The Male Factor in Human Infertility Diagnosis and Treatment : Themes from the Xlth World Congress on Fertility and Sterility, Dublin, June 1983, held under the Auspices of the International Federation of Fertility Societies

This book is a compilation of edited papers which were presented at the XIth World Congress of Fertility and Sterility held in June 1983 in Dublin, Ireland. Although it has long been known that male factors are responsible in at least 30% of infertile couples only recently have concerted efforts been made on the part of urologists, gynaecologists and basic scientists to identify these factors more precisely. The nature of spermatogenesis is complex but application of various scientific methods have at last opened up new and promising approaches to our understanding of this subject. Clinical results however have been depressing; the majority of treatments lack realistic evaluation and are initiated in hope rather than with a sound scientific basis. We anticipate that this volume will in some small way correct these deficiencies. The papers have been grouped into related topics. The first section deals with the evaluation of the spermatozoa and includes a critical assessment of the recently introduced zona-free hamster egg test of sperm function. Further sections include the biochemistry of gonadal function and the immunology of male reproduction; most papers are concerned with studies in the human. The clinical sections cover medical and surgical approaches to treatment and the final section deals with various aspects of AID practice. Front Matter....Pages i-xxii Front Matter....Pages 1-1 A computerized technique for the measurement of sperm cell velocity: correlation of the results with in vitro fertilization assays....Pages 3-7 Automatic analysis of sperm characteristics by means of a microcomputer system....Pages 9-12 In vitro cross penetration testing in infertile couples....Pages 13-16 A new standardized in vitro penetration test (bovine) measuring the capacity of fertilization. I....Pages 17-21 A new standardized in vitro penetration test (bovine) measuring the capacity of fertilization. II....Pages 23-26 Penetration of zona-free hamster eggs by human spermatozoa. Comparison of two methods....Pages 27-32 Reduced penetration of zona-free hamster ova by cryopreserved human spermatozoa....Pages 33-36 Effect of caffeine on human sperm penetration into zona-free hamster ova....Pages 37-40 The variability and clinical value of a heterologous ovum penetration test....Pages 41-45 Laser-induced stimulation of sperm motility in vitro ....Pages 47-49 Time-sequential observation on human sperm penetration into zona pellucida-free hamster oocytes by scanning electron microscopy....Pages 51-56 Analysis of various experimental conditions on the rate of human sperm penetration into zona-free hamster ova....Pages 57-60 Front Matter....Pages 61-61 Levels of vitamin B 12 and folic acid in seminal plasma from subjects with normal semen analysis and patients with idiopathic oligoasthenozoospermia....Pages 63-67 Functional role of relaxin in the human seminal fluid....Pages 69-72 Hyperprolactinaemia and abnormal seminal cytology....Pages 73-77 Serum FSH and spermatogenesis....Pages 79-84 Response to FSH of human Sertoli cells in culture....Pages 85-89 Anaerobic urinary and prostatic bacteria, and prostatic biochemical markers in urine after prostatic massage of infertile men....Pages 91-93 Effects of bombesin on the pituitary response to TRH and LHRH in humans....Pages 95-98 Front Matter....Pages 99-99 Characteristics of a monoclonal anti-human sperm antibody....Pages 101-104 Front Matter....Pages 99-99 Topographical analysis of the surface of human spermatozoa by means of monoclonal antibodies....Pages 105-109 Human seminal plasma proteins: identification and preliminary characterization of a human sperm coating antigen (h-SCA) protein in physiological and pathological conditions....Pages 111-115 Antigenicity of sperm cells after freezing and thawing....Pages 117-121 A radioimmunoassay for antisperm antibodies using 125 I-labelled protein A....Pages 123-126 Human cervical response to artificial insemination....Pages 127-131 Front Matter....Pages 133-133 Kallman’s syndrome — sustained spermatogenesis three years after cessation of treatment....Pages 135-138 Effects of testosterone undecanoate on semen quality and sexual behaviour....Pages 139-141 Tamoxifen in the treatment of reduced semen quality: Preliminary results....Pages 143-146 Tamoxifen in the management of male subfertility — a retrospective analysis....Pages 147-150 Increased sperm count in 41 cases of idiopathic normogonadotropic oligozoospermia following treatment with tamoxifen....Pages 151-154 Treatment of oligozoospermia with Chinese herb medicine (Hachimi-Jiou-Gan)....Pages 155-159 Bacterial contamination of semen of infertile couples and the effect of antibiotic treatment of semen quality and fertility....Pages 161-166 Front Matter....Pages 167-167 Effects on semen parameters and pregnancy rate after occlusion of the spermatic vein in subfertile men with idiopathic varicocele....Pages 169-174 Varicocelectomy for oligozoospermia....Pages 175-179 Emission failure due to retroperitoneal lymphadenectomy: first report of a pregnancy after insemination of spermatozoa obtained by midodrin-induced retrograde ejaculation....Pages 181-185 Restoration of antegrade ejaculation following radical retroperitoneal lymphadenectomy....Pages 187-189 Transurethral resection of verumontanum for ejaculatory duct stenosis and oligozoospermia....Pages 191-196 Results of microsurgical testicular autotransplantation in nine patients with high-lying undescended testes....Pages 197-201 Front Matter....Pages 203-203 Echosonographic control of follicular growth in heterologous therapeutic insemination (AID)....Pages 205-208 A comparison of fresh and frozen semen in AID practice....Pages 209-216 Front Matter....Pages 203-203 AID in the problem patient....Pages 217-221 Repeat pregnancies with AID....Pages 223-226 The post-insemination test in predicting the outcome of artificial insemination with husband’s semen....Pages 227-232 The relationship between the survival of human spermatozoa in culture medium and pregnancy rate....Pages 233-236 Duration of vitality and migrating ability of +4 °C cryopreserved human spermatozoa....Pages 237-241 Male sterility caused by anejaculation — aetiology, diagnosis and treatment....Pages 243-246 Psychological patterns of AID-demanding marital couples....Pages 247-255 The complexity of psychological issues involved in artificial insemination by donor....Pages 257-260 Secrecy in the provision of artificial insemination by donor (AID)....Pages 261-264 Relationships between results of post-coital test and parameters of semen analysis....Pages 265-269 Seminal plasma isoenzyme LDH-X values in extreme oligozoospermia....Pages 271-274 Back Matter....Pages 275-279