The diversity of gastric carcinoma : pathogenesis, diagnosis, and therapy

Japan has long been a leader of research into the carcinogenesis, pathology, diagnosis, and treatment of gastric carcinoma, which is still the second leading cause of cancer death worldwide. Distinguished experts in the field collaborated in creating this groundbreaking work, providing a comprehensive view of gastric cancer. This book encourages further development of gastric cancer research and its clinical application. Topics include all aspects of gastric carcinoma, such as the history of clinical and experimental gastric cancer research; updated issues of molecular and pathological research on gastric carcinogenesis; multidisciplinary methods in diagnosis, treatment, and chemotherapy; and perspectives in minimally invasive surgery. Color figures of histological specimens and other clinical features assist readers in readily understanding the textual descriptions, making this volume a valuable source for clinicians and researchers alike. Contents......Page 7 Foreword......Page 5 Preface......Page 6 Contributors......Page 10 Part 1 History of Gastric Carcinoma Research......Page 17 History of Gastric Carcinoma Research in Japan: Basic Aspects......Page 18 Historical Review of Research and Treatment of Gastric Cancer in Japan: Clinical Aspect......Page 44 Part 2 Recent Advances in Molecular Carcinogenesis in Gastric Carcinoma......Page 63 Recent Advances in Molecular Pathobiology of Gastric Carcinoma......Page 64 Part 3 Pathogenesis and Pathology......Page 85 Helicobacter pylori and Gastric Carcinoma......Page 86 Fundic Mucosal Change Associated with Oxyntic Atrophy......Page 98 DNA Methylation and Gastric Carcinoma......Page 108 Distinction of High-Grade Intraepithelial Neoplasia and Tubular Gastric Adenocarcinoma......Page 120 Histological Diversity of Early Gastric Carcinoma......Page 128 Epstein–Barr Virus-Associated Gastric Carcinoma......Page 137 Hepatoid Adenocarcinoma of the Stomach: Biological Significance of Hepatic Transdifferentiation in Adenocarcinoma Cells......Page 148 Oncocytic Adenocarcinoma of the Stomach: Comparison with Parietal Cell Carcinoma......Page 159 Gastric Carcinoma in the Elderly......Page 167 Adenocarcinoma with Gastric Mucin Phenotype......Page 176 Part 4 Clinical Diagnosis......Page 189 Endoscopic Diagnosis of Gastric Carcinoma......Page 190 Ultrasonic Diagnosis of Gastric Cancer......Page 208 Recent Advances in Radiology for the Diagnosis of Gastric Carcinoma......Page 225 Part 5 Therapy for Gastric Carcinoma......Page 237 The Gastric Cancer Treatment Guideline......Page 238 Endoscopic Resection for Early Gastric Cancer......Page 245 Current Treatment Strategies for Early Gastric Cancer......Page 255 Surgery for Advanced Gastric Cancer......Page 273 Laparoscopic Gastrectomy......Page 289 Chemotherapy for Advanced Unresectable Gastric Cancer......Page 301 Adjuvant or Neoadjuvant Chemotherapy Against Advanced Gastric Carcinoma......Page 312 Part 6 Recent Topics in Gastric Carcinoma Research......Page 327 Micrometastasis of Gastric Cancer......Page 328 Sentinel Node Navigation Surgery: Application to Minimally Invasive and Function-Preserving Surgery for Early Gastric Cancer......Page 338 D......Page 348 G......Page 349 M......Page 350 S......Page 351 Y......Page 352 History Of Gastric Carcinoma Research: History Of Gastric Carcionoma Research In Japan / By M. Tatematsu, T. Tsukamoto, T. Mizoshita. Historical Review Of Research And Treatment Of Gastric Cancer In Japan / By T. Nakajima. Recent Advances In Molecular Carcinogenesis In Gastric Carcinoma: Recent Advances In Molecular Pathobiology Of Gastric Carcinoma / By W. Yasui And Others Pathogenesis And Pathology: Helicobacter Pylori And Gastric Carcinoma / N. Shimizu, M. Tatematsu, M. Kaminishi. Fundic Mucosal Change Associated With Oxyntic Atrophy / By H. Yamaguchi And Others Dna Methylation And Gastric Carcinoma / By A. Kaneda. Distinction Of High-grade Intraepithelial Neoplasia And Tubular Gastric Adenocarcinoma / By M. Vieth M. Stolte. Histological Diversity Of Early Gastric Carcinoma / By Y. Ohkura. Epstein-barr Virus-associated Gastric Carcinoma / By J.-m. Chong, H. Uozaki, M. Fukayama. Hepatoid Adenocarcinoma Of The Stomach / By H.^ Ishikura And Others Oncocytic Adenocarcinoma Of The Stomach / By K. Takubo T. Arai. Gastric Carcinoma In The Elderly / By T. Arai. Adenocarcinoma With Gastric Mucin Phenotype / By H. Yokozaki And Others Clinical Diagnosis: Endoscopic Diagnosis Of Gastric Carcinoma / K. Iwakiri, Y. Hayashi, C. Sakamoto. Ultrasonic Diagnosis Of Gastric Cancer / By H. Yasuda And Others Recent Advances In Radiology For The Diagnosis Of Gastric Carcinoma / By G. Iinuma And Others Therapy For Gastric Carcinoma: The Gastric Cancer Treatment Guideline / By M. Sasako. Endoscopic Resection For Early Gastric Cancer / By M. Fujishiro. Current Treatment Strategies For Early Gastric Cancer / By S. Shimoyama, M. Kaminishi. Surgery For Advanced Gastric Cancer / By K. Mafune. Laparoscopic Gastrectomy / By S. Kitano, T. Etoh, N. Shiraishi. Chemotherapy For Advanced Unresectable Gastric Cancer / By A. Ohtsu. Adjuvant Or Neoadjuvant Chemotherapy Against Advanced Gastric Carcinoma / By K. Omura.^ Recent Topics In Gastric Carcinoma Research: Micrometastasis Of Gastric Cancer / By S. Natsugoe And Others Sentinel Node Navigation Surgery / Y. Otani And Others. M. Kaminishi, K. Takubo, K. Mafune (eds.). Includes Bibliographical References And Index. • Japan is a leader in screening for and treating gastric cancer - this title first publishes Japan's newest research in English • Contributors are internationally recognized specialists with publications on gastrointestinal cancers in many high ranking medical journals from Europe and the USA • Michio Kaminishi was president of the 3rd International Conference of the ISGC "This book encourages further development of gastric cancer research and its clinical application. Color figures of histological specimens and other clinical features assist readers in readily understanding the textual descriptions, making this volume a valuable source for clinicians and researchers alike."--BOOK JACKET Human gastric cancers histologically present with various morphological structures, which is one of the most characteristic features compared with other digestive apparatus carcinomas.