[(The Antibodies: Vol. 7)] [Author: Donald J. Capra] published on (October, 2002) [ISBN : 9780415284660]

Annotation From diagnostic tools to therapy against cancer, infections and autoimmune diseases, antibodies serve many purposes, yet our knowledge of them is still incomplete. The Antibodies: Volume 7 continues with a comprehensive review of topics of contemporary interest including major breakthroughs such as the advent of monoclonal antibodies and the development of new techniques of antibody engineering that have kept antibodies at the forefront of immunology and medical science. While examining the ground-breaking discoveries of the last two decades this book also revisits more traditional aspects of the field to give an holistic approach to this increasingly popular area of medicine Book Cover......Page 1 Title......Page 