The evidence base of clinical diagnosis : theory and methods of diagnostic research

This unique book presents a framework for the strategy and methodology of diagnostic research, in relation to its relevance for practice. Now in its second edition The __Evidence Base of Clinical Diagnosis__ has been fully revised and extended with new chapters covering the STARD guidelines (STAndards for the Reporting of Diagnostic accuracy studies) and the multivariable analysis of diagnostic data. With contributions from leading international experts in evidence-based medicine, this book is an indispensable guide on how to conduct and interpret studies in clinical diagnosis. It will serve as a valuable resource for all investigators who want to embark on diagnostic research and for clinicians, practitioners and students who want to learn more about its principles and the relevant methodological options available.Content: Chapter 1 General Introduction: Evaluation of Diagnostic Procedures (pages 1–19): J. Andre Knottnerus, Frank Buntinx and Chris van WeelChapter 2 The Architecture of Diagnostic Research (pages 20–41): R. Brian Haynes and John J. YouChapter 3 Assessment of the Accuracy of Diagnostic Tests: The Cross?Sectional Study (pages 42–62): J. Andre Knottnerus and Jean W. MurisChapter 4 Diagnostic Testing and Prognosis: The Randomized Controlled Trial in Test Evaluation Research (pages 63–82): Jeroen G. Lijmer and Patrick M. M. BossuytChapter 5 The Diagnostic Before–After Study to Assess Clinical Impact (pages 83–95): J. Andre Knottnerus, Geert?Jan Dinant and Onno P. van SchayckChapter 6 Designing Studies to Ensure that Estimates of Test Accuracy Will Travel (pages 96–117): Les M. Irwig, Patrick M. M. Bossuyt, Paul P. Glasziou, Constantine Gatsonis and Jeroen G. LijmerChapter 7 Analysis of Data on the Accuracy of Diagnostic Tests (pages 118–145): J. Dik F. Habbema, Rene Eijkemans, Pieta Krijnen and J. Andre KnottnerusChapter 8 Multivariable Analysis in Diagnostic Accuracy Studies: What are the Possibilities? (pages 146–166): Frank Buntinx, Bert Aertgeerts, Marc Aerts, Rudi Bruyninckx, J. Andre Knottnerus, Ann van den Bruel and Jef van den EndeChapter 9 Standards for Reporting on Diagnostic Accuracy Studies (pages 167–179): Patrick M. M. Bossuyt and Nynke SmidtChapter 10 Guidelines for Conducting Systematic Reviews of Studies Evaluating the Accuracy of Diagnostic Tests (pages 180–212): Frank Buntinx, Bert Aertgeerts and Petra MacaskillChapter 11 Producing and Using Clinical Prediction Rules (pages 213–236): Tom Fahey and Johan van der LeiChapter 12 Clinical Problem Solving and Diagnostic Decision Making: A Selective Review of the Cognitive Research Literature (pages 237–255): Alan Schwartz and Arthur S. ElsteinChapter 13 Improving Test Ordering and its Diagnostic Cost?Effectiveness in Clinical Practice—Bridging the Gap between Clinical Research and Routine Health Care (pages 256–272): Ron Winkens, Trudy van der Weijden, Hans Severens and Geert?Jan DinantChapter 14 Epilogue: Overview of Evaluation Strategy and Challenges (pages 273–284): J. Andre Knottnerus, Ann van den Bruel and Frank Buntinx

this Unique Book Presents A Framework For The Strategy And Methodology Of Diagnostic Research, In Relation To Its Relevance For Practice. Now In Its Second Edition the Evidence Base Of Clinical Diagnosis Has Been Fully Revised And Extended With New Chapters Covering The Stard Guidelines (standards For The Reporting Of Diagnostic Accuracy Studies) And The Multivariable Analysis Of Diagnostic Data.

