Time, love, memory: a great biologist and this quest for the origins of behaviour

From the author of the Pulitzer Prize-winning **The Beak of the Finch,** the riveting story of a biologist's search for the foundations of behavior.Looking over the shoulder of some of the premier scientists in the filed, Jonathan Weiner takes us into their laboratories to show us how pieces of DNA actually shape behavior. He focuses on the work of Seymour Benzer, who, decades ago, with James Watson and Francis Crick, helped to crack the genetic code. Then, in a simple experiment using a few test tubes, a light bulb, and 100 fruit flies, Benzer invented the genetic dissection of behavior. Now we see how he and his students find and study genes that build our inner clocks, genes that shape the way we love, and genes that decide what we can (or cannot) remember. These breakthroughs help explain secrets of human behavior and may lead to advance treatments for behavioral disorders ranging from rage to autism to schizophrenia.In a narrative that sweeps from the first years of the century to the present, Weiner makes the process of scientific discovery and understanding almost tangible on the page. **Time, Love, Memory** is a brilliant work of scientific reportage. The Beak of the Finch tells the story of two Princeton University scientists - evolutionary biologists - engaged in an extraordinary investigation. They are watching, and recording, evolution as it is occurring - now - among the very species of Galapagos finches that inspired Darwin's early musings on the origin of species. They are studying the evolutionary process not through the cryptic medium of fossils but in real time, in the wild, in the flesh. The finches that Darwin took from Galapagos at the time of his voyage on the Beagle led to his first veiled hints about his revolutionary theory. But Darwin himself never saw evolution as Peter and Rosemary Grant have been seeing it - in the act of happening. For more than twenty years they have been monitoring generation after generation of finches on the island of Daphne Major - measuring, weighing, observing, tracking, analyzing on computers their struggle for existence. We see the Grants at work on the island among the thousands of living, nesting, hatching, growing birds whose world and lives are the Grants' primary laboratory. We explore the special circumstances that make the Galapagos archipelago a paradise for evolutionary research: an isolated population of birds that cannot easily fly away and mate with other populations, islands that are the tips of young volcanoes and thus still rapidly evolving as does the life that they support, a food supply changing radically in response to radical variations of climate - so that in a brief span of time the Grants can see the beak of the finch adapt. And we watch the Grants' team observe evolution at a level that was totally inaccessible to Darwin: the molecular level, as the DNA in the blood samples taken from the birds reveals evolutionary change. Here, brilliantly and lucidly recounted - with important implications for our own day, when man's alterations of the environment are speeding the rate of evolutionary changes - is a scientific enterprise in the grand m

On a remote outpost of the Galapagos, where Darwin received his first inklings of the theory of evolution, two scientists, Peter and Rosemary Grant, have spent 20 years measuring the beaks of generations of finches--to prove that Darwin did not know the strength of this own theory. Spark(s) not just the intellect, but the imagination.--Washington Post Book World. 50 illustrations. Map.

