The Human Hypothalamus: Middle and Posterior Region (Volume 180) (Handbook of Clinical Neurology, Volume 180)

The Hypothalamus is an important area of the brain for understanding a variety of neurological disorders. This volume summarizes for readers the anatomy and physiology of the middle and posterior hypothalamus, to better understand pathology and treatment of hypothalamus related disorders. In addition to anatomy and physiology in humans, cytoarchitecture and chemoarchitecture in rodents is provided. The volume explores the role of the hypothalamus in disorders of eating, sleeping, anxiety, and mood, as well as its role in sexual behavior and gender identity. Coverage includes how Parkinson's, Alzheimer's and other neurological disorders relate to the hypothalamus. Reviews the anatomy and physiology of the middle and posterior hypothalmus Provides cytoarchitecture and chemoarchitecture from rodents Discusses hypothalamic related disorders of eating, sleeping, anxiety, and mood Covers how Parkinson's, Alzheimer's and other neurological disorders relate to the hypothalamus Explores the role of the hypothalamus in sexual behavior and gender identity Foreword Preface Contributors Contents 1. Introduction: The middle and posterior hypothalamus • D.F. Swaab, F. Kreier, P.J. Lucassen, A. Salehi, and R.M. Buijs Section 6: Supraoptic and paraventricular nucleus more than a neuroendocrine system 2. Vasopressin and oxytocin beyond the pituitary in the human brain • M. Møller 3. Central and peripheral release of oxytocin: Relevance of neuroendocrine and neurotransmitter actions for physiology and behavior • F. Althammer, M. Eliava, and V. Grinevich 4. Organization of the neuroendocrine and autonomic hypothalamic paraventricular nucleus • A. Kalsbeek and R.M. Buijs 5. Sex differences of oxytocin and vasopressin in social behaviors • Q. Lu and S. Hu 6. Oxytocin, eating behavior, and metabolism in humans • L. Kerem and E.A. Lawson 7. The supraoptic and paraventricular nuclei in healthy aging and neurodegeneration • C.A. Stewart and E.C. Finger 8. Perinatal stress and epigenetics • M. Szyf 9. The hypothalamus in anxiety disorders • S. Fischer 10. Congenital isolated central hypothyroidism: Novel mutations and their functional implications • A. Boelen, A.S.P. van Trotsenburg, and E. Fliers Section 7: Zona incerta 11. The zona incerta system: Involvement in attention and movement • S. Chometton, M. Barbier, and P.-Y. Risold Section 8: Ventromedial nucleus and dorsomedial nucleus 12. The role of the dorsomedial and ventromedial hypothalamus in regulating behaviorally coupled and resting autonomic drive • L.A. Henderson and V.G. Macefield 13. The subfornical organ and organum vasculosum of the lamina terminalis: Critical roles in cardiovascular regulation and the control of fluid balance • W.M. Fry and A.V. Ferguson 14. Lamina terminalis fenestration: An important neurosurgical corridor • C. Giussani and A. Di Cristofori 15. Arcuate nucleus, median eminence, and hypophysial pars tuberalis • H.-W. Korf and M. Møller 16. Tanycytes in the infundibular nucleus and median eminence and their role in the blood–brain barrier • V. Prevot, R. Nogueiras, and M. Schwaninger 17. The human hypothalamic kisspeptin system: Functional neuroanatomy and clinical perspectives • E. Hrabovszky, S. Takács, E. Rumpler, and K. Skrapits 18. Kisspeptin and neurokinin B expression in the human hypothalamus: Relation to reproduction and gender identity • J. Bakker 19. The infundibular peptidergic neurons and glia cells in overeating, obesity, and diabetes • M.J.T. Kalsbeek and C.-X. Yi 20. Hypothalamus and weight loss in amyotrophic lateral sclerosis • R.M. Ahmed, F. Steyn, and L. Dupuis Section 10: Lateral tuberal nucleus Section 11: Lateral hypothalamic area, perifornical area 21. The orexin/hypocretin system in neuropsychiatric disorders: Relation to signs and symptoms • R. Fronczek, M. Schinkelshoek, L. Shan, and G.J. Lammers 22. Pleasure, addiction, and hypocretin (orexin) • R. McGregor, T.C. Thannickal, and J.M. Siegel Section 12: Tuberomamillary complex 23. Histamine receptors, agonists, and antagonists in health and disease • P. Panula 24. The tuberomamillary nucleus in neuropsychiatric disorders • L. Shan, R. Fronczek, G.J. Lammers, and D.F. Swaab Section 13: Subthalamic nucleus 25. Imaging of the human subthalamic nucleus • A. Alkemade and B.U. Forstmann 26. Neuropsychiatric effects of subthalamic deep brain stimulation • P.E. Mosley and H. Akram 27. The subthalamic nucleus and the placebo effect in Parkinson's disease • E. Frisaldi, D.A. Zamfira, and F. Benedetti Section 14: Corpora mamillaria, fornix, and mamillothalamic tract 28. Electrical stimulation of the fornix for the treatment of brain diseases • S. Hescham and Y. Temel 29. The contribution of mamillary body damage to Wernicke's encephalopathy and Korsakoff's syndrome • N.J.M. Arts, A.-L. Pitel, and R.P.C. Kessels Index