The Cerebral Cortex in Neurodegenerative and Neuropsychiatric Disorders : Experimental Approaches to Clinical Issues

__The Cerebral Cortex in Neurodegenerative and Neuropsychiatric Disorders: Experimental Approaches to Clinical Issues__ focuses on how pre-clinical investigations are addressing the clinical issues surrounding the involvement of the cerebral cortex in selected conditions of the nervous system, including Alzheimer’s Disease, Parkinson’s, addiction, and cardiovascular dysregulation. Each chapter is written by an expert in his/her field who provides a comprehensive review of the clinical manifestations of cortical involvement and experimental techniques currently available to tackle cortical issues in disease. Thus, this present title provides a link between cortical clinical problems and investigational approaches to help foster future research with high translational value. * Offers a comprehensive overview on the best available in vivo and in vitro models to study cortical involvement * Presents models and specific techniques that help to guide investigators in their choices on how to address research questions experimentally * Provides expert commentary and a perspective on future trends at the end of each chapter * Addresses translational advances and promising therapeutic options * Includes references to key articles for additional detailed study

The Cerebral Cortex in Neurodegenerative and Neuropsychiatric Disorders: Experimental Approaches to Clinical Issues focuses on how pre-clinical investigations are addressing the clinical issues surrounding the involvement of the cerebral cortex in selected conditions of the nervous system, including Alzheimer’s Disease, Parkinson’s, addiction, and cardiovascular dysregulation.

Each chapter is written by an expert in his/her field who provides a comprehensive review of the clinical manifestations of cortical involvement and experimental techniques currently available to tackle cortical issues in disease. Thus, this present title provides a link between cortical clinical problems and investigational approaches to help foster future research with high translational value.

• Offers a comprehensive overview on the best available in vivo and in vitro models to study cortical involvement
• Presents models and specific techniques that help to guide investigators in their choices on how to address research questions experimentally
• Provides expert commentary and a perspective on future trends at the end of each chapter
• Addresses translational advances and promising therapeutic options
• Includes references to key articles for additional detailed study

Content: Front Matter,Copyright,List of Contributors,Foreword,IntroductionEntitled to full textPart I: Introductory ChaptersChapter 1 - Anatomy of the Cerebral Cortex, Pages 3-36, K.S. Rockland Chapter 2 - Cortical Plasticity in Response to Injury and Disease, Pages 37-56, N. Weishaupt Chapter 3 - Imaging Approaches to Cerebral Cortex Pathology, Pages 57-80, R. Bartha, T.-Y. Lee Chapter 4 - Alzheimer’s Disease, Pages 83-118, J.H.K. Tam, S.H. Pasternak Chapter 5 - Vascular Dementia, Pages 119-139, D.G. Munoz, N. Weishaupt Chapter 6 - Frontotemporal Dementia, Pages 141-175, A.E. Arrant, E.D. Roberson Chapter 7 - Parkinson’s Disease and the Cerebral Cortex, Pages 177-193, D.F. Cechetto, M. Jog Chapter 8 - Huntington Disease, Pages 195-221, E.H. Kim, N. Mehrabi, L.J. Tippett, H.J. Waldvogel, R.L.M. Faull Chapter 9 - Cortical Manifestations in Amyotrophic Lateral Sclerosis, Pages 223-242, A.J. Moszczynski, M.J. Strong Chapter 10 - Cortical Involvement in Multiple Sclerosis, Pages 243-273, P. Bannerman Chapter 11 - Prefrontal Cortical Abnormalities in Cognitive Deficits of Schizophrenia, Pages 277-287, N. Rajakumar Chapter 12 - Role of the Prefrontal Cortex in Addictive Disorders, Pages 289-309, J. Renard, L. Rosen, W.J. Rushlow, S.R. Laviolette List of Acronyms and Abbreviations, Pages 311-314 Index, Pages 315-320 Editors, David F. Cechetto, Nina Weishaupt. Includes Bibliographical References And Index. Mode Of Access: World Wide Web.