The Make Up: A Sweet Romantic Comedy (Falling for Franklin Series Book 2)

Andrews’ remains as it was from the beginning: an authored textwhose one volume is filled with clinical signs, symptoms, diagnostictests, and therapeutic pearls. The authors are committed to keepingAndrews’ as an excellent tool for anyone who needs help in diagnosinga patient with a clinical conundrum or treating a patient witha therapeutically challenging disease.Andrews’ is primarily intended for the practicing dermatologist.It is meant to be used on the desktop of his or her clinic, givingconsistent, concise advice on the whole spectrum of clinical situationsfaced in the course of a busy workday.Many major changes have been made to this edition.We selectively discarded older concepts. By eliminatingolder, not currently useful information we maintain the briefbut complete one-volume presentation that we and all previousauthors have emphasized. Additionally, older references have beenupdated. The classic early works are not cited; instead we havechosen to include only new citations and let the bibliographiesof the current work provide the older references as you needthem. A major effort in this edition was to reillustrate the textwith hundreds of new color images. Many have been added to theprinted text; you will also find a number only in the online version.Enjoy! We have looked to our own collections to accomplish this.Two years ago we published an Atlas to accompany this textbook.Many newer photos in our text are included in the Atlas. TheAtlas has over 3000 images covering the depth and breadth ofour specialty and is a superb companion to this textbook. Front Cover......Page 1 IFC-Expert Consult PIN Page......Page 2 Andrews' Diseases of the Skin......Page 3 Copyright Page......Page 6 Z......Page 0 Video Contents......Page 7 Preface and Acknowledgments to the Thirteenth Edition......Page 8 Dedication......Page 10 The Authors......Page 11 Keratinocytes......Page 12 Langerhans Cells......Page 14 Eccrine Sweat Units......Page 15 Hair Follicles......Page 16 Nails......Page 18 Vasculature......Page 19 Subcutaneous Tissue (Fat)......Page 20 Vesicles (Blisters)......Page 23 Bullae......Page 24 Scars......Page 25 Evolution......Page 26 Color......Page 27 Self-Examination......Page 28 Electrical Burns......Page 32 Miliaria Crystallina......Page 33 Erythema Ab Igne......Page 34 Acrocyanosis......Page 35 Frostbite......Page 36 Warm Water Immersion Foot......Page 37 Treatment......Page 38 Ephelis (Freckle) and Lentigo......Page 39 Photoaging (Dermatoheliosis)......Page 40 Colloid Milium......Page 41 Phototoxic Reactions......Page 42 Phytophotodermatitis.......Page 43 Polymorphous Light Eruption......Page 44 Brachioradial Pruritus......Page 46 Solar Urticaria......Page 47 Chronic Actinic Dermatitis......Page 48 Acute Radiodermatitis......Page 49 Radiation Cancer......Page 50 Callus......Page 51 Pressure Ulcers (Decubitus)......Page 52 Subcutaneous Emphysema......Page 53 Narcotic Dermopathy......Page 54 Tattoo......Page 55 Zirconium Granuloma......Page 56 Carbon Stain......Page 57 Injected Filler Substances......Page 58 Treatment......Page 63 Chronic Kidney Disease......Page 64 Primary Biliary Cirrhosis.......Page 65 Pruritus Ani......Page 66 Pruritus Scroti......Page 67 Aquagenic Pruritus and Aquadynia......Page 68 Prurigo Pigmentosa......Page 69 Treatment.......Page 70 Psychodermatology......Page 71 Delusional Infestation (Delusions of Parasitosis)......Page 72 Excoriation Disorder......Page 73 Trichotillomania......Page 74 Scalp Dysesthesia......Page 75 Notalgia Paresthetica......Page 76 Complex Regional Pain Syndrome......Page 77 Sciatic Nerve Injury......Page 78 Hereditary Sensory and Autonomic Neuropathies......Page 79 Epidemiology......Page 82 Food Allergy......Page 83 Clinical Manifestations......Page 84 Atopic Dermatitis in Adolescents and Adults......Page 85 Cutaneous Stigmata......Page 86 Susceptibility to Infection......Page 87 Barrier Repair......Page 88 Topical Calcineurin Inhibitors......Page 89 Other Immunosuppressive Agents......Page 90 Management of Acute Flare......Page 91 Breast Eczema (Nipple Eczema)......Page 92 Hand Eczema......Page 93 Pulpitis (Fingertip Hand Dermatitis).......Page 94 Diaper (Napkin) Dermatitis......Page 95 Juvenile Plantar Dermatosis......Page 96 Nummular Eczema (Discoid