The Microflow Cytometer

This book describes the continuing development of inexpensive, portable flow cytometers through incorporation of microfluidic technologies and small optical components. The underlying microfluidic theories essential for microflow cytometry isdiscussed in detail, as well as advances that are representative of the current state-of-the-art. Design and fabrication strategies for these innovative component technologies will be subsequently presented by numerous research groups leading the field. Integration of the components into functional prototype devices for analysis and manipulation of particles and cells are reviewed. Multiple currently available commercial systems are examined to highlight both strengths and areas for improvement. Flow cytometry has proven to be an invaluable tool for both analysis of cellular populations and detection of biomarkers. Utility of flow cytometry will not be limited to the laboratory for much longer. This volume describes the continuing development of inexpensive, portable flow cytometers through incorporation of microscale technologies and small optical components. The underlying microfluidic theories essential for microflow cytometry are discussed, as well as advances that are representative of the current state-of-the-art. Leading researchers describe the design and fabrication strategies for innovative component technologies. Integration of the components into functional prototype devices is reviewed with a goal of on-site analysis and manipulation of particles and cells. Multiple currently available commercial systems are examined to highlight both strengths and areas for necessary improvement. --Book Jacket "The field of microfluidic flow cytometry is developing at a fast rate. New micro devices are being developed that are cheap, easy to use and tailored to specific applications. This book brings together a compilation of the state of the art in the field. The authors offer an in-depth insight into technology issues and future perspectives. An excellent reference for scientists and technologist developing these micro-systems and for all interested in the future of microflow cytometry."--Hywel Morgan University of Southampton, UK "Great book! Excellent compilation. From history of the very early days of flow cytometers to the latest unique unconventional microflow cytometers. From commercialization philosophy to cutting edge engineering designs. From fluid mechanics to optics to electronic circuit considerations. Well balanced and comprehensive."--Shuichi Takayama University of Michigan, USA. Read more... Abstract: Describes the development of inexpensive, portable flow cytometers through incorporation of microfluidic technologies and small optical components. This work reviews integration of the components into functional prototype devices for analysis and manipulation of particles and cells The field of microfluidic flow cytometry is growing at a fast rate. This volume describes the development of inexpensive, portable flow cytometers through incorporation of microfluidic technologies and small optical components.