The Encyclopedia of Mass Spectrometry : Volume 9: Historical Perspectives, Part A: The Development of Mass Spectrometry
معرفی کتاب «The Encyclopedia of Mass Spectrometry : Volume 9: Historical Perspectives, Part A: The Development of Mass Spectrometry» نوشتهٔ Keith A. Nier, Alfred L. Yergey, P. Jane Gale، منتشرشده توسط نشر Elsevier Science & Technology Books در سال 2003. این کتاب در 20 صفحه، فرمت pdf، زبان انگلیسی ارائه شده است.
volume 5: Elemental And Isotope Ratio Mass Spectrometry
this Volume Focuses On (1) The Plethora Of Mostly Atomic Ionization Techniques That Have Been Coupled To Ms For Elemental Analysis, The Measurement Of Isotope Ratios, And Even The Determination Of Inorganic Compounds And (2) The Precise Measurement Of Isotope Ratios Of Organic Elements As Small Gas Molecules By Isotope Ratio Mass Spectrometry (irms). Chapter 1 Contains A Description Of Inductively Coupled Plasma (icp) Ms, Its Requirements For Sample Preparation And Introduction. The Chapter Also Covers Argon Icp, Ion Extraction, Various Mass Analyzers, And The Numerous Application Areas Including Environmental, Geochemical, Biomedical, Nuclear, Semiconductor, And Speciation. Other Atomic Sources Include The Microwave Plasma, Which Can Be Used As Either An Atomic Ionization Source Or As A Soft Molecular Ionization Source, Flames, Spark Sources, And Glow Discharges, Including The Types Of Mass Spectrometers And Separation Approaches To Which Interfaces Can Be Made.
chapter 2 Discusses The Application Of Electrospray Ionization (ei) Ms, Also Described In Volume 6, To Inorganic Analysis. Secondary Ion And Neutral Ms (chapter 3) Can Be Used To Determine Trace Elements In Solids, Particularly On Their Surface, With High Spatial Resolution. Atmospheric Aerosols Can Also Be Studied Using Laser(s) For Desorption And Ionization Of Analytes In Solids (chapter 4). Thermal Ionization Ms, Where Sample Atoms Or Molecules Are Ionized As They Evaporate From The Surface Of A Hot Filament, Is The Focus Of Chapter 5. Special Applications Are In Chapter 6, Which Covers Accelerator Ms, And Chapter 7, Where Large Calutrons Can Be Contrasted To The Small Analyzers That Are Taken Aboard Spacecraft, For Example.
chapter 8 Focuses On Irms For Precise Isotope Ratio Measurements. The Highest Level Of Precision Can Only Be Accomplished Through Use Of A Mass Spectrometer Specifically Esigned For The Purpose Of Making Differential Measurements. A Key Advance Is Direct Conversion Of Organic Compounds Into Small Gas Molecules For Measurement, Leading To Important Uses Ranging From Geology To Biomedical Sciences.
• Reviews The Wide Range Of Ionization And Isotope Methods Used In Inorganic Mass Spectrometry Today
• Features Tutorials Describing The Key Principles And Instrumentation Relevant To Each Method
• Evaluates Practical Applications For The Analysis Of Environmental, Biological, Biomedical, Nutritional, Geological, Nuclear, Microelectronic And Extra-terrestrial Materials
• Includes More Than 3400 References, 100 Tables And 500 Figures Of Which More Than 200 Are In Color
Volume 2: Biological Applications Part A
The focus of Volume 2 is peptides and proteins. The organization emphasizes separation techniques, preparation protocols, and fundamentals of ionic gas-phase species of biological importance. This volume is divided into four sections: (1) experimental approaches and protocols, (2) sequence analysis, (3) other structural analyses, and (4) targeted applications.
The first section encompass separation procedures (e.g., 2-D gel electrophoresis), sample preparation (e.g., desalting and enzyme digestion), and instrumentation issues (e.g., high resolving power, molecular-weight determination, protein chips, and quantification). H/D exchange, analysis of membrane proteins, and bioinformatics are included.
The next section on sequencing covers high energy and low energy CAD, protein identification, fundamentals of peptide fragmentation, bottom-up and top-down strategies, chemical derivatization, and post-source decay with MALDI. A section on structure analysis includes primary structure determination and issues with studying quaternary structure, protein-protein and protein-ligand complexes, disulfide analysis, phosphopeptides and phosphoproteins, selenoproteins, nitrated proteins, metal ion binding, and oxidized proteins. Additional coverage of methods for studying the biophysics of proteins is provided in Volume 6. The last chapter, Targeted Applications, focuses on neuropeptides, clinical applications, enzyme kinetics, imaging, and single-cell analysis.
