The Reticuloendothelial System : A Comprehensive Treatise Volume 5 Cancer

This comprehensive treatise on the reticuloendothelial system is a project jointly shared by individual members of the Reticuloendothelial (RE) Society and bio­ medical scientists in general who are interested in the intricate system of cells and molecular moieties derived from these cells which constitute the RES. It may now be more fashionable in some quarters to consider these cells as part of what is called the mononuclear phagocytic system or the lymphoreticular system. Nevertheless, because of historical developments and current interest in the subject by investigators from many diverse areas, it seems advantageous to present in one comprehensive treatise current information and knowledge con­ cerning basic aspects of the RES, such as morphology, biochemistry, phylogeny and ontogeny, physiology, and pharmacology as well as clinical areas including immunopathology, cancer, infectious diseases, allergy, and hypersensitivity. It is anticipated that by presenting information concerning these apparently heterogeneous topics under the unifying umbrella of the RES attention will be focused on the similarities as well as interactions among the cell types constitut­ ing the RES from the viewpoint of various disciplines. The treatise editors and their editorial board, consisting predominantly of the editors of individual vol­ umes, are extremely grateful for the enthusiastic cooperation and enormous task undertaken by members of the biomedical community in general and especially by members of the American as well as European and Japanese Reticuloendothe­ lial Societies. Front Matter....Pages i-xix Neoplasms of the Mononuclear Phagocyte System....Pages 1-33 Lymphatic Metastasis of Neoplasms....Pages 35-57 Control of Tumors by the RES....Pages 59-153 Activities of Macrophages Within and Peripheral to the Tumor Mass....Pages 155-176 Stimulation of the RES and Control of Cancer Metastasis....Pages 177-191 Neoplasia and Mononuclear Phagocyte Function....Pages 193-216 Suppressor Cells and Cancer: Inhibition of Immune Functions by Macrophages....Pages 217-252 Modulation of Mononuclear Phagocytes by Cancer Chemotherapeutic Agents....Pages 253-278 Natural Killer Cells and Other Effector Cells, and Their Roles in Resistance against Cancer....Pages 279-313 Immunosuppressive Factors Produced by Tumors and Their Effects on the RES....Pages 315-326 Tumorigenic Viruses Affecting the RES....Pages 327-343 Back Matter....Pages 345-356