Eczema)......Page 97 Hormone-Induced Dermatoses......Page 98 X-Linked Agammaglobulinemia......Page 99 Common Variable Immunodeficiency......Page 100 IPEX Syndrome......Page 101 Miscellaneous Genetic Disorders of Cellular Immunity......Page 102 Ataxia Telangiectasia......Page 103 GATA2 Deficiency (WILD Syndrome)......Page 104 Chronic Granulomatous Disease......Page 105 Hyperimmunoglobulinemia E Syndrome......Page 106 Complement Deficiency......Page 107 Graft-Versus-Host Disease......Page 108 Graft-Versus-Host Disease in Solid-Organ Transplantation......Page 109 Acids......Page 113 Tear Gas Dermatitis......Page 114 Hydrocarbons......Page 115 Allergic Contact Dermatitis......Page 116 Head and Neck.......Page 117 Dermatitis Resulting From Plants......Page 118 Toxicodendron (Poison Ivy).......Page 119 Tree-Associated Plants.......Page 120 Plant Derivatives.......Page 121 Dermatitis From Clothing......Page 122 Nickel.......Page 123 Cobalt.......Page 124 Rubber Dermatitis......Page 125 Epoxy Resins.......Page 126 Fragrances.......Page 127 Bleaching Creams.......Page 128 Preservatives......Page 129 Topical Drug Contact Dermatitis......Page 130 Corticosteroids.......Page 131 Nonimmunologic Mechanism.......Page 132 Epidemiology......Page 133 Pathogenesis......Page 134 Exanthems (Morbilliform or Maculopapular Reactions)......Page 135 Drug-Induced Hypersensitivity Syndrome or Drug Reaction With Eosinophilia and Systemic Symptoms......Page 136 Minocycline Hypersensitivity Syndrome......Page 137 Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis......Page 138 Human Immunodeficiency Virus Disease and Drug Reactions......Page 140 Fixed Drug Reactions (Eruptions)......Page 141 Acute Generalized Exanthematous Pustulosis......Page 142 Urticaria/Angioedema......Page 143 Photosensitivity Reactions (Photosensitive Drug Reactions)......Page 144 Anticoagulant-Induced Skin Necrosis......Page 146 Vitamin K Reactions......Page 147 Drug-Induced Pigmentation......Page 148 Adverse Reactions to Chemotherapeutic Agents......Page 150 Chemotherapy-Induced Dyspigmentation......Page 151 Palifermin-Associated Papular Eruption......Page 152 BRAF-Inhibitor Reactions......Page 153 Radiation Enhancement and Recall Reactions......Page 154 Tumor Necrosis Factor Inhibitors......Page 155 JAK Inhibitors......Page 156 Iododerma......Page 157 Topical Application......Page 158 Systemic Corticosteroids......Page 159 Erythema Toxicum Neonatorum......Page 164 Clinical Features......Page 165 Differential Diagnosis......Page 166 Erythema Annulare Centrifugum......Page 167 Eosinophilic Cellulitis (Wells Syndrome)......Page 168 Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)......Page 169 Pyoderma Gangrenosum......Page 171 Autoinflammatory Syndromes......Page 173 Urticaria (Hives)......Page 174 Cholinergic Urticaria.......Page 175 Pressure Urticaria (Delayed Pressure Urticaria).......Page 176 Clinical Evaluation......Page 177 Angioedema......Page 178 Acquired C1 Esterase Inhibitor Deficiency......Page 179 Anaphylaxis......Page 180 Differential Diagnosis.......Page 184 Tumid Lupus Erythematosus......Page 186 Subacute Cutaneous Lupus Erythematosus......Page 187 Systemic Lupus Erythematosus......Page 188 Cutaneous Manifestations......Page 189 Systemic Manifestations......Page 190 Immunologic Findings......Page 191 Antimalarials.......Page 192 Other Therapy.......Page 193 Skin Findings......Page 194 Diagnostic Criteria......Page 195 Etiology......Page 196 Treatment......Page 197 Localized Morphea......Page 198 Atrophoderma of Pasini and Pierini......Page 199 Progressive Systemic Sclerosis......Page 200 Laboratory Findings.......Page 201 Pathogenesis......Page 202 Treatment......Page 203 Eosinophilic Fasciitis......Page 204 Nephrogenic Systemic Fibrosis......Page 205 Sjögren Syndrome (Sicca Syndrome)......Page 206 Rheumatoid Neutrophilic Dermatosis......Page 207 Juvenile Rheumatoid Arthritis (Juvenile Idiopathic Arthritis)......Page 208 Relapsing Polychondritis......Page 209 Generalized Lichen Myxedematosus......Page 219 Discrete Papular Lichen Myxedematosus......Page 220 Atypical or Intermediate Lichen Myxedematosus......Page 221 Scleredema......Page 222 Follicular Mucinosis (Alopecia Mucinosa)......Page 223 Myxoid Cysts......Page 224 Chapter References......Page 225 Differential Diagnosis......Page 228 Clinical