The Biology of Neuropeptide Y and Related Peptides (Contemporary Neuroscience)

Leading experts critically summarize the state of knowledge concerning the molecular, anatomical, physiological, and behavioral aspects of NPY and its congeners. Each article provides a comprehensive and in-depth survey, an overview of the role of NPY in the discipline covered, a discussion of the likely future direction that the field will take, and an up-to-date bibliography. Chapters include a treatment of the evolution of the PP family of genes, the structure of the NPY gene, and the distribution of NPY on the cardiovascular system, actions of NPY on the electrophysiological properties of nerve cells, and the effects of NPY on feeding and behavior. The chapters are written in an accessible style and serve both as an introduction to the field and as an extensive and detailed treatment of the current state of knowledge. Evolution Of The Neuropeptide Y Family Of Peptides / Dan Larhammar, Charlotte Soderberg And Anders G. Blomqvist -- Structure And Expression Of The Neuropeptide Y Gene / Janet M. Allen And Domingo Balbi -- Organization Of Neuropeptide Y Neurons In The Mammalian Central Nervous System / Stewart H.c. Hendry -- Pp, Pyy And Npy: Occurrence And Distribution In The Periphery / F. Sundler [and Others] -- Characterization Of Receptor Types For Neuropeptide Y And Related Peptides / Lars Grundemar, Soren P. Sheikh And Claes Wahlestedt -- Actions Of Neuropeptide Y On The Electrophysiological Properties Of Nerve Cells / David Bleakman, Richard J. Miller And William F. Colmers -- Role Of Npy And Related Peptides In The Control Of Gastrointestinal Function / Helen M. Cox -- Origin And Actions Of Neuropeptide Y In The Cardiovascular System / Zofia Zukowska-grojec And Claes Wahlestedt -- Central Cardiovascular Actions Of Neuropeptide Y / Moira A. Mcauley, Xiaoli Chen And Thomas C. Westfall -- Neuropeptide Y Actions On Reproductive And Endocrine Functions / John K. Mcdonald And James I. Koenig. (cont) Neuropeptide Y In Multiple Hypothalamic Sites Controls Eating Behavior, Endocrine, And Autonomic Systems For Body Energy Balance / B. Glenn Stanley -- Neuropeptide Y In Relation To Behavior And Psychiatric Disorders: Some Animal And Clinical Observations / Markus Heilig. Edited By William F. Colmers And Claes Wahlestedt. Includes Bibliographical References And Index. Front Matter....Pages i-xvi Evolution of the Neuropeptide Y Family of Peptides....Pages 1-41 Structure and Expression of the Neuropeptide Y Gene....Pages 43-64 Organization of Neuropeptide Y Neurons in the Mammalian Central Nervous System....Pages 65-156 PP, PYY, and NPY....Pages 157-196 Characterization of Receptor Types for Neuropeptide Y and Related Peptides....Pages 197-239 Actions of Neuropeptide Y on the Electrophysiological Properties of Nerve Cells....Pages 241-272 The Role of NPY and Related Peptides in the Control of Gastrointestinal Function....Pages 273-313 Origin and Actions of Neuropeptide Y in the Cardiovascular System....Pages 315-388 Central Cardiovascular Actions of Neuropeptide Y....Pages 389-418 Neuropeptide Y Actions on Reproductive and Endocrine Functions....Pages 419-456 Neuropeptide Y in Multiple Hypothalamic Sites Controls Eating Behavior, Endocrine, and Autonomic Systems for Body Energy Balance....Pages 457-509 Neuropeptide Y in Relation to Behavior and Psychiatric Disorders....Pages 511-554 Back Matter....Pages 555-564 Twelve review articles by leading experts critically summarize the state of knowledge concerning molecular, anatomical, physiological and behavioural aspects of NPY and its congeners.