Treatment of Bone and Soft Tissue Sarcomas (Recent Results in Cancer Research, 179)

Bone and soft tissue sarcomas represent only about 2 per cent of all malignancies; however, their treatment - with the goal of curing the patient while preserving the functionality of the affected body part - can, unlike other malignancies, only be successful with therapy concepts devised by interdisciplinary teams. This volume provides an extensive up-to-date overview of the specific diagnostics and current treatment standards of these rare entities, presenting the various limb-sparing modalities for patients with bone and soft tissue sarcomas with special regard to innovative reconstructive options. The evaluation of quality of life based on validated scores and the individual methods of coping with the illness through creative artistic projects are also acknowledged and integrated in the whole concept Front Matter....Pages i-xxii Biopsy of Bone and Soft Tissue Tumours: Hints and Hazards....Pages 3-10 The Role of Intra-operative Pathological Evaluation in the Management of Musculoskeletal Tumours....Pages 11-24 Sentinel Node Biopsy in Soft Tissue Sarcome....Pages 25-36 Modular Endoprosthetic Reconstruction in Malignant Bone Tumors: Indications and Limits....Pages 39-50 Allograft Reconstruction in Malignant Bone Tumors: Indications and Limits....Pages 51-58 Expandable Endoprostheses in Malignant Bone Tumors in Children: Indications and Limitations....Pages 59-73 The Long-Term Risks of Infection and Amputation with Limb Salvage Surgery Using Endoprostheses....Pages 75-84 Reconstruction of the Pelvis After Resection of Malignant Bone Tumours in Children and Adolescents....Pages 85-111 Methods of Biological Reconstruction for Bone Sarcoma: Indications and Limits....Pages 113-140 Bone Sarcoma of the Spine....Pages 141-167 Computer-Assisted Pelvic Tumor Resection: Fields of Application, Limits, and Perspectives....Pages 169-182 Pulmonary Metastasectomy for Osteosarcoma: Is It Justified?....Pages 183-208 Standardized Approach to the Treatment of Adult Soft Tissue Sarcoma of the Extremities....Pages 211-228 Evaluating Surgery Quality in Soft Tissue Sarcoma....Pages 229-242 Peripheral Nerve Considerations in the Management of Extremity Soft Tissue Sarcomas....Pages 243-256 Isolated Limb Perfusion with TNF-α and Melphalan in Locally Advanced Soft Tissue Sarcomas of the Extremities....Pages 257-270 Management of Locally Recurrent Soft Tissue Sarcoma after Prior Surgery and Radiation Therapy....Pages 271-283 Management of Vascular Involvement in Extremity Soft Tissue Sarcoma....Pages 285-299 Current Concepts in the Management of Retroperitoneal Soft Tissue Sarcoma....Pages 301-319 Pulmonary Metastasectomy for Soft Tissue Sarcomas: Is It Justified?....Pages 321-336 Quality of Life (QOL) in Patients with Osteosarcoma....Pages 339-344 Clinical Trials in Osteosarcoma Treatment: Patients' Perspective Through Art....Pages 345-361 This Volume Provides An Up-to-date Overview Of The Specific Diagnostics And Current Treatment Standards Of Bone And Soft Tissue Sarcomas, Presenting The Various Limb-sparing Modalities For Patients With Bone And Soft Tissue Sarcomas With Special Regard To Innovative Reconstructive Options. Per-ulf Tunn (ed.). Includes Bibliographical References.