The Handbook of Alzheimer's Disease and Other Dementias

The reference is a broad-ranging review of Alzheimer's disease and other dementias from both basic and clinical neuroscience perspectives; it provides scientists and medical professionals with an extensive introduction and an up-to-date review of cutting-edge scientific advances. Brings the reader up-to-date with cutting-edge developments in this exciting and fast-paced field Summarizes the most recent developments in the fields of Alzheimer's disease and dementia Brings together articles from a prominent and international group of contributors Encompasses a unique range of topics, combining basic molecular perspectives and cognitive neurosciences The Handbook of Alzheimer’s Disease and Other Dementias......Page 5 Contents......Page 9 Contributors......Page 11 Foreword......Page 14 Preface......Page 17 Part I: Common Dementias......Page 19 1: Alzheimer’s Disease......Page 21 2: Vascular Dementia......Page 110 3: Dementia with Lewy Bodies......Page 149 4: Frontotemporal Dementia......Page 163 5: Other Dementias......Page 197 Part II: Pathogenesis and Disease Mechanisms......Page 213 6: Genetic Risk Factors for Dementia......Page 215 7: The Neuropathology of the Dementing Disorders......Page 253 8: Amyloid Beta Peptide and the Amyloid Cascade Hypothesis......Page 280 9: Other Mechanisms of Neurodegeneration......Page 295 10: Rational Therapeutics for Alzheimer’s Disease and Other Dementias......Page 319 Part III: Cognitive and Behavioral Dysfunction......Page 331 11: Memory Dysfunction in Dementia......Page 333 12: Language Processing in Dementia......Page 354 13: Executive Functioning......Page 387 14: Emotion and Behavior in Alzheimer’s Disease and Other Dementias......Page 434 15: Visuospatial Function in Alzheimer’s Disease and Related Disorders......Page 475 16: Sleep and Circadian Rhythms in Dementia......Page 501 Part IV: Neuroimaging in Dementia......Page 523 17: Glimpses of the Living Brain with Alzheimer’s Disease......Page 525 18: Functional MRI in Alzheimer’s Disease and Other Dementias......Page 553 19: Molecular Neuroimaging of the Dementias......Page 575 20: Using EEG and MEG to Understand Brain Physiology in Alzheimer’s Disease and Related Dementias......Page 593 Index......Page 622 Color Plates......Page 649 Alzheimer's disease / by Alan M. Mandell and Robert C. Green Vascular dementia / by Angela L. Jefferson, Amanda M. Gentile, and Ravi Kahlon Dementia with Lewy bodies / by Tamara G. Fong and Daniel Press Frontotemporal dementia / by Adam L. Boxer Other causes of dementia / by Peter Morin Genetic risk factors for dementia / by Paul Hollingworth and Julie Williams The neuropathology of the dementing disorders / by Ann C McKee and Brandon E. Gavett Amyloid beta peptide and the amyloid cascade hypothesis / by Carmela R. Abraham Other mechanisms of neurodegeneration / by Marina Boziki, Vassilis Papaliagkas, and MagdaTsolaki Rational therapeutics in dementia / by Neil W. Kowall Memory systems in dementia / by Andrew E. Budson Language processing in dementia / by Jamie Reilly, Joshua Troche, and Murray Grossman Executive functioning in dementia / by Robert A. Stern, Stacy L. Andersen, and Brandon E. Gavett Emotion and behavior in Alzheimer's disease and other dementias / by Christopher I. Wright Visuospatial function in Alzheimer's disease and related disorders / by Alice Cronin-Golomb Sleep and circadian rhythms in dementia / by David G. Harper Glimpses of the living brain with Alzheimer's disease / by Ronald J. Killiany Functional MRI in Alzheimer's disease and other dementias / by Maija Pihlajamäki & Reisa A. Sperling Molecular neuroimaging of the dementias: from scientific insights to clinical applications / by Bradford C. Dickerson Using EEG and MEG to understand brain physiology in Alzheimer's disease and related dementias / by Brandon A. Ally. "The reference is a broad-ranging review of Alzheimer's disease and other dementias from both basic and clinical neuroscience perspectives; it provides scientists and medical professionals with an extensive introduction and an up-to-date review of cutting-edge scientific advances. Brings the reader up-to-date with cutting-edge developments in this exciting and fast-paced field -- Summarizes the most recent developments in the fields of Alzheimer's disease and dementia -- Brings together articles from a prominent and international group of contributors -- Encompasses a unique range of topics, combining basic molecular perspectives and cognitive neurosciences."--Provided by publisher The reference is a broad-ranging review of Alzheimer's disease and other dementias from both basic and clinical neuroscience perspectives; it provides scientists and medical professionals with an extensive introduction and an up-to-date review of cutting-edge scientific advances. Brings the reader up-to-date with cutting-edge developments in this exciting and fast-paced field Summarizes the most recent developments in the fields of Alzheimer's disease and dementia Brings together articles from a prominent and international group of contributors Encompasses a unique range of topics, combining basic molecular perspectives and cognitive neurosciences --[Résumé de l'éditeur] This is a broad-ranging review of the current research on Alzheimer's disease and other dementias from both basic neuroscience and clinical perspectives. It provides scientists and medical professionals with an extensive introduction and an up-to-date review of cutting-edge scientific advances in a single volume.