From the author of the Pulitzer Prize-winning The Beak of the Finch, the riveting story of a biologist's search for the foundations of behavior. Looking over the shoulder of some of the premier scientists in the filed, Jonathan Weiner takes us into their laboratories to show us how pieces of DNA actually shape behavior. He focuses on the work of Seymour Benzer, who, decades ago, with James Watson and Francis Crick, helped to crack the genetic code. Then, in a simple experiment using a few test tubes, a light bulb, and 100 fruit flies, Benzer invented the genetic dissection of behavior. Now we see how he and his students find and study genes that build our inner clocks, genes that shape the way we love, and genes that decide what we can (or cannot) remember. These breakthroughs help explain secrets of human behavior and may lead to advance treatments for behavioral disorders ranging from rage to autism to schizophrenia. In a narrative that sweeps from the first years of the century to the present, Weiner makes the process of scientific discovery and understanding almost tangible on the page. Time, Love, Memory is a brilliant work of scientific reportage. PULITZER PRIZE WINNER A dramatic story of groundbreaking scientific research of Darwin's discovery of evolution that "spark[s] not just the intellect, but the imagination" ( Washington Post Book World). Admirable and much-needed.... Weiners triumph is to reveal how evolution and science work, and to let them speak clearly for themselves. The New York Times Book Review On a desert island in the heart of the Galapagos archipelago, where Darwin received his first inklings of the theory of evolution, two scientists, Peter and Rosemary Grant, have spent twenty years proving that Darwin did not know the strength of his own theory. For among the finches of Daphne Major, natural selection is neither rare nor slow: it is taking place by the hour, and we can watch. In this remarkable story, Jonathan Weiner follows these scientists as they watch Darwin's finches and come up with a new understanding of life itself. The Beak of the Finch is an elegantly written and compelling masterpiece of theory and explication in the tradition of Stephen Jay Gould. The story of Nobel Prize–winning discoveries regarding the molecular mechanisms controlling the body’s circadian rhythm. How much of our fate is decided before we are born? Which of our characteristics is inscribed in our DNA? Weiner brings us into Benzer's Fly Rooms at the California Institute of Technology, where Benzer, and his asssociates are in the process of finding answers, often astonishing ones, to these questions. Part biography, part thrilling scientific detective story, Time, Love, Memory forcefully demonstrates how Benzer's studies are changing our world view—and even our lives. Jonathan Weiner, winner of the Pulitzer Prize for The Beak of the Finch , brings his brilliant reporting skills to the story of Seymour Benzer, the Brooklyn-born maverick scientist whose study of genetics and experiments with fruit fly genes has helped revolutionize or knowledge of the connections between DNA and behavior both animal and human. "A fascinating history--. Literate and authoritative--.Marvelously exciting." -- The New York Times Book Review Jonathan Weiner, winner of the Pulitzer Prize for The Beak of the Finch , brings his brilliant reporting skills to the story of Seymour Benzer, the Brooklyn-born maverick scientist whose study of genetics and experiments with fruit fly genes has helped revolutionize or knowledge of the connections between DNA and behavior both animal and human. How much of our fate is decided before we are born? Which of our characteristics is inscribed in our DNA? Weiner brings us into Benzer's Fly Rooms at the California Institute of Technology, where Benzer, and his asssociates are in the process of finding answers, often astonishing ones, to these questions. Part biography, part thrilling scientific detective story, Time, Love, Memory forcefully demonstrates how Benzer's studies are changing our world view--and even our lives. The story of a biologist's search for the foundations of behavior. Looking over the shoulder of some of the premier scientists in the field, biologist Weiner takes us into their laboratories to show us how pieces of DNA actually shape behavior. He focuses on the work of Seymour Benzer, who, decades ago, with James Watson and Francis Crick, helped to crack the genetic code. Then, in a simple experiment using a few test tubes, a light bulb, and 100 fruit flies, Benzer invented the genetic dissection of behavior. Now we see how he and his students find and study genes that build our inner clocks, genes that shape the way we love, and genes that decide what we can (or cannot) remember. These breakthroughs help explain secrets of human behavior and may lead to advance treatments for behavioral disorders ranging from rage to autism to schizophrenia.--From publisher description. On a desert island in the heart of the Galapagos archipelago, where Darwin received his first inklings of the theory of evolution, two scientists, Peter and Rosemary Grant, have spent twenty years proving that Darwin did not know the strength of his own theory. For among the finches of Daphne Major, natural selection is neither rare nor slow: it is taking place by the hour, and we can watch. In this dramatic story of groundbreaking scientific research, Jonathan Weiner follows these scientists as they watch Darwin's finches and come up with a new understanding of life itself. The Beak of the Finch is an elegantly written and compelling masterpiece of theory and explication in the tradition of Stephen Jay Gould. With a new preface. On a desert island in the heart of the Galapagos archipelago, where Darwin received his first inklings of the theory of evolution, two scientists, Peter and Rosemary Grant, have spent twenty years proving that Darwin did not know the strength of his own theory. For among the finches of Daphne Major, natural selection is neither rare nor slow: it is taking place by the hour, and we can watch. In this dramatic story of groundbreaking scientific research, Jonathan Weiner follows these scientists as they watch Darwin's finches and come up with a new understanding of life itself.--From publisher description Pt. 1. Occam's Castle. 1. From So Simple a Beginning. 2. The White-Eyed Fly. 3. What Is Life? 4. The Finger of the Angel. 5. A New Study, and a Dark Corner Pt. 2. Konopka's Law. 6. First Light. 7. First Choice. 8. First Time. 9. First Love. 10. First Memory Pt. 3. Pickett's Charge. 11. The Drosophila Arms. 12. Cloning an Instinct. 13. Reading an Instinct. 14. Singed Wings. 15. The Lord's Masterpiece. 16. Pavlov's Hat. 17. Rough Mountain. 18. The Knot of Our Condition. 19. Pickett's Charge. Journeys inside the cutting edge of biology and genetics to reveal how DNA helps shape human behavior and explains how these discoveries may hold the key to advanced treatments for behavioral disorders Benzer's theories are finding astonishing answers to how much DNA and genetics influence behavior based on fruit fly genetic studies. Weiner explores the genius of the maverick behind the theory A portrait of scientists Peter and Rosemary Grant that describes their work recording evolution as it occurs among the species of Galapagos finches first studied by Darwin Weiner follows scientists Peter and Rosemary Grant who, for the past 20 years, have studied the continuing evolution of the beaks of finches in the Galapagos Islands SEYMOUR BENZER'S laboratory runs along two corridors of Church Hall at the California Institute of Technology in Pasadena.