Features......Page 229 Seborrheic-Like Psoriasis......Page 230 Generalized Pustular Psoriasis (von Zumbusch Psoriasis)......Page 231 Course......Page 232 Streptococci......Page 233 Corticosteroids.......Page 234 Hyperthermia......Page 235 Biologic Agents......Page 236 Evolving Therapies......Page 237 Clinical Features......Page 238 Dermatitis Repens......Page 239 Infantile Acropustulosis......Page 240 Treatment......Page 245 Clinical Features......Page 246 Histology......Page 247 Small Plaque Parapsoriasis......Page 248 Keratosis Punctata of the Palmar Creases......Page 249 Acrokeratoelastoidosis......Page 250 Mutilating Keratoderma of Vohwinkel......Page 251 Keratolysis Exfoliativa (Lamellar Dyshidrosis, Recurrent Palmar Peeling)......Page 252 Etiology......Page 253 Treatment......Page 254 Lichen Planus......Page 257 Erosive/Ulcerative/Mucosal Lichen Planus......Page 259 Bullous Lichen Planus......Page 260 Pathogenesis and Histology......Page 261 Treatment......Page 262 Adnexal Lichen Planus: Follicular Lichen Planus (Lichen Planopilaris) and Acrosyringeal Lichen Planus......Page 264 Lichen Planus Pigmentosus/Actinicus......Page 265 Keratosis Lichenoides Chronica......Page 266 Clinical Features......Page 267 Lichen Striatus......Page 268 Lichen Sclerosus (Lichen Sclerosus Et Atrophicus)......Page 269 Treatment......Page 271 Pathogenesis......Page 277 General Principles......Page 279 Topical Antibacterials.......Page 280 Bacterial Resistance.......Page 281 Isotretinoin.......Page 282 Intralesional Corticosteroids.......Page 283 Complications......Page 284 Acne Conglobata......Page 285 Excoriated Acne......Page 286 Gram-Negative Folliculitis......Page 287 Clinical Features......Page 288 Treatment......Page 289 Dissecting Cellulitis of the Scalp......Page 290 Clinical Features......Page 291 Ocular Findings......Page 292 Oral Therapy......Page 293 Other Considerations......Page 294 Perioral Dermatitis......Page 295 Granulomatous Perioral Dermatitis in Children......Page 296 Impetigo......Page 299 Folliculitis......Page 301 Furunculosis......Page 302 Botryomycosis......Page 303 Gram-Positive Toxic Shock Syndromes......Page 304 Scarlet Fever......Page 306 Erysipelas......Page 307 Necrotizing Fasciitis......Page 308 Streptococcal Intertrigo......Page 309 Streptococcus iniae Infections......Page 310 Anthrax......Page 311 Cutaneous Diphtheria......Page 312 Intertrigo......Page 313 Gas Gangrene (Clostridial Myonecrosis)......Page 314 Actinomycosis......Page 315 Ecthyma Gangrenosum......Page 316 Pseudomonas aeruginosa Folliculitis (Hot Tub Folliculitis)......Page 317 Gram-Negative Folliculitis......Page 318 Chancroid......Page 319 Granuloma Inguinale (Granuloma Venereum, Donovanosis)......Page 320 Gonococcemia......Page 321 Vibrio Vulnificus Infection......Page 322 Shigellosis......Page 323 Pasteurellosis......Page 324 Glanders......Page 325 Cat-Scratch Disease......Page 326 Treatment......Page 327 Rat-Bite Fever......Page 328 Tularemia......Page 329 Epidemic Typhus......Page 330 Rocky Mountain Spotted Fever......Page 331 Ehrlichiosis......Page 332 Lyme Disease......Page 333 Mycoplasma......Page 335 Lymphogranuloma Venereum......Page 336 Treatment......Page 337 Antifungal Therapy......Page 342 Tinea Capitis......Page 343 Differential Diagnosis......Page 344 Tinea Barbae......Page 345 Tinea Corporis (Tinea Circinata)......Page 346 Tinea Imbricata (Tokelau)......Page 347 Tinea of Hands and Feet......Page 348 Treatment......Page 349 Onychomycosis (Tinea Unguium)......Page 350 Treatment......Page 351 Topical Anticandidal Agents......Page 352 Oral Candidiasis (Thrush)......Page 353 Erosio Interdigitalis Blastomycetica......Page 354 Chronic Mucocutaneous Candidiasis......Page 355 Geotrichosis......Page 356 Tinea Versicolor (Pityriasis Versicolor)......Page 357 The Deep Mycoses......Page 358 Culture......Page 359 Progressive Disseminated Histoplasmosis......Page 360 Epidemiology......Page 361 Cryptococcosis......Page 362 Etiology and Pathology......Page 363 South American Blastomycosis......Page 364 Etiology and Pathology......Page 365 Treatment......Page 366 Treatment......Page 367 Treatment......Page 368 Diagnosis......Page 369 Rhinosporidiosis......Page 370 Diagnosis......Page 371 Fusariosis......Page 372 Disease Caused by Algae (Protothecosis)......Page 373 Epidemiology......Page 380 Primary