The Porphyrin Handbook : Medical Aspects of Porphyrins

The Porphyrin Handbook, Volume 14: Medical Aspects of Porphyrins provides information pertinent to every aspect of the chemistry, synthesis, spectroscopy, and structure of phthalocyanines. This book examines the biology and medical implications of porphyrin systems. Organized into 12 chapters, this volume begins with an overview of the underlying diagnostic features, mechanisms, and available treatments of erythropoietic disorders due to defective heme biosynthesis. This text then examines the physiopathology of acute intermittent porphyria, which is transmitted as autosomal dominant disorders with incomplete penetrance. Other chapters consider the main characteristics of congenital erythropoietic porphyria, which includes an increased synthesis, accumulation, ad excretion of porphyrins. This book discusses as well the biochemistry, pathophysiology, and clinical features of variegate porphyria in the light of several essential advances in the understanding, management, and diagnosis of variegate porphyria. The final chapter deals with the legal use of herbal and complementary medicines. This book is a valuable resource for research scientists, engineers, and clinicians. Content: Volumes in This Set , Page ii Front Matter , Page iii Copyright , Page iv Preface , Page xiii , Karl M. Kadish, Kevin M. Smith, Roger Guilard Contributors to Volumes 1–20 , Pages xv-xxx Contents of Volumes 1–20 , Pages xxxi-xl 85 - Erythropoietic Disorders Involving Heme Biosynthesis , Pages 1-21 , SYLVIA S. BOTTOMLEY 86 - Acute Intermittent Porphyria: From Clinical to Molecular Aspects , Pages 23-41 , JEAN-CHARLES DEYBACH, HERVÉ PUY 87 - Congenital Erythropoietic Porphyria , Pages 43-65 , HUBERT DE VERNEUIL, CÉCILE GED, FRANÇOIS MOREAU-GAUDRY 88 - Porphyria Cutanea Tarda and Related Disorders , Pages 67-92 , G.H. ELDER 89 - Variegate Porphyria , Pages 93-120 , PETER MEISSNER, RICHARD HIFT, ANNE CORRIGALL 90 - Protoporphyria , Pages 121-149 , TIMOTHY M. COX 91 - Miscellaneous Abnormalities in Porphyrin Production and Disposal , Pages 151-167 , RICHARD HIFT, PETER MEISSNER 92 - Porphyria Caused by Chlorinated AH Receptor Ligands and Associated Mechanisms of Liver Injury and Cancer , Pages 169-210 , ANDREW G. SMITH 93 - Porphyria: A Diagnostic Approach , Pages 211-245 , FELIX W.M. DE ROOIJ, ANNIE EDIXHOVEN, J.H.P. WILSON 94 - Approaches to Treatment and Prevention of Human Porphyrias , Pages 247-284 , KARL E. ANDERSON 95 - Management and Treatment of the Porphyrias , Pages 285-302 , J.H.P. WILSON, FELIX W.M. DE ROOIJ 96 - Porphyria: A Toxicogenetic Disease , Pages 303-338 , RICHARD J. HIFT, PETER N. MEISSNER, MICHAEL R. MOORE Index to Volume 14 , Pages 339-347 v. 1. Synthesis and organic chemistry v. 2. Heteroporphyrins, expanded porphyrins and related macrocycles v. 3. Inorganic, organometallic and coordination chemistry v. 4. Biochemistry and binding : activation of small molecules v. 5. NMR and EPR v. 6. Applications : past, present, and future v. 7. Theoretical and physical characterization v. 8. Electron transfer v. 9. Database of redox potentials and binding constants v. 10. Database of tetrapyrrole crystal structure determination v. 11. Bioinorganic and bioorganic chemistry v. 12. The iron and cobalt pigments : biosynthesis, structure, and degradation v. 13. Chlorophylls and bilins : biosynthesis, synthesis, and degradation v. 14. Medical aspects of porphyrins v. 15. Phthalocyanines : synthesis v. 16. Phthalocyanines : spectroscopic and electrochemical characterization v. 17. Phthalocyanines : properties and materials v. 18. Multiporphyrins, multiphthalocyanines, and arrays v. 19. Applications of phthalocyanines v. 20. Phthalocyanines : structural characterization. V. 11. Bioinorganic And Bioorganic Chemistry -- V. 12. The Iron And Cobalt Pigments: Biosynthesis, Structure, And Degradation -- V. 13. Chlorophylls And Bilins: Biosynthesis, Synthesis, And Degradation -- V. 14. Medical Aspects Of Porphyrins -- V. 15. Phthalocyanines: Synthesis -- V. 16. Phthalocyanines: Spectroscopic And Electrochemical Characterization -- V. 17. Phthalocyanines: Properties And Materials -- V. 18. Multiporphyrins, Multiphthalocyanines, And Arrays -- V. 19. Applications Of Phthalocyanines -- V. 20. Phthalocyanines: Structural Characterization. Editors, Karl M. Kadish, Kevin M. Smith, Roger Guilard. Includes Bibliographical References And Indexes.