Transabdominal Fine-Needle Aspiration Biopsy: A Color Atlas and Monograph, 2nd edition

• Over 1,350 illustrations in 350 innovative composite figures designed to teach general pathologists the cytologic approach and cytologists the histologic basis for cytologic criteria• CD-ROM containing high resolution composite images that can be enlarged to the size of computer screen and detailed legends with clinical presentation, cytologic clues with different stains from low to high magnification as well as the mistakes made and lessons learned• Pathologic entities are arranged in the current classifications used by surgical pathologists so that they can translate their experience in histopathology to cytopathology• New classifications of tumors based on advances in cytogenetic and molecular evidence and all new illustrated cases from G C H Yang's collection• A new chapter on gynecologic tumors has been added. The chapter on malignant lymphoma has been completely rewritten to incorporate current WHO classifications. New tumors discovered in the past 16 years and new classifications of adrenal, kidney, liver and pancreatic tumors have been addedThe objective of this book is to share authors' combined 30 years' experience in the fine-needle aspiration biopsy diagnosis of organs beneath the diaphragm with general pathologists. Starting from the basics, this book progresses to in-depth cytomorphologic analysis with histologic and immunohistochemical confirmation of specific entities. Cytohistological correlation is emphasized by using composite images from either resected tumor or the cell block whenever possible. In addition, ultrastructural basis of cytological features is emphasized. Both cytology and electron microscopy classify tumors by meticulously analyzing the cytoplasmic features and cell junctions of scanty sample. Every histopathology entity should have a counterpart in cytopathology, since both derive from the same entity undergoing the same pathological process. The difference is in the artifacts; thus an attempt was made to explain the artifacts of aspiration cytology so that histopathologists may understand the cytologic approach and learn to interpret aspiration cytology with confidence. 1. Introduction. History. Indications and contraindications. Advantages. Complications. Reliability. Endoscopic ultrasound-guided fine needle aspiration biopsy. Conclusions -- 2. Procedures and techniques. Localization methods. Aspiration biopsy instruments and material. Techniques of transabdominal aspiration biopsy. Processing of the aspirated material. Procedure of direct smear preparation. Ultrafast Papanicolaou stain. Cell block preparation. False-negative results -- 3. Approaches to the interpretation of transabdominal fine-needle aspiration biopsy. Team approach to diagnosis. Cytologic criteria for the interpretation of aspiration biopsy. Pitfalls and limitations -- 4. The liver. Normal cellular components. Nonneoplastic mass lesions. Benign mesenchymal tumors. Nodular hepatocellular lesions. Tumors of intrahepatic bile duct. Angiosarcoma. Epitheloid hemangioendothelioma. Embryonal (undifferentiation) sarcoma. Metastatic tumors -- 5. The pancreas. Normal cellular components. Pancreatitis. Tumors of the pancreas -- 6. Mass lesions of the kidney. Normal cellular components. Nonneoplastic mass lesions. Benign mesenchymal tumors. Classification of renal epithelial tumors. Malignant tumors -- 7. Normal cellular components. Nonneoplastic lesions. Adrenocortical nodules. Tumors of the adrenal cortex. Tumors of the adrenal medulla -- 8. Primary retroperitoneal mass lesions. Nonneoplastic mass lesions. Idiopathic retroperitoneal fibrosis. Sarcomas. Neurogenic tumors. Germ cell tumors. Malignant lymphomas. Other tumors -- 9. Gynecologic tumors. Endometriosis. Uterine tumors. Myometrial tumors. Cervix. Fallopian tube cancers. Ovarian cancers. Broad ligament tumors. Potential for aspiration biopsy of ovarian masses -- 10. Intraperitoneal masses. Tumors of the gastrointestinal tract -- 11. Malignant lymphomas. Classification of non-Hodgkin lymphomas. Current concept and developmentof lymphomas. General cytologic criteria for the diagnosis of non-Hodgkin lymphomas. Cytologic presentations of non-Hodgkin lymphomas. B-cell neoplasms. T-cell neoplasms. Leukemic or disseminated lymphoma. Extranodal T/NK cell lymphomas. Nodal T/NK cell lymphomas. Hodgkin lymphoma. Histiocytic and dendritic neoplasms -- 12. Immunomarkers for transabdominal aspiration biopsy. Immunohistochemical staining for aspiration biopsy. Avidin-biotin-immunoperoxidase staining procedure for aspiration preparations. Technical problems in immunohistochemical staining for aspiration preparations. Useful tumor markers for the interpretation of transabdominal aspiration biopsy specimens. Frequently ordered immunomarkers. Commercially available antibodies Dedication; Foreword to the Second Edition; Preface to Second Edition; Preface to First Edition; Contents; 1. INTRODUCTION; 2. PROCEDURES AND TECHNIQUES; 3. APPROACHES TO THE INTERPRETATION OF TRANSABDOMINAL FINE-NEEDLE ASPIRATION BIOPSY; 4. THE LIVER; 5. THE PANCREAS; 6. MASS LESIONS OF THE KIDNEY; 7. PRIMARY LESIONS OF THE ADRENAL GLAND; 8. PRIMARY RETROPERITONEAL MASS LESIONS; 9. GYNECOLOGIC TUMORS; 10. INTRAPERITONEAL MASSES; 11. MALIGNANT LYMPHOMAS; 12. IMMUNOMARKERS FOR TRANSABDOMINAL ASPIRATION BIOPSY; Index; Features over 1,350 illustrations in 350 figures designed to teach general pathologists the cytologic approach and cytologists the histologic basis for cytologic criteria. Starting from the basics, this book progresses to cytomorphologic analysis with histologic and immunohistochemical confirmation of specific entities.