The inflammatory process

The Inflammatory Process focuses on the approaches, methodologies, and technologies involved in the study of the inflammatory process, including capillary structure, tissue injury, and inflammatory response. The selection first offers information on the experimental approach to inflammation, ultrastructural and biochemical consequences of cell injury, and ultrastructural basis of capillary permeability. Discussions focus on permeability of capillaries, cytoplasm, nucleus, gross pathology of inflammation, light microscope and the study of inflammation, and the physiologic approach to problems of inflammation. The text then elaborates on the microvascular aspects of tissue injury and the sticking and emigration of white blood cells in inflammation. The book examines neutrophil and eosinophil leucocytes,'life history'and functions of lymphocytes, and metabolism and physiology of mononuclear phagocytes. Topics include inflammatory response, biochemistry and metabolism, special relationships to bacteria and viruses, and origins and early development of lymphocytes. The text also ponders on the role of lysosomes in tissue injury, hemostatic mechanisms in tissue injury, and anti-inflammatory agents. The selection is a vital source of data for researchers interested in the inflammatory process. Content: Front Matter, Page iii Copyright, Page iv Contributors, Pages v-vi Preface, Pages vii-viii, BENJAMIN W. ZWEIFACH, LESTER GRANT, ROBERT T. MGCLUSKEY CHAPTER 1 - The Experimental Approach to Inflammation, Pages 1-33, ROBERT H. EBERT CHAPTER 2 - Some Ultrastructural and Biochemical Consequences of Cell Injury, Pages 35-120, BENJAMIN F. TRUMP, JAN L.E. ERICSSON CHAPTER 3 - The Ultrastructural Basis of Capillary Permeability, Pages 121-159, JOHN H. LUFT CHAPTER 4 - Microvascular Aspects of Tissue Injury, Pages 161-196, BENJAMIN W. ZWEIFACH CHAPTER 5 - The Sticking and Emigration of White Blood Cells in Inflammation, Pages 197-244, LESTER GRANT CHAPTER 6 - Neutrophil and Eosinophil Leucocytes, Pages 245-280, JAMES G. HIRSCH CHAPTER 7 - The “Life History” and Functions of Lymphocytes, Pages 281-322, BERTRAM M. GESNER CHAPTER 8 - The Metabolism and Physiology of the Mononuclear Phagocytes, Pages 323-353, ZANVIL A. COHN CHAPTER 9 - Structural and Biochemical Characteristics of Mast Cells, Pages 355-388, GUNNAR D. BLOOM CHAPTER 10 - Chemical Mediators. I, Pages 389-425, D.L. WILHELM CHAPTER 11 - Chemical Mediators. II, Pages 427-448, W.G. SPECTOR, D.A. WILLOUGHBY CHAPTER 12 - The Role of Lysosomes in Tissue Injury, Pages 449-463, LEWIS THOMAS CHAPTER 13 - Hemostatic Mechanisms in Tissue Injury, Pages 465-494, R.G. MACFARLANE CHAPTER 14 - Fever, Pages 495-534, ELISHA ATKINS, E.S. SNELL CHAPTER 15 - Fibroplasia: A Sequel to Lymphocyte Exudation, Pages 535-557, ALLAN E. DUMONT CHAPTER 16 - Anti-Inflammatory Agents, Pages 559-576, FRED ALLISON JR. CHAPTER 17 - Delayed Hypersensitivity, Pages 577-586, B. BENACERRAF CHAPTER 18 - Anaphylaxis: Systemic, Local Cutaneous, and In Vitro, Pages 587-612, K. FRANK AUSTEN CHAPTER 19 - The Arthus Reaction, Pages 613-648, CHARLES G. COCHRANE CHAPTER 20 - Experimental Serum Sickness, Pages 649-683, ROBERT T. McCLUSKEY CHAPTER 21 - Inflammation in Homograft Rejection, Pages 685-730, RUY PÉREZ-TAMAYO, ROBERTO R. KRETSCHMER CHAPTER 22 - Autoimmune Diseases, Pages 731-762, NOEL R. ROSE CHAPTER 23 - The Cellular Basis of Antibody Formation, Pages 763-789, JONATHAN W. UHR CHAPTER 24 - The Local and Generalized Shwartzman Phenomena, Pages 791-817, LEUNG LEE, CHANDLER A. STETSON JR. CHAPTER 25 - The Role of Complement in Immune Phenomena, Pages 819-872, ROBERT A. NELSON JR. Contributors: Biographical Sketches, Pages 873-876 Author Index, Pages 877-918 Subject Index, Pages 919-931