Therapeutic Outcome Of Endocrine Disorders: Efficacy, Innovation And Quality Of Life (serono Symposia Usa)

Changes in the allocation of healthcare resources have raised issues related to the efficacy and outcomes of medical therapy and how such factors may be measured. The questions associated with the quality of life and functional capability of patients with chronic health conditions have been of special interest. Endocrine disorders have the potential for disrupting the general health and well-being of affected individuals and their families; thus they warrant serious attention. This symposium was convened in November 1997 at Palm Beach Gardens, Florida, to bring together medical, behavioral, and social scientists. The meeting fostered the presentation and discussion of the most current clinical research on the effects of various therapies on a wide range of endocrine disorders from diabetes to adrenal insufficiency and growth hormone deficiency. The participants, all noted national and international experts in their fields, focused their attention on both the biomedical value and effectiveness of treatment, as well as on the impact such treatments have on psychological states such as mood and cognition. Many presentations specifically emphasized the quality of life (QOL) indicators that now regu­ larly appear in many research protocols and reports. The pioneering work of two clinical researchers was a major highlight of the meeting and an Award of Recognition was presented to Robert Blizzard, M. D. , and John Money, Ph. D. , for their innovative and insightful work in pediatric endocrinology and psychosexual development. Front Matter....Pages i-xvi Outcome Research in Pediatric Psychoendocrinology and Sexology....Pages 1-6 Front Matter....Pages 7-7 Growth Hormone Replacement in Adults: The First 10 Years....Pages 9-20 Quality of Life in Children and Adults with Growth Hormone Deficiency....Pages 21-29 Treatment of Childhood Growth Hormone Deficiency: Efficacy and Innovation....Pages 30-37 Quality of Life Among Adults with Childhood Onset Growth Hormone Deficiency: A Comparison with Siblings....Pages 38-52 Quality of Life in Adults with Growth Hormone Deficiency Diagnosed During Childhood....Pages 53-60 Front Matter....Pages 61-61 The Impact of Growth Hormone Therapy on Turner Syndrome....Pages 63-68 Phenotype-Karyotype Relationships in Turner Syndrome....Pages 69-82 Standards of Care Needed to Optimize Outcomes for Turner Syndrome....Pages 83-97 Front Matter....Pages 99-99 The Non-Growth Hormone-Deficient Child: Does Therapy with Growth Hormone Produce Benefit?....Pages 101-109 Impact of Short Stature on Quality of Life: Where Is the Evidence?....Pages 110-118 Mediators of Psychological Adjustment in Children and Adolescents with Short Stature....Pages 119-130 Turner Syndrome: Psychological Functioning Rated by Parents and by the Girls Themselves....Pages 131-136 Front Matter....Pages 137-137 Evaluating Quality of Life in Diabetes: Methods and Findings....Pages 139-150 Effective Utilization of Self-Monitored Blood Glucose Data: Cognitive and Behavioral Prerequisites....Pages 151-160 Influence of Type 1 Diabetes on Childhood Growth and Development....Pages 161-164 Glycosylated Hemoglobin: A Myopic View of Diabetes Care?....Pages 165-173 Front Matter....Pages 175-175 Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency (Salt-Losing Form and Simple Virilizing Form): Long-Term Results of Treatment....Pages 177-185 Psychological Outcome in Congenital Adrenal Hyperplasia....Pages 186-199 Psychosexual Quality of Life in Adult Intersexuality: The Example of Congenital Adrenal Hyperplasia (CAH)....Pages 200-208 Front Matter....Pages 175-175 Male Fertility in Congenital Adrenal Hyperplasia....Pages 209-218 Front Matter....Pages 219-219 Growth and Development of Hypothyroid Infants....Pages 221-234 Neurobehavioral Consequences of Congenital Hypothyroidism Identified by Newborn Screening....Pages 235-254 Back Matter....Pages 255-272 Therapeutic Outcome of Endocrine Disorders: Efficacy, Innovation and Quality of Life presents the proceedings of an international symposium held from November 13-16, 1997 in Palm Beach Gardens, Florida. The proceedings discuss scientific and clinical studies related to the treatment of endocrine disorders, including growth hormone deficiency, Turner Syndrome, constitutional delay of growth, treatment of diabetes, congenital adrenal hyperplasia, and congenital hypothyroidism