The Frontal Lobes (Volume 163) (Handbook of Clinical Neurology, Volume 163)

The Frontal Lobes, Volume 163, updates readers on the latest thinking on the structure and function of the human frontal lobe. Sections address methodology, anatomy, physiology and pharmacology, function, development, aging and disorders, and rehabilitation. Patients with focal lesions in the frontal lobes have long been studied to reveal the organization and function of the frontal lobes. Over the last two decades, studies of patients with neurodegenerative diseases and developmental disorders have increased, with new findings discussed in this volume. In addition, the book includes discussions on genetics and molecular biology, optogenetics, high-resolution structural and functional neuroimaging and electrophysiology, and more. Lastly, new knowledge on the biology, structure and function of the frontal lobes, new treatment targets for pharmacology, non-invasive brain stimulation, and cognitive/social remediation are presented. The last section covers new efforts that will hopefully lead to better outcomes in patients with frontal lobe disorders Foreword Preface Contributors Contents Section I: History 1. The prefrontal cortex in the neurology clinic • J.M. Fuster Section II: Methods 2. The functions of the frontal lobes: Evidence from patients with focal brain damage • L.K. Fellows 3. Cognitive neurophysiology of the prefrontal cortex • R.F. Helfrich and R.T. Knight 4. Functional imaging • A.S. Kayser 5. Transcranial magnetic stimulation: Neurophysiological and clinical applications • M.J. Burke, P.J. Fried, and A. Pascual-Leone Section III: Anatomy, physiology and pharmacology 6. The anatomy of the human frontal lobe • M. Catani 7. Dopamine and the motivation of cognitive control • R. Cools, M. Frob€ose, E. Aarts, and L. Hofmans Section IV: Function of the frontal lobes 8. Frontal lobe syndromes • J. Reber and D. Tranel 9. Hierarchical cognitive control and the frontal lobes • D. Badre and T.M. Desrochers 10. Hemispheric asymmetry in the prefrontal cortex for complex cognition • V. Goel 11. Executive functions • I. Cristofori, S. Cohen-Zimerman, and J. Grafman 12. The lateral prefrontal cortex and human long-term memory • R.S. Blumenfeld and C. Ranganath 13. From ideas to action: The prefrontal–premotor connections that shape motor behavior • S.T. Grafton and L.J. Volz 14. Emotion regulation across the life span • C. Helion, S.M. Krueger, and K.N. Ochsner 15. Reward • J.D. Wallis 16. Moral conduct and social behavior • R. de Oliveira-Souza and J. Moll 17. Computational models of motivated frontal function • R.C. O’Reilly, J. Russin, and S.A. Herd 18. Control networks of the frontal lobes • S. Marek and N.U.F. Dosenbach Section V: Development, aging, and disorders 19. Development of the frontal lobe • K.S. Rosch and S. Mostofsky 20. Aging of the frontal lobe • T.P. Zanto and A. Gazzaley 21. Neurodegenerative disorders of the human frontal lobes • P.M. Butler and W. Chiong 22. Traumatic brain injury and frontal lobe plasticity • R.A. Bernier and F.G. Hillary Section VI: Rehabilitation 23. Strengthening goal-directed functioning after traumatic brain injury • A.J.-W. Chen and F. Loya 24. Experimental social training methods • P.J. Eslinger, C. Flaherty, and L.A. Eaton 25. Plasticity and recovery of function • R. Quentin, O. Awosika, and L.G. Cohen Index