with Contributions From Leading International Experts In Evidence-based Medicine, This Book Is An Indispensable Guide On How To Conduct And Interpret Studies In Clinical Diagnosis. It Will Serve As A Valuable Resource For All Investigators Who Want To Embark On Diagnostic Research And For Clinicians, Practitioners And Students Who Want To Learn More About Its Principles And The Relevant Methodological Options Available.

doody Review Services

reviewer:s Hope Gilbert, Phd(lockheed Martin)
description:this Book Outlines The Methodological Steps For Appropriate Diagnostic Clinical Research. It Is A Thorough Guide To The World Of Study Evaluation, Design, Analysis, And Implementation.
purpose:it Describes The Necessities For The Advancement Of Clinical Diagnostic Research. Given The Advances In Medical Technology/knowledge/practice, This Book Provides The Means For Clinical Diagnostic Research To Progress At The Same Rate.
audience:this Is An Excellent Resource For Medical Professionals In Various Specialties. Epidemiologists, Practitioners, And Graduate Students Will Be Well Served By This Book And Its Emphasis On Linking Clinical Research And Healthcare. The Authors Are Obvious Experts In The Field Of Primary Care Research, And The Contributors Are A Diverse Group.
features:this Is A Thorough Compilation Of Clinical Research Methods And Practices. One Of The Key Chapters Is Chapter 7, Which Is An Excellent Explanation Of Basic Data Analysis And Interpretation Of Findings. This Is An Excellent Overview Of Epidemiology, The Interpretation Of Primary Statistical Findings, And The Impact That They Have On Clinical Practice.
assessment:the Authors Note That A Primary Reason For This Second Edition Is To Expound Upon Methodologies. They Have Also Nicely Incorporated Clinical Diagnosis With Implementation Into Practice.

General introduction : evaluation of diagnostic procedures / J. André Knottnerus, Frank Buntinx, and Chris van Weel The architecture of diagnostic research / R. Brian Haynes and John You Assessment of the accuracy of diagnostic tests : the cross-sectional study / J. André Knottnerus and Jean W. Muris Diagnostic testing and prognosis : the randomised controlled trial in test evaluation research / Jeroen G. Lijmer and Patrick M.M. Bossuyt The diagnostic before : after study to assess clinical impact / J. André Knottnerus, Geert-Jan Dinant, Onno P. Van Schayck Designing studies to ensure that estimates of test accuracy will travel / Les M. Irwig ... [et al.] Analysis of data on the accuracy of diagnostic tests J. Dik ... [et al.] Multivariable analysis in diagnostic accuracy studies : what are the possibilities? / F. Buntinx ... [et al.] Standards of reporting on diagnostic accuracy studies / P. Bossuyt and Nynke Smidt Guidelines for conducting systematic reviews of studies evaluating the accuracy of diagnostic tests / Frank Buntinx, Bert Aertgeerts, and Petra Macaskill Producing and using clinical prediction rules / Tom Fahey and Johan Van der Lei Clinical problem solving and diagnostic decision making : a selective review of the cognitive research literature / Alan Schwartz and Arthur S. Elstein Improving test ordering and its diagnostic cost effectiveness in clinical practice : bridging the gap between clinical research and routine health care / Ron A.G. Winkens ... [et al.] Epilogue : overview of evaluation strategy and challenges / J. André Knottnerus, Ann van den Bruel, and Frank Buntinx. This book was first published by BMJ Books in 2002, and based on a popular series published in the British Medical Journal. At that time it was unique in addressing evidence-based issues in the field of clinical diagnosis, and was enthusiastically received by the clinical research community for its thorough and insightful analysis of research methods in diagnosis. The information on effectiveness of clinical diagnosis tools was even more diffuse and sparse than now, and so the book became a point of reference for evidence-based diagnosis. The main basis for the text was discussion of diagnostic research tools and what evidence was available for their efficacy. The first edition is now over 3 years old Since publication much more information has been made available, including more clinically relevant data for problem solving and ordering diagnostic tests. The evidence-based health care community has turned the spotlight on diagnosis and it has become one of the hot topics in ebm. A new, more clinically focused edition of this well established book is timely