Inoculation Tuberculosis (Primary Tuberculous Complex, Tuberculous Chancre)......Page 381 Lupus Vulgaris.......Page 382 Cutaneous Tuberculosis From Endogenous Source by Direct Extension (Scrofuloderma and Periorificial Tuberculosis)......Page 383 Sporotrichoid Tuberculosis......Page 384 Papulonecrotic Tuberculid......Page 385 Diagnosis of Cutaneous Tuberculosis......Page 386 Treatment......Page 387 Fish Tank Granuloma......Page 388 Rapidly Growing Mycobacteria......Page 389 Mycobacterium Kansasii......Page 390 Diagnosis......Page 394 Early and Indeterminate Hansen Disease......Page 395 Borderline Lepromatous (BL) Leprosy......Page 396 Nerve Involvement......Page 397 Organ Transplantation......Page 399 Type 1 Reactions (Reversal, Lepra, and Downgrading Reactions)......Page 400 Treatment......Page 401 Prevention......Page 403 Syphilis......Page 406 Chancre (Primary Stage)......Page 407 Papular Eruptions.......Page 409 Histopathology......Page 411 Tertiary Cutaneous Syphilis......Page 412 Late (Parenchymatous) Neurosyphilis.......Page 413 Early Congenital Syphilis......Page 414 Diagnosis......Page 415 Serologic Testing After Treatment......Page 416 Syphilis and HIV Disease......Page 417 Late Yaws......Page 418 Histopathology......Page 419 Treatment......Page 420 Herpes Simplex Virus (Human Herpesvirus Types 1 and 2)......Page 424 Orolabial Herpes......Page 425 Herpetic Whitlow......Page 426 Genital Herpes......Page 427 Intrauterine and Neonatal Herpes Simplex......Page 428 Eczema Herpeticum (Kaposi Varicelliform Eruption)......Page 429 Immunocompromised Patients......Page 430 Differential Diagnosis......Page 431 Varicella......Page 432 Treatment......Page 433 Immunocompromised Patients......Page 434 Disseminated Herpes Zoster......Page 436 Treatment......Page 437 Zoster-Associated Pain (Postherpetic Neuralgia)......Page 438 Diagnosis......Page 439 Inflammatory Skin Lesions after Zoster Infection (Isotopic Response)......Page 440 Epstein-Barr Virus (Human Herpesvirus Type 4)......Page 441 Cytomegalovirus (Cytomegalic Inclusion Disease); Human Herpesvirus Type 5......Page 443 Human Herpesvirus 8......Page 444 Hepatitis B Virus......Page 445 Hepatitis C Virus......Page 446 Gianotti-Crosti Syndrome (Papular Acrodermatitis of Childhood, Papulovesicular Acrolocated Syndrome)......Page 447 Variola Major (Smallpox)......Page 448 Generalized Vaccinia......Page 449 Other Skin Lesions at Vaccination Scars.......Page 450 Orf.......Page 451 Molluscum Contagiosum......Page 452 Enterovirus Infections......Page 455 Hand-Foot-and-Mouth Disease......Page 456 Measles......Page 457 Parvovirus Group......Page 459 Papular-Purpuric Gloves-and-Socks Syndrome......Page 460 West Nile Fever......Page 461 Dengue......Page 462 Zika Virus......Page 463 Warts (Verruca)......Page 464 Flat Warts (Verruca Plana)......Page 465 Histologic Features......Page 466 Destructive/Occlusive Therapy.......Page 467 Genital Warts (External Genital Warts).......Page 468 Condylomata Acuminata.......Page 469 Diagnosis of Genital Warts.......Page 470 Treatment.......Page 471 Recurrent Respiratory (Laryngeal) Papillomatosis......Page 472 Epidermodysplasia Verruciformis......Page 473 Immunosuppressed Patients......Page 474 Human T-Lymphotropic Virus 1......Page 476 Human Immunodeficiency Virus......Page 477 HIV-Associated Pruritus......Page 478 HIV-Associated Neoplasia......Page 479 AIDS and Kaposi Sarcoma......Page 480 Trichomoniasis......Page 491 Clinical Features.......Page 492 Epidemiology.......Page 493 Clinical Features.......Page 494 Clinical Features.......Page 495 Human Trypanosomiasis......Page 496 Toxoplasmosis......Page 497 Hydroid, Sea Anemone, and Coral Dermatitis......Page 498 Dogger Bank Itch......Page 499 Visceral Schistosomiasis (Bilharziasis)......Page 500 Enterobiasis (Pinworm Infection, Seatworm Infection, Oxyuriasis)......Page 501 Creeping Eruption (Larva Migrans)......Page 502 Dracunculiasis (Guinea Worm Disease, Dracontiasis, Medina Worm)......Page 503 Elephantiasis Tropica (Elephantiasis Arabum)......Page 504 Onchocerciasis......Page 505 Trichinosis......Page 506 Prevention of Arthropod-Related Disease......Page 507 Centipede Bites (Chilopoda)......Page 508 Moth Dermatitis......Page 509 Reduviid Bites......Page 510 Pediculosis Capitis.......Page 511 Mosquito Bites......Page 512 Blister Beetle Dermatitis......Page 