The stress response of critical illness : metabolic and hormonal aspects

"This book demonstrates how the latest insights into the physiopathology of the stress response can be integrated into clinical practice. The topic is particularly relevant since the metabolic changes triggered by acute stress, including adaptive responses such as resistance to anabolic signals, have recently been more precisely delineated. The underlying mechanisms of these changes are also now better understood. The authors analyse how these advances could result in better management and more effective prevention of the long-term clinical consequences of the alterations occurring during the acute phase. An international panel of respected experts discusses these topics and describes the management of some common clinical conditions"- - Springer Front Matter....Pages i-viii Introduction....Pages 1-2 Front Matter....Pages 3-3 Successive Phases of the Metabolic Response to Stress....Pages 5-18 Bioenergetics of the Stress Response....Pages 19-26 Mitochondrial Adaptation and Hibernation....Pages 27-43 Anabolic Resistance....Pages 45-60 Use of Lipids as Energy Substrates....Pages 61-74 The Stress Response of Critical Illness: Metabolic and Hormonal Aspects....Pages 75-87 Stress Hyperglycemia....Pages 89-94 Protein Metabolism....Pages 95-106 Micronutrients....Pages 107-122 Front Matter....Pages 123-123 Thyroidal Changes During Critical Illness....Pages 125-136 Stress Response: Adrenal Function....Pages 137-152 Enterohormones and the Response to Critical Illness....Pages 153-168 Adipokines in Critical Illness....Pages 169-183 Front Matter....Pages 185-185 Severe Undernutrition....Pages 187-195 The Stress Response after Traumatic Brain Injury: Metabolic and Hormonal Aspects....Pages 197-206 Sepsis and Multiple Organ Failure....Pages 207-215 The Stress Response of Critical Illness: Metabolic and Hormonal Aspects, Hormonal Regulation, Particular Clinical Situations “Morbid Obesity”....Pages 217-225 Hypermetabolic Response to Burn Injury....Pages 227-245