The Ischemic Penumbra: Pathophysiology, Imaging and Therapy (Neurological Disease and Therapy Book 93)

This source presents the current status of concepts and research on ischemic penumbra and identifies the latest methods for clinicians to quickly and efficiently recognize viable cerebral tissue for enhanced stroke management. Focusing on state-of-the-science technologies and cutting-edge trends, this guide examines imaging strategies utilizing PET, SPECT, MR, and CT for improved identification of key areas for intervention and therapy in the management of stroke patients. The ischemic penumbra : the beginning / Lindsay Symon The ischemic penumbra : overview, definition, and criteria / Geoffrey A. Donnan ... [et al.] Perfusion thresholds in cerebral ischemia / Ramez R. Moustafa and Jean-Claude Baron Duration and thresholds of the ischemic penumbra in different species / Omar Touzani and Jean-Claude Baron The ischemic cascade : events within the penumbra / Juliane Klehmet ... [et al.] Multimodal mapping of the ischemic penumbra in animal models / Konstantin-A. Hossmann and Günter Mies Molecular biology of the penumbra / Frank R. Sharp ... [et al.] Selective neuronal loss / Anthony J. Strong, Anna M. Planas Inflammation and reperfusion injury within the penumbra / Adrian Parry-Jones ... [et al.] Imaging penumbra and neuronal loss : positron emission tomography with Flumazenil / Wolf-Dieter Heiss ... [et al.] Imaging the penumbra : positron emission tomography fluoromisonidazole / Neil J. Spratt, David W. Howells, and Geoffrey A. Donnan Can the penumbra be imaged using single-photon emission computed tomography? / Toshihiro Ueda Magnetic resonance imaging assessment of the ischemic penumbra in experimental stroke / Timothy Q. Duong and Marc Fisher Penumbra imaged with magnetic resonance imaging in humans / Chelsea S. Kidwell and Steven Warach Perfusion computed tomography and xenon-computed tomography : current status and implications for therapy. Perfusion computed tomography / Patrik Michel, Max Wintermark, and Julien Bogousslavsky ; Xenon-computed tomography-cerebral blood flow assessment of ischemic penumbra in acute stroke / Tudor G. Jovin ... [et al.] Magnetic resonance imaging of ischemic penumbra : new techniques. Gradient echo / Jun Hatazawa and Eku Shimosegawa ; "Penumbra" defined by magnetic resonance imaging : oxygen extraction fraction and cerebral metabolic rate of oxygen utilization / Weili Lin ... [et al.] ; Arterial spin labeling / John A. Detre and Timothy Q. Duong Clinical/imaging mismatch as an index of the penumbra / Jane F. Prosser, Antoni Davalos, and Stephen M. Davis The topography of the ischemic penumbra / Romesh Markus, David Reutens, and Geoffrey A. Donnan The penumbra and intracerebral hemorrhage / Ken Butcher and Romesh Markus Extending the time window for therapy / Numthip Chitravas and Geoffrey A. Donnan Magnetic resonance in the selection of stroke therapies / Stephen M. Davis, Joachim Röther, and Geoffrey A. Donnan. The Ischemic Penumbra presents the current status of concepts and research on this topic and identifies the latest methods for clinicians to quickly and efficiently recognize viable cerebral tissue for enhanced stroke management. Focusing on state-of-the-science technologies and current trends, the book examines imaging strategies utilizing PET, SPECT, MR, and CT for improved identification of key areas for intervention and therapy in the management of stroke patients. With chapters by international authorities on the topicâ€"including the originator of the ischemic penumbra concept, Profe