The Separation of Enantiomers by Capillary Electrophoresis (CHROMATOGRAPHIA CE-Series, 6)

The author is a development scientist in pharmaceutical and analytical research and development at AstraZeneca in Macclesfield. He has a general interest in separation science and has been active for a number of years in the field of research into the principles and application capillary electrophoresis in pharmaceutical analysis. This book gives a comprehensive overview on the principles of physical and mathematical modelling of enantiomer separation by CE. Method development strategies are shown and cyclodextrins as a popular group of chiral selectors as well as some other selectors used as buffer additives for enantiomer separation in free solution are described. Front Matter....Pages 1-6 Enantiomers and Separation....Pages 7-14 The Principles of Separation in CE....Pages 15-23 Modelling Enantiomer Separation by CE....Pages 24-41 Method Development Strategies....Pages 42-58 The Use of Cyclodextrins as Chiral Selectors....Pages 59-77 Other Chiral Selectors....Pages 78-92 Back Matter....Pages 93-95