....Pages 147-153 Functional Implications of Gene Dosage Effects in Trisomy 21....Pages 155-172 Structural Variation of Chromosome 21 and Symptoms of Down’s Syndrome....Pages 173-182 Prenatal Losses of Trisomy 21....Pages 183-193 Incidence of Down’s Syndrome in Sweden During the Years 1968–1977....Pages 195-210 Epidemiology of Trisomy 21: Population, Peri- and Antenatal Data....Pages 211-226 Back Matter....Pages 227-265 Organizers, G.r. Burgio, M. Fraccaro, And L. Tiepolo ; Editors, G.r. Burgio ... [et Al.] ; Contributors, G. Anneren ... [et Al.]. Includes Bibliographies And Indexes.