The Heart in Hypertension : A Tribute to Robert Tarazi (1925–1986)

**`**... this very well structured and well-edited volume. The present book gives an outstanding overview of his (Robert Tarazi) favourite research topic ... to recommend it to everyone involved in hypertension research and care of hypertensive patients.**'****Cardiology**, 77/4, 1990 Front Matter....Pages I-XIV Front Matter....Pages 1-1 A tribute to Robert C. Tarazi, M.D. (1925–1986)....Pages 3-3 The multifaceted aspects of cardiac involvement in hypertension....Pages 5-12 Front Matter....Pages 13-13 Cardiac output in hypertension....Pages 15-25 Haemodynamic development....Pages 27-35 Systemic hemodynamics and aging....Pages 37-45 The hemodynamics of borderline hypertension....Pages 47-66 Systemic hemodynamics in sustained essential and reno-vascular hypertension....Pages 67-78 Systemic hemodynamics in primary aldosteronism....Pages 79-85 Systemic hemodynamics in patients with pheochromocytoma....Pages 87-96 Systemic hemodynamics in renal parenchymal disease....Pages 97-103 Hemodynamics in patients with overweight and hypertension....Pages 105-122 Atherosclerotic hypertension....Pages 123-133 Postmyocardial revascularization hypertension....Pages 135-142 Front Matter....Pages 143-143 Cardiac structure and function in animal models and in human hypertension....Pages 145-164 Volume and cardiac factors in the genesis of mineralocorticoid hypertension in the conscious dog....Pages 165-168 Heart and hypertension: The magnitude of the problem....Pages 169-178 Acute volume expansion and pumping function of the heart in sustained essential hypertension....Pages 179-187 Systolic function and inotropism of the heart in borderline and sustained essential hypertension....Pages 189-200 Left ventricular diastolic function in hypertension....Pages 201-207 The right ventricle and the lesser circulation in essential hypertension....Pages 209-220 Front Matter....Pages 143-143 Management of hypertensive patients with cardiac problems....Pages 221-239 Front Matter....Pages 241-241 Coronary circulation, cardiac hypertrophy, and myocardial ischemia....Pages 243-251 Coronary circulation and coronary reserve in the hypertensive heart....Pages 253-269 Hypertension and coronary atherosclerosis....Pages 271-280 Clinical trials, coronary insufficiency, and large arteries in hypertension....Pages 281-292 Front Matter....Pages 293-293 Left ventricular hypertrophy and its reversion in hypertension....Pages 295-300 Regression of cardiac hypertrophy: Experimental animal model....Pages 301-308 Cardiac structure and function after treatment with adrenergic blocking agents....Pages 309-323 Cardiac structure and function after vasodilating drugs (dihydralazine-minoxidil)....Pages 325-331 The effect of converting enzyme inhibitors on the hemodynamic profile of hypertension....Pages 333-339 Cardiovascular structure and function after treatment with calcium entry inhibitors in hypertension....Pages 341-346 Front Matter....Pages 347-347 Baroreceptor mechanisms and the control of vascular resistance....Pages 349-361 Structural changes of small resistance vessels in essential hypertension....Pages 363-370 Hemodynamic response to exercise in hypertension and its modulation by anti-hypertensive therapy....Pages 371-394 Reversion of cardiac, arteriolar and arterial changes following antihypertensive treatment....Pages 395-415 Front Matter....Pages 417-417 The heart in hypertension: mechanical and humoral factors....Pages 419-429 Back Matter....Pages 431-436 Hypertension is the major cause of left ventricular hypertrophy. While the electrocardiogram is an extremely insensitive measure of anatomic left ven tricular hypertrophy, it provides a time-tested important marker of an adverse cardiovascular outcome. There has been a recent temporal decrease in the incidence of electrocardiographic evidence of L VH even within the hyperten sive population; no doubt this is the result of large antihypertensive treatment experts. Anatomical evidence of left ventricular hypertrophy is best docu mented pre-morbidly using echocardiographic techniques. It therefore ap pears that between 20 and 50 percent of the hypertensive population has left ventricular hypertrophy by echo cardiographic techniques. The prognostic significance of the echocardiographically determined increase in left ventric ular mass is just beginning to be evaluated. Early information suggests that there is an increased rate of cardi~)Vascular morbidity in patients with echo car diographic evidence of increased left ventricular mass. However, this in formation is only preliminary, and as yet only a limited number of events have been reported. Far more supporting information will be required before the full impact of echocardiographically-detected left ventricular hypertrophy can be determined. Nevertheless, it must be stated that the electrocardiogram still has the greatest predictive value of cardiovascular morbid and mortal events when the pattern of left ventricular hypertrophy plus repolarization abnormal ities are present ` ... this very well structured and well-edited volume. The present book gives an outstanding overview of his (Robert Tarazi) favourite research topic ... to recommend it to everyone involved in hypertension research and care of hypertensive patients. ' Cardiology , 77/4, 1990