513 Ants......Page 514 Tungiasis......Page 515 Tick Paralysis......Page 516 Scabies.......Page 517 Animal Scabies.......Page 518 Other Mite-Related Dermatitides.......Page 519 Latrodectism......Page 520 Stingray Injury......Page 521 Lizard Bite......Page 522 Etiologic Factors......Page 526 Systemic Therapy......Page 528 Pemphigus Vegetans......Page 529 Pemphigus Foliaceus......Page 530 Endemic Pemphigus (Fogo Selvagem)......Page 531 Paraneoplastic Pemphigus......Page 532 IgA Pemphigus (Intraepidermal Neutrophilic IgA Dermatosis)......Page 533 Clinical Features......Page 534 Treatment......Page 535 Course and Prognosis......Page 536 Pathogenesis......Page 537 Papular Dermatitis of Pregnancy......Page 538 Clinical Features......Page 539 Treatment......Page 540 Epidermolysis Bullosa Acquisita......Page 541 Clinical Features......Page 542 Histopathology......Page 543 Adult Linear IgA Disease......Page 544 Childhood Linear IgA Disease (Chronic Bullous Disease of Childhood)......Page 545 Transient Acantholytic Dermatosis (Grover Disease)......Page 546 Hypovitaminosis A (Phrynoderma)......Page 552 Vitamin D......Page 553 Vitamin B2 Deficiency......Page 554 Vitamin C Deficiency (Scurvy)......Page 555 Clinical Features......Page 556 Biotin Deficiency......Page 557 Zinc Deficiency......Page 558 Essential Fatty Acid Deficiency......Page 559 Kwashiorkor......Page 560 Carotenemia and Lycopenemia......Page 561 Septal Panniculitis (Acute and Chronic Erythema Nodosum)......Page 564 Nodular Vasculitis and Erythema Induratum......Page 566 Lipodermatosclerosis......Page 567 Subcutaneous Fat Necrosis of the Newborn......Page 568 Traumatic Panniculitis......Page 569 Pancreatic Panniculitis (Subcutaneous Fat Necrosis)......Page 570 Cytophagic Histiocytic Panniculitis......Page 571 Familial Partial Lipodystrophy......Page 572 Acquired Partial Lipodystrophy (Barraquer-Simons Syndrome)......Page 573 Localized Lipodystrophy......Page 574 Cushing Syndrome......Page 577 Addison Disease......Page 578 Androgen-Dependent Syndromes......Page 579 Mild Hypothyroidism......Page 580 Hyperthyroidism......Page 581 Hypoparathyroidism......Page 582 Acanthosis Nigricans......Page 583 Acanthosis Nigricans Associated With Insulin-Resistant States and Syndromes......Page 584 Diagnosis and Treatment......Page 585 Reactive Perforating Collagenosis......Page 587 Pseudoxanthoma Elasticum......Page 589 Ehlers-Danlos Syndromes......Page 590 Loeys Dietz Syndrome......Page 592 Blepharochalasis......Page 593 Striae Distensae (Stretch Marks)......Page 594 Osteogenesis Imperfecta......Page 595 Primary Systemic Amyloidosis (AL Amyloidosis)......Page 599 Dialysis-Associated Amyloidosis (β2-Microglobulin Amyloidosis)......Page 600 Treatment......Page 601 Hereditary Cutaneous Amyloidosis Syndromes......Page 602 Familial Syndromes Associated With Amyloidosis (Heredofamilial Amyloidosis)......Page 603 Porphyria Cutanea Tarda......Page 604 Hepatoerythropoietic Porphyria......Page 606 Erythropoietic Protoporphyria......Page 607 Congenital Erythropoietic Porphyria......Page 608 Transient Erythroporphyria of Infancy (Purpuric Phototherapy-Induced Eruption)......Page 609 Metastatic Calcinosis Cutis......Page 611 Tumoral Calcinosis......Page 612 Osteoma Cutis......Page 613 Xanthoma Tuberosum......Page 614 Xanthoma Planum (Plane Xanthoma)......Page 615 Primary Hyperlipoproteinemias......Page 616 Cerebrotendinous Xanthomatosis......Page 617 Familial α-Lipoprotein Deficiency (Hypoalphalipoproteinemia, Tangier Disease)......Page 618 Gaucher Disease......Page 619 Lipoid Proteinosis......Page 620 Angiokeratoma Corporis Diffusum (Fabry Disease)......Page 621 Necrobiosis Lipoidica/Necrobiosis Lipoidica Diabeticorum......Page 622 Limited Joint Mobility and Waxy Skin......Page 623 Hartnup Disease......Page 624 Alkaptonuria and Ochronosis......Page 625 Exogenous Ochronosis......Page 626 Hunter Syndrome (Mucopolysaccharidosis II)......Page 627 CADASIL Syndrome......Page 628 Lesch-Nyhan Syndrome......Page 629 Incontinentia Pigmenti......Page 634 Naegeli-Franceschetti-Jadassohn Syndrome......Page 635 Pigmentary Mosaicism With Hyperpigmentation......Page 636 Neurofibromatosis Type 1......Page 637 Screening and Monitoring for Complications......Page 639 Costello Syndrome......Page 640 Epidermal Nevus Syndromes......Page 641 Tuberous Sclerosis......Page 