The Washington Manual of Cardio-Oncology - A Practical Guide for Improved Cancer Survivorship

Written by experts in cardiovascular disease, hematology, and oncology, The Washington Manual® of Cardio-Oncology: A Practical Guide for Improved Cancer Survivorship is a clinically relevant, easy-to-use primer on the detection, management, and improved cardiovascular-based patient outcomes in adults undergoing treatment for cancer or who have previously survived cancer therapy. Edited by Drs. Daniel J. Lenihan, Joshua D. Mitchell, and Kathleen W. Zhang, this concise yet comprehensive manual provides high-yield information that reflects today's advances in risk stratification, early diagnosis, and treatment of cardiovascular disease--all in an easy-access, concisely bulleted format for on-the-go reference. Discusses the multitude of complex adverse effects of chemotherapy, targeted therapy, immunotherapy, and radiation therapy to help optimize quality of life and prolong survival in this vulnerable patient population. Includes chapters on how cancer therapy affects the myocardium, valves, pericardium and cardiac electrical system including handy reference tables on typical side effects of commonly used cancer therapies. Provides practical guidance in an easy-to-follow format that covers definition, associated drugs/therapies, epidemiology, diagnosis (history, physical exam, and diagnostic testing), treatment, and outcome/prognosis. Covers the role of non-invasive imaging modalities in the diagnosis and screening for cardiovascular disease including echocardiography, MRI, and nuclear imaging. Addresses frequently encountered clinical scenarios such as preoperative or pre-high-risk treatment evaluation with up-to-date expert consensus recommendations. Details emerging treatments and optimal use of non-invasive imaging in cardiac amyloidosis. Features easy-to-use flow-charts and tables that aid in the differentiation of cardiac masses. The Washington Manual® is a registered mark belonging to Washington University in St. Louis to which international legal protection applies. The mark is used in this publication by Wolters Kluwer Health under license from Washington University. Enrich Your eBook Reading Experience Read directly on your preferred device(s),such as computer, tablet, or smartphone. Easily convert to audiobook,powering your content with natural language text-to-speech. Title Page Copyright Page Dedication Contributors Preface Foreword Contents 1 A Practical Approach to the Evaluation of a Cardio-Oncology Patient 2 Cardiac Dysfunction: Traditional Chemotherapy, Human Epidermal Growth Factor Receptor 2–Based Therapy, and Radiation 3 Cardiac Dysfunction: Small-Molecule Kinase Inhibitors, Immune-Based Therapies, and Proteasome Inhibitors 4 Valvular Heart Disease 5 Vascular Disease in Cardio-Oncology 6 Evaluation for Ischemic Heart Disease in Cardio-Oncology 7 Pericardial Diseases in Malignancy 8 Cancer-Associated Thrombosis and Embolism 9 Cardiac Masses 10 Hypertension 11 Arrhythmias 12 Intravascular Devices and Thrombotic Complications 13 Autonomic Dysfunction 14 Echo Techniques for Cardiac Safety During and After Cancer Treatment 15 Biomarkers as a Tool For Cardiac Safety 16 MRI Techniques to Monitor Cardiac Safety During and After Cancer Treatment 17 Cancer Survivorship: Adverse Outcomes and Other Long-term Cardiovascular Considerations 18 Hematopoietic Cell Transplantation 19 Drug-Drug Interactions and the importance of a PharmD 20 Permissive Cardiotoxicity 21 Multidisciplinary Approach to Cardio-Oncology and the Use of Advanced Practice Provider 22 Cardiac Amyloidosis: General Diagnostic Approach 23 Light Chain Amyloidosis: Latest Treatment Strategies 24 Cardiac Amyloidosis: Latest Treatment Strategies for Transthyretin Amyloidosis 25 Cancer Survivors and Advanced Heart Failure Therapies Index