The Genetics of Renal Disease (Oxford Monographs on Medical Genetics, No. 48)

Guy's Hospital, London, UK. Provides a comprehensive account of the hereditary nephropathies and more generalized disorders which may affect the renal tract. Previously published as The Genetics of Renal Tract Disorders, by M. D'A Crawfurd, c1988. For clinical geneticists and researchers. Illustrated. Provides A Comprehensive Account Of Both The Hereditary Neuropathies And More Generalized Disorders Which May Affect The Renal Tract. Specific Chapters Deal With Individual Renal Tract Disorders Such As An Extensive Discussion Of Alport Syndrome, Cystic Renal Diseases, And Bardet-biedl And Alstrom Syndromes. Each Section Gives A Brief Description Of The Clinical And Pathological Features Of A Particular Disorder, Followed By A Review Of The Genetics Of The Disorder, Including Its Incidence, The Pattern Of Inheritance, Genetic Linkage And Gene Assignment, And Carrier Detection And Prenatal Diagnosis. 1. Introduction To Clinical Genetics / Shehla Mohammed -- 2. Renal Function And Management Of Renal Disease / A. David Makanjuola And John E. Scoble -- 3. Renal Development / Paul J. D. Winyard -- 4. Kidney And Lower Urinary Tract Malformations / Adrian S. Woolf -- 5. Urinary Tract Defects And Chromosomal Disorders / David J. Amor, Lachlan De Crespigny And R. J. Mckinlay Gardner -- 6. Dysmorphic Syndromes With Renal Involvement / Ian D. Young -- 7. Primary Hereditary Nephropathies / Karl Tryggvason -- 8. Alport Syndrome / Frances Flinter -- 9. Autosomal Dominant Polycystic Kidney Disease / Anand K. Saggar-malik And Stefan Somlo -- 10. Autosomal Recessive Polycystic Kidney Disease / Lisa M. Guay-woodford -- 11. Cystic Renal Diseases / Anand K. Saggar-malik -- 12. Primary Inherited Metabolic Diseases Of The Kidney / Margaret Town And William Van't Hoff -- 13. Genetics Of Stone Forming Diseases / Pasquale Strazzullo And Pietro Vuotto -- 14. Disorders Of Tubular Transport / David S. Geller, Mark A. J. Devonald And Fiona E. Karet -- 15. Tuberous Sclerosis Complex / Astrid P. Weber And Robert F. Mueller -- 16. Neurofibromatosis / Susan M. Huson And Natalie Canham -- 17. The Bardet-biedl And Alstrom Syndromes / Philip L. Beales, Patrick S. Parfrey And Nicholas Katsanis -- 18. Genetic Syndromes With A Renal Component / Richard Sandford And Robin G. Woolfson -- 19. The Genetics Of Glomerulonephritis And Systemic Disorders Affecting The Kidney / Stephen H. Powis -- 20. Wilms Tumour And The Wilms Tumour Predisposition Syndromes / Richard Grundy -- 21. Von Hippel-lindau Disease / Eamonn R. Maher -- 22. Inherited Predispositions To Kidney Cancer / Berton Zbar, Gladys Glenn, Maria Turner, Gregor Weirich, Peter Choyke, Stephen Hewitt, Michael Nickerson, Naboru Nakaigawa, W. Marston Linehan And Laura Schmidt -- 23. Gene Therapy In Renal Disease / Anand K. Saggar-malik -- 24. Gene Therapy For Renal Cancer / Michael J. Gough And Richard G. Vile. Edited By Frances Flinter, Eamonn Maher, Anand Saggar-malik. Previously Published As The Genetics Of Renal Tract Disorders, By M. D'a. Crawfurd, 1988--t.p. Verso. Includes Bibliographical References And Indexes. Title from ebook title screen (viewed on June 10, 2005).