642 Treatment......Page 643 Ataxia-Telangiectasia......Page 644 Skin Fragility (Plakoglobin Mutation)......Page 645 Epidermolysis Bullosa Simplex Migratory Circinate......Page 646 Dominant Dystrophic Epidermolysis Bullosa......Page 647 Kindler Syndrome (Acrokeratotic Poikiloderma, Weary-Kindler Syndrome)......Page 648 Familial Benign Chronic Pemphigus (Hailey-Hailey Disease)......Page 649 X-Linked Ichthyosis......Page 650 Harlequin Ichthyosis......Page 651 Treatment......Page 652 Chondrodysplasia Punctata......Page 653 Refsum Syndrome......Page 654 Congenital Hemidysplasia With Ichthyosiform Erythroderma and Limb Defects (CHILD) Syndrome......Page 655 Erythrokeratodermias......Page 656 Porokeratosis......Page 657 Porokeratosis Palmaris, Plantaris, et Disseminata......Page 658 Darier Disease (Keratosis Follicularis, Darier-White Disease)......Page 659 Pachyonychia Congenita......Page 660 Dyskeratosis Congenita (Zinsser-Cole-Engman Syndrome)......Page 661 EEC Syndrome......Page 662 Nectinopathies......Page 663 Aplasia Cutis Congenita......Page 664 Focal Dermal Hypoplasia (Goltz Syndrome)......Page 665 Progeria (Hutchinson-Gilford Syndrome)......Page 666 Trichothiodystrophy......Page 667 Rothmund-Thomson Syndrome (Poikiloderma Congenitale)......Page 668 Popliteal Pterygium Syndrome......Page 669 Crow-Fukase (POEMS) Syndrome......Page 670 Atrichia With Papules......Page 671 Keratosis Follicularis Spinulosa Decalvans (Siemens-1 Syndrome)......Page 672 MELAS Syndrome......Page 673 Infantile Hemangioma......Page 679 Kaposiform Hemangioendothelioma......Page 682 Kasabach-Merritt Syndrome......Page 683 Endovascular Papillary Angioendothelioma (Dabska Tumor)......Page 684 Cherry Angiomas (Senile Angiomas, de Morgan Spots)......Page 685 Capillary Malformations......Page 686 Reticulated Port Wine Stains......Page 687 Sturge-Weber Syndrome......Page 688 Capillary Malformation–Arteriovenous Malformation......Page 689 Several Syndromes Associated with Venous Malformations......Page 690 Glomus Tumor......Page 691 Other Lesions......Page 692 Microcystic Lymphatic Malformation (Lymphangioma Circumscriptum)......Page 693 Acquired Progressive Lymphangioma (Benign Lymphangioendothelioma)......Page 694 Capillary Aneurysms......Page 695 Unilateral Nevoid Telangiectasia......Page 696 Angiolymphoid Hyperplasia with Eosinophilia......Page 697 Angioma Serpiginosum......Page 698 Classic Kaposi Sarcoma.......Page 699 Treatment.......Page 700 Angiosarcoma......Page 701 Keloid......Page 702 Knuckle Pads......Page 703 Infantile Myofibromatosis......Page 704 Fibromatosis Colli......Page 705 Connective Tissue Nevi......Page 706 Fibrous Papule of Nose (Fibrous Papule of Face, Benign Solitary Fibrous Papule)......Page 707 Oral Submucous Fibrosis......Page 708 Dermatofibroma (Fibrous Histiocytoma)......Page 709 Nodular Fasciitis (Nodular Pseudosarcomatous Fasciitis)......Page 710 Atypical Fibroxanthoma......Page 711 Epithelioid Sarcoma......Page 712 Clinical Classification......Page 713 Systemic Mastocytosis......Page 714 Biochemical Studies......Page 715 Treatment......Page 716 Neuroma Cutis......Page 717 Schwannoma (Neurilemmoma)......Page 718 Cutaneous Meningioma......Page 719 Lipomas......Page 720 Subtypes......Page 721 Multiple Cutaneous Leiomyomas......Page 722 Congenital Smooth Muscle Hamartoma......Page 723 Metastatic Carcinoma......Page 724 Paraneoplastic Syndromes......Page 725 Treatment......Page 726 Keratinocytic Epidermal Nevi......Page 735 Epidermal Nevus Syndrome......Page 736 Inflammatory Linear Verrucous Epidermal Nevus......Page 737 Clear Cell Acanthoma (Pale Cell Acanthoma)......Page 738 Seborrheic Keratosis......Page 739 Dermatosis Papulosa Nigra......Page 740 Benign Lichenoid Keratoses (Lichen Planus–Like Keratosis)......Page 741 Nonmelanoma Skin Cancers and Their Precursors......Page 742 Actinic Keratosis (Solar Keratosis)......Page 743 Cutaneous Horn (Cornu Cutaneum)......Page 744 Histopathology......Page 745 Keratoacanthoma Centrifugum Marginatum......Page 746 Morpheaform, or Cicatricial Basal Cell Carcinoma......Page 747 Porelike Basal Cell Carcinoma......Page 748 Histopathology......Page 749 Topical Therapy......Page 750 Skeletal Defects/Birth Defects......Page 751 Clinical Features......Page 752 Differential Diagnosis......Page 753 Verrucous Carcinoma (Carcinoma Cuniculatum)......Page 