Thompson & Thompson Genetics and Genomics in Medicine (Thompson and Thompson Genetics in Medicine)

First published in 1966, Thompson and Thompson Genetics and Genomics in Medicine has become an essential textbook for medical students, genetic counseling students, students in laboratory medicine, and more advanced trainees. With its focus on fundamental principles in human genetics and genomics and their application to medicine, the book has served many as a well-thumbed resource they return to over and over. Such students can continue to depend on this valuable text, joining those in newer fields of genome data analysis for all they need to know about genetics and genomics throughout their basic science training, clinical placements and beyond. Coverage includes new discoveriessuch as the functional roles of non-coding RNAs, chromatin regulation and epigeneticslatest technologies, and new diagnoses they are enabling. Under an expanded title, this ninth edition has been completely revised by a new editorial team overseeing a large cadre of contributing authors. Support groups have also assisted to update illustrations featuring beautiful images of those living with genetic conditions. Cover Any screen. Any time. Anywhere. Front Matter Copyright Chapter Contributors Case Study Contributors Preface Contents Clinical Cases Abbreviations 1. Introduction 2. Introduction to the Human Genome 3. The Human GenomeGene Structure and Function 4. Human Genetic DiversityGenomic Variation 5. Principles of Clinical Cytogenetics and Genome Analysis 6. The Chromosomal and Genomic Basis of DiseaseDisorders of the Autosomes and Sex Chromosomes 7. Patterns of Single-Gene Inheritance 8. Principles of Clinical Epigenetics 9. Complex Inheritance of Common Multifactorial Disorders 10. Population Genetics for Genomic Medicine 11. Identifying the Genetic Basis for Human Disease 12. The Molecular Basis of Genetic Disease 13. The Molecular, Biochemical, and Cellular Basis of Genetic Disease 14. The Treatment of Genetic Disease 15. Developmental Genetics and Birth Defects 16. Cancer Genetics and Genomics 17. Genetic Counseling and Risk Assessment 18. Preconception and Prenatal Screening and Diagnosis 19. Application of Genomics to Medicine and Individualized Health Care 20. Ethical and Social Issues in Genetics and Genomics Clinical Case Studies Illustrating Genetic Principles Answers to Problems Index Confidence is ClinicalKey