The Doc and the Duchess: The Life and Legacy of George H. A. Clowes (Philanthropic and Nonprofit Studies)

"George Henry Alexander Clowes was a pivotal figure in the development of the insulin program at the Eli Lilly Company. Through his leadership, scientists and clinicians at Lilly and the University of Toronto created a unique, international team to develop and purify insulin and take the production of this life-saving agent to an industrial scale. This biography, written by his grandson, presents his scientific achievements, and also takes note of his social and philanthropic contributions, which he shared with his wife, Edith. It tells the story of Clowes from his childhood in late Victorian England to his death at Woods Hole on Cape Cod in 1958. Educated in England and Germany, Clowes came to America to join a startup laboratory in Buffalo, where he conducted basic research on cancer and applied research on other disease-related problems. Assuming the position of head of research at Lilly, Clowes was at the center of one of the great discoveries that changed the course of medical history and offered new life to millions of individuals with diabetes and other metabolic disorders. Clowes was also instrumental in the development of other commercial pharmaceutical advances. Devoted to a number of philanthropic causes, Clowes and Edith contributed greatly to the cultural life of his adopted country, a contribution that continues to this day." -- Amazon An “informative and enlightening” biography of a scientist who helped bring insulin to the world, and went on to become a prominent philanthropist (The Franklin Daily Journal).George Henry Alexander Clowes was a pivotal figure in the development of the insulin program at the Eli Lilly Company. Through his leadership, scientists and clinicians at Lilly and the University of Toronto created a unique international team to develop and purify insulin and take the production of this life-saving agent to an industrial scale.This biography, written by his grandson, presents his scientific achievements, and also takes note of his social and philanthropic contributions, which he shared with his wife, Edith. It tells the story of Clowes from his childhood in late Victorian England to his death at Woods Hole on Cape Cod in 1958. Educated in England and Germany, Clowes came to America to join a startup laboratory in Buffalo, where he conducted basic research on cancer and applied research on other disease-related problems. Assuming the position of head of research at Lilly, Clowes was at the center of one of the great discoveries that changed the course of medical history and offered new life to millions of individuals with diabetes and other metabolic disorders. Clowes was also instrumental in the development of other commercial pharmaceutical advances. Devoted to a number of philanthropic causes, Clowes and Edith contributed greatly to the cultural life of his adopted country, a contribution that continues to this day. Cover......Page 1 Contents......Page 8 Foreword......Page 10 Foreword......Page 14 Acknowledgments......Page 16 Introduction: A Warm Embrace......Page 20 1 Growing Up in Victorian England......Page 28 2 The Search for a Cure of Cancer......Page 39 3 Edith Whitehill Hinkel......Page 50 4 Alec and Edith......Page 65 5 1914: The End of an Era......Page 73 6 In the Borderline Fields of Medicine......Page 82 7 Lilly and the Insulin Story......Page 90 8 From Small- to Large-Scale Production of Insulin......Page 105 9 Expansion of Research Programs......Page 125 10 Woods Hole, MBL, and the Pursuit of Cancer......Page 133 11 The Duchess, the Doc, and the Boys......Page 141 12 Alec and Edith: Indianapolis Benefactors......Page 159 13 A Legacy: In Others’ Eyes......Page 173 Appendix 1: Publications of George Henry Alexander Clowes......Page 180 Appendix 2: Chronology of Ancestry......Page 192 Notes......Page 194 Bibliography......Page 206 B......Page 222 C......Page 223 D......Page 224 H......Page 225 J......Page 226 M......Page 227 S......Page 228 W......Page 229 Z......Page 230