754 Histopathology......Page 755 Erythroplasia of Queyrat......Page 756 Balanitis Plasmacellularis (Zoon Balanitis)......Page 757 Extramammary Paget Disease......Page 758 Merkel Cell Carcinoma (Trabecular Carcinoma)......Page 760 Nevus Sebaceus (Organoid Nevus)......Page 761 Sebaceous Hyperplasia......Page 762 Muir-Torre Syndrome......Page 763 Syringoma......Page 764 Acrospiromas (Poroma, Hidroacanthoma Simplex, Dermal Duct Tumor, Nodular Hidradenoma, Clear Cell Hidradenoma)......Page 765 Spiradenoma......Page 766 Cylindroma......Page 767 Syringadenoma Papilliferum (Syringocystadenoma Papilliferum)......Page 768 Microcystic Adnexal Carcinoma (Sclerosing Sweat Duct Carcinoma)......Page 769 Aggressive Digital Papillary Adenocarcinoma (Digital Papillary Adenocarcinoma)......Page 770 Malignant Pilomatricoma (Pilomatrix Carcinoma, Pilomatrical Carcinoma)......Page 771 Brooke-Spiegler Syndrome (Multiple Familial Trichoepithelioma, Epithelioma Adenoides Cysticum)......Page 772 Trichilemmoma and Cowden Syndrome (Cowden Disease, Multiple Hamartoma Syndrome)......Page 773 Trichodiscoma, Fibrofolliculoma, Perifollicular Fibromas, Mantleomas, and Birt-Hogg-Dubé Syndrome......Page 775 Basaloid Follicular Hamartoma......Page 776 Epidermal Cyst (Epidermal Inclusion Cyst, Infundibular Cyst)......Page 777 Proliferating Trichilemmal Cyst/Malignant Trichilemmal Cyst......Page 778 Dermoid Cyst......Page 779 Steatocystoma Multiplex......Page 780 Milia......Page 781 Bronchogenic Cysts......Page 782 Congenital Preauricular Fistula......Page 783 Solar Lentigo (Lentigo Senilis)......Page 792 Centrofacial Lentiginosis......Page 793 Melanoacanthoma......Page 794 Malignant Degeneration......Page 795 Halo Nevus......Page 796 Small and Medium-Sized Congenital Nevocytic Nevus......Page 797 Spindle and Epithelioid Cell Nevus (Spitz Nevus)......Page 798 Atypical Nevus (Dysplastic Nevus, Clark Nevus)......Page 799 Lentigo Maligna (Lentiginous Melanoma on Sun-Damaged Skin)......Page 801 Acral-Lentiginous Melanoma......Page 802 Differential Diagnosis......Page 803 Metastasis......Page 804 Prognosis......Page 805 Treatment......Page 806 Dermal Melanocytosis......Page 807 Cellular Blue Nevus......Page 808 Treatment......Page 809 Subcutaneous Granuloma Annulare (Deep Granuloma Annulare, Pseudorheumatoid Nodule)......Page 815 Palmar Granuloma Annulare/Acute-Onset Painful Acral Granuloma Annulare......Page 816 Treatment......Page 817 Annular Elastolytic Giant Cell Granuloma (Meischer), Annular Elastolytic Granuloma, and Actinic Granuloma (O’brien)......Page 819 Necrobiotic Xanthogranuloma......Page 820 Annular Sarcoidosis......Page 822 Ulcerative Sarcoidosis......Page 823 Alopecia......Page 824 Systemic Sarcoidosis......Page 825 Histopathology......Page 826 Treatment......Page 827 Non-Langerhans Cell (X-type) Histiocytosis......Page 829 Juvenile Xanthogranuloma......Page 830 Generalized Eruptive Histiocytoma (Generalized Eruptive Histiocytosis)......Page 832 Progressive Nodular Histiocytosis......Page 833 Progressive Mucinous Histiocytosis in Women......Page 834 Multicentric Reticulohistiocytosis.......Page 835 Indeterminate Cell Histiocytosis......Page 836 Langerhans Cell Histiocytosis (X-Type Histiocytoses)......Page 837 Skin Lesions.......Page 838 Bony Lesions.......Page 839 Treatment and Prognosis.......Page 840 Cutaneous Lymphoid Hyperplasias—Bandlike T-Cell Pattern......Page 844 Natural History.......Page 845 Clinical Features.......Page 846 Alopecia Mucinosa.......Page 847 Histopathology.......Page 848 Ultraviolet Therapy.......Page 849 Pagetoid Reticulosis......Page 850 Lymphomatoid Papulosis......Page 851 Pityriasis Lichenoides Et Varioliformis Acuta (Mucha-Habermann Disease)......Page 852 CD30+ Cutaneous T-Cell Lymphoma (Primary Cutaneous Anaplastic Large Cell Lymphoma)......Page 853 Subcutaneous (Panniculitis-Like) T-Cell Lymphoma......Page 854 Adult T-Cell Leukemia/Lymphoma......Page 855 Primary Cutaneous Follicle Center Cell Lymphoma (PCFCCL, Diffuse and Follicular Types)......Page 856 Plasmacytoma (Multiple Myeloma)......Page 857 Malignant Histiocytosis (Histiocytic Medullary Reticulosis)......Page 858 Specific Eruptions......Page 859 Cutaneous Myelofibrosis......Page 860 Sinus Histiocytosis With Massive Lymphadenopathy (Rosai-Dorfman Disease)......Page 861 Polycythemia Vera (Erythremia)......Page 