Total synthesis of bioactive natural products

Total Synthesis of Bioactive Natural Products provides step-by-step guidelines for effectively synthesizing the most promising bioactive agents from a broad range of natural products. Beginning with a concise background that outlines the benefits and challenges faced in effective synthesis, the book goes on to provide individual outlines for approximately 100 of the most promising bioactive agents. Taking a logical, user-friendly approach, the systematic name, compound class, structure, natural source, pharmaceutical potential and synthetic routes for each structure are detailed, with clear illustrations throughout, making this book an essential and practical guide for anyone working with both synthesis and natural products. Read more... Abstract: Total Synthesis of Bioactive Natural Products provides step-by-step guidelines for effectively synthesizing the most promising bioactive agents from a broad range of natural products. Beginning with a concise background that outlines the benefits and challenges faced in effective synthesis, the book goes on to provide individual outlines for approximately 100 of the most promising bioactive agents. Taking a logical, user-friendly approach, the systematic name, compound class, structure, natural source, pharmaceutical potential and synthetic routes for each structure are detailed, with clear illustrations throughout, making this book an essential and practical guide for anyone working with both synthesis and natural products Content: Front Cover Total Synthesis of Bioactive Natural Products Copyright Dedication Contents Foreword Preface References Chapter One: Aeruginosins 298-A and B References Chapter Two: Ageladine A References Chapter Three: (+)-Ainsliadimer A References Chapter Four: ( -- )-Aiphanol References Chapter Five: (+)-Amphidinolide T1 References Chapter Six: Ancistroealaine A and Ancistrotanzanine B References Chapter Seven: ( -- )-Andrographolide References Chapter Eight: Anolignan A References Chapter Nine: Anolignan B References Chapter Ten: Antrocamphin A References Chapter Eleven: Arenamide AReferences Chapter Twelve: Atroviridin References Chapter Thirteen: Bauhinoxepin J References Chapter Fourteen: Beta-Lapachone References Chapter Fifteen: Bombykol References Chapter Sixteen: Bulbophylol-B References Chapter Seventeen: Caminoside A References Chapter Eighteen: (+)-Chaetocin References Chapter Nineteen: Ciliatamides A and B References Chapter Twenty: Cylindol A References Chapter Twenty One: Daedalin A References Chapter Twenty Two: 6-Deoxypladienolide D References Chapter Forty Seven: Paecilomycine AReferences Chapter Forty Eight: Pochonin A References Chapter Forty Nine: Rhinacanthin A References Chapter Fifty: Rubriflordilactone A References Chapter Fifty One: (+)-Sattazolin References Chapter Fifty Two: Somocystinamide A References Chapter Fifty Three: ( -- )-Stagonolide A References Chapter Fifty Four: (±)-Steenkrotin A References Chapter Fifty Five: Thiaplakortone A and Its Semisynthetic Derivatives References Chapter Fifty Six: Vinigrol References Chapter Fifty Seven: Withaferin A References Chapter Fifty Eight: Withanolide A

Total Synthesis of Bioactive Natural Products provides step-by-step guidelines for effectively synthesizing the most promising bioactive agents from a broad range of natural products. Beginning with a concise background that outlines the benefits and challenges faced in effective synthesis, the book goes on to provide individual outlines for approximately 100 of the most promising bioactive agents. Taking a logical, user-friendly approach, the systematic name, compound class, structure, natural source, pharmaceutical potential and synthetic routes for each structure are detailed, with clear illustrations throughout, making this book an essential and practical guide for anyone working with both synthesis and natural products.

• Provides individual outlines for the total synthesis of approximately 100 bioactive natural molecules
• Outlines each step of the process in detail, with full experimental information supported by extensive schemes
• Includes retrosynthetic analyses, reaction sequences and stereochemically crucial steps for each molecule