• Frontier Research on biological, biochemical, and biomedical applications of MS
• Focus on Peptides and Proteins
• Suitable for new graduate students entering the field
The focus of Volume 2 of the Encyclopedia of Mass Spectrometry is on peptides and proteins, separation techniques, preparation protocols, and the fundamental characteristics as ionic gas phase species that lie within the breadth of the field of mass spectrometry. This volume is divided into four sections; experimental approaches and protocols, sequence analysis, other structural analyses, and targeted applications. Frontier Research on biological, biochemical, and biomedical applications of MS
Volume 4: Organic And Organometallic Compounds Presents A Cross Section Of Applications In Organic And Organometallic Chemistry In Two Parts. Chapters 1 To 6 Are Devoted To The Fundamentals Whereas Chapters 7 And 8 Cover Applications To Organic And Organometallic Compounds, Either Available As Pure Compounds Or Present In Complex Mixtures. Chapter 1 Describes The Theory For Organic Mass Spectrometry, Building On And Complementing Material In Volume 1. The Themes For Chapter 2 Are The Structures And Properties Of Gas-phase Ions Of Conventional, Distonic, And Non-covalent Complexes. Chapter 3 Covers Methodology Used In Study Of Gas-phase Ions. Chapters 4 And 5 Turn To Mechanisms Of Both Unimolecular And Bimolecular Reactions Of Ions And Include Topics In Stereochemistry And Radical Chemistry. Chapter 6 Contains A Number Of Articles On The Formation And Reactivity Of Metal Ion Complexes And Organometallic Cations And Anions, Drawing Connections With Molecular Recognition, Catalysis And Organic Synthesis. Chapter 7 Deals With The Structure Determination Of Organic Compounds, Including Chiral Compounds And Natural Products. In Chapter 8 Are Contributions That Provide Illustrative Examples Of The Determination Of Organic Compounds Present At Low Levels In Complex Samples That Originate From Various Natural And Biological Sources. Included Is An Article On The Determination Of Explosives. Cross Section Of The Field Of Organic And Organometallic Ms Covers Fundamental Ion Chemistry As Well As Applications From Simple To Complicated Systems Suitable For New Graduate Students Entering The Field __Volume 9: Historical Perspectives,____Part A: The Development of Mass Spectrometry__ of __The Encyclopedia of Mass Spectrometry__ describes and analyzes the development of many aspects of Mass Spectrometry. Beginning with the earliest types of Mass Analyzers, __Historical Perspectives__ explores the development of many different forms of analytical processes and methods. The work follows various instruments and interfaces, to the current state of detectors and computerization. It traces the use of Mass Spectrometry across many different disciplines, including Organic Chemistry, Biochemistry, and Proteomics; Environmental Mass Spectrometry; Forensic Science; Imaging; Medical Monitoring and Diagnosis; Earth and Planetary Sciences; and Nuclear Science. Finally, the book covers the history of manufacturers and societies as well as the professionals who form the Mass Spectrometry community. Also available: __Volume 9: Historical Perspectives, Part B: Notable People in Mass Spectrometry__ briefly reviews the lives and works of many of the major people who carried out this development. * Preserves the history and development of Mass Spectrometry for use across scientific fields * Written and edited by Mass Spectrometry experts * Coordinates with __Volume 9: Historical Perspectives, Part B: Notable People in Mass Spectrometry__, a collection of short biographies on many of the major people who carried out this development Volume 9: Historical Perspectives, Part A: The Development of Mass Spectrometry of The Encyclopedia of Mass Spectrometry describes and analyzes the development of many aspects of Mass Spectrometry. Beginning with the earliest types of Mass Analyzers, Historical Perspectives explores the development of many different forms of analytical processes and methods. The work follows various instruments and interfaces, to the current state of detectors and computerization. It traces the use of Mass Spectrometry across many different disciplines, including Organic Chemistry, Biochemistry, and Proteomics; Environmental Mass Spectrometry; Forensic Science; Imaging; Medical Monitoring and Diagnosis; Earth and Planetary Sciences; and Nuclear Science.Finally, the book covers the history of manufacturers and societies as well as the professionals who form the Mass Spectrometry community. Also available: Volume 9: Historical Perspectives, Part B: Notable People in Mass Spectrometry briefly reviews the lives and works of many of the major people who carried out this development. Preserves the history and development of Mass Spectrometry for use across scientific fields Written and edited by Mass Spectrometry experts Coordinates with Volume 9: Historical Perspectives, Part B: Notable People in Mass Spectrometry, a collection of short biographies on many of the major people who carried out this development v.1. Theory and ion chemistry / volume editor: Peter B. Armentrout v.2. Biological applications. pt. A. Peptides and proteins / volume editors: Richard M. Caprioli, Michael L. Gross v.3. Biological applications. Pt. B: carbohydrates, nucelic acods and other biological compounds v.4. Fundamentals of and applicationsn to organic (and organometallic) compounds v.6. Molecular ionization