862 Etiologic Factors.......Page 867 Treatment.......Page 868 Telogen Effluvium......Page 869 Anagen Effluvium......Page 870 Male-Pattern Baldness.......Page 871 Trichotillosis......Page 872 Other Forms of Noncicatricial Alopecia......Page 873 Cicatricial Alopecia......Page 874 Lupus Erythematosus......Page 875 Central Centrifugal Cicatricial Alopecia......Page 876 Tufted Folliculitis......Page 877 Tumor Alopecia......Page 878 Hair Color......Page 879 Pili Torti......Page 880 Trichorrhexis Nodosa......Page 881 Monilethrix......Page 882 Kinking Hair......Page 883 Pseudofolliculitis Barbae......Page 884 Trichostasis Spinulosa......Page 885 Generalized or Patterned Acquired Hypertrichosis......Page 886 Pathogenesis......Page 887 Treatment......Page 888 Tinea Amiantacea (Pityriasis Amiantacea)......Page 889 Traumatic Anserine Folliculosis......Page 890 Generalized Hyperhidrosis......Page 891 Surgical Treatment.......Page 892 Bromhidrosis......Page 893 Fox-Fordyce Disease......Page 894 Diseases of the Nails......Page 895 Psoriatic Nails......Page 896 Clubbing......Page 897 Congenital Onychodysplasia of Index Fingers......Page 898 Onychomadesis......Page 899 Me

Now in a fully revised thirteenth edition, Andrews’ Diseases of the Skin remains your single-volume, must-have resource for core information in dermatology. From residency through clinical practice, this award-winning title ensures that you stay up to date with new tools and strategies for diagnosis and treatment, new entities and newly recognized diseases, and current uses for tried-and-true and newer medications. It’s the reference you’ll turn to again and again when faced with a clinical conundrum or therapeutically challenging skin disease.

• Utilizes a concise, clinically focused, user-friendly format that clearly covers the full range of common and rare skin diseases.
• Provides outstanding visual support with 1,340 illustrations – more than 500 new to this edition.
• Presents comprehensively updated information throughout, including new and unusual clinical presentations of syphilis, new diagnostic classifications and therapies for vascular anomalies, and an updated pediatric and genodermatosis review.
• Covers new and evolving treatments for inflammatory, neoplastic, and blistering skin diseases among others. New biologics and phosphodiesterase inhibitors for psoriasis and atopic dermatitis, JAK inhibitors for alopecia areata and vitiligo, immune checkpoint inhibitors for melanoma and rituximab for pemphigus are all covered.
• Features a revised and revamped cutaneous adverse drug reaction section, including novel eruptions from new and emerging chemotherapeutic agents and small molecule/targeted inhibitors.
• Discusses new and emerging viruses including Zika and human polyomaviruses.

From residency through clinical practice, this award-winning title ensures that you stay up to date with new tools and strategies for diagnosis and treatment, new entities and newly recognized diseases, and current uses for tried-and-true and newer medications. It's the reference you'll turn to again and again when faced with a clinical conundrum or therapeutically challenging skin disease. Key Features: Utilizes a concise, clinically focused, user-friendly format that clearly covers the full range of common and rare skin diseases; Provides access to approximately 20 videos online, depicting chemical peels, Q-switched laser tattoo removal, ED & C (electrodesiccation and curettage), nerve block, and more; Presents comprehensively updated information throughout, including new and unusual clinical presentations of syphilis, new diagnostic classifications and therapies for vascular anomalies, and an updated pediatric and genodermatosis review; Covers new and evolving treatments for inflammatory, neoplastic, and blistering skin diseases among others. New biologics and phosphodiesterase inhibitors for psoriasis and atopic dermatitis, JAK inhibitors for alopecia areata and vitiligo, immune checkpoint inhibitors for melanoma and rituximab for pemphigus are all covered; Features a revised and revamped cutaneous adverse drug reaction section, including novel eruptions from new and emerging chemotherapeutic agents and small molecule/targeted inhibitors; Discusses new and emerging viruses including Zika and human polyomaviruses. -- Publisher