داروشناسی نورزایی و تقویت نورونی، جلد 77 (مرور بین‌المللی نوروبیولوژی)

Currently, few drugs are available for the effective treatment of neurodegenerative diseases and neurodevelopmental disorders. Recent advances in neuroscience research offer hope that future strategies for treating these brain disorders will include neurogenesis and neuroenhancement as therapeutic endpoints. This volume reviews cutting-edge findings related to the pharmacological aspects of neurogenesis and neuroprotection. A broad range of topics are covered from basic lab bench research to drug discovery efforts and important clinical issues. This collection of reviews is a perfect way to become acquainted with these exciting new fields in the space of a single volume. Chapters are written with a general audience in mind, but with enough high-level discussion to appeal to specialists and experts as well. The authors have done an excellent job of challenging current paradigms and pushing the boundaries of exploration in keeping with the pioneering spirit that gave rise to these emerging areas of research. Consequently, this will be an indispensable resource for many years to come. * Provides state-of-the-art reviews spanning significant emerging fields* Discusses future directions and questions for future studies* Includes informative illustrations* Content: Regenerating the Brain Review Article Pages 1-29 David A. Greenberg, Kunlin Jin Serotonin and Brain: Evolution, Neuroplasticity, and Homeostasis Review Article Pages 31-56 Efrain C. Azmitia Therapeutic Approaches to Promoting Axonal Regeneration in the Adult Mammalian Spinal Cord Review Article Pages 57-105 Sari S. Hannila, Mustafa M. Siddiq, Marie T. Filbin Evidence for Neuroprotective Effects of Antipsychotic Drugs: Implications for the Pathophysiology and Treatment of Schizophrenia Review Article Pages 107-142 Xin‐Min Li, Haiyun Xu Neurogenesis and Neuroenhancement in the Pathophysiology and Treatment of Bipolar Disorder Review Article Pages 143-178 Robert J. Schloesser, Guang Chen, Husseini K. Manji Neuroreplacement, Growth Factor, and Small Molecule Neurotrophic Approaches for Treating Parkinson's Disease Review Article Pages 179-217 Michael J. O'Neill, Marcus J. Messenger, Viktor Lakics, Tracey K. Murray, Eric H. Karran, Philip G. Szekeres, Eric S. Nisenbaum, Kalpana M. Merchant Using Caenorhabditis elegans Models of Neurodegenerative Disease to Identify Neuroprotective Strategies Review Article Pages 219-246 Brian Kraemer, Gerard D. Schellenberg* Neuroprotection and Enhancement of Neurite Outgrowth With Small Molecular Weight Compounds From Screens of Chemical Libraries Review Article Pages 247-289 Donard S. Dwyer, Addie Dickson Series Editors Page II Contents Pages V-VII Contributors to Volume 77 Pages IX-X Preface Pages XI-XII Index Pages 291-309 Contents of Recent Volumes Pages 311-331 Currently, few drugs are available for the effective treatment of neurodegenerative diseases and neurodevelopmental disorders. Recent advances in neuroscience research offer hope that future strategies for treating these brain disorders will include neurogenesis and neuroenhancement as therapeutic endpoints. This volume reviews cutting-edge findings related to the pharmacological aspects of neurogenesis and neuroprotection. A broad range of topics are covered from basic lab bench research to drug discovery efforts and important clinical issues. This collection of reviews is a perfect way to become acquainted with these exciting new fields in the space of a single volume. Chapters are written with a general audience in mind, but with enough high-level discussion to appeal to specialists and experts as well. The authors have done an excellent job of challenging current paradigms and pushing the boundaries of exploration in keeping with the pioneering spirit that gave rise to these emerging areas of research. Consequently, this will be an indispensable resource for many years to come.

* Provides state-of-the-art reviews spanning significant emerging fields
* Discusses future directions and questions for future studies
* Includes informative illustrations
* Currently, few drugs are available for the effective treatment of neurodegenerative diseases and neurodevelopmental disorders. Recent advances in neuroscience research offer hope that future strategies for treating these brain disorders will include neurogenesis and neuroenhancement as therapeutic endpoints. This volume reviews cutting-edge findings related to the pharmacological aspects of neurogenesis and neuroprotection. A broad range of topics are covered from basic lab bench research to drug discovery efforts and important clinical issues. This collection of reviews is a perfect way to become acquainted with these exciting new fields in the space of a single volume. Chapters are written with a general audience in mind, but with enough high-level discussion to appeal to specialists and experts as well. The authors have done an excellent job of challenging current paradigms and pushing the boundaries of exploration in keeping with the pioneering spirit that gave rise to these emerging areas of research. Consequently, this will be an indispensable resource for many years to come. * Provides state-of-the-art reviews spanning significant emerging fields * Discusses future directions and questions for future studies * Includes informative illustrations * The volume in the International Review of Neurobiology series summarizes recent developments concerning the use of drugs to promote neurogenesis in the brain and to produce neuroenhancement a new term that encompasses neuroprotection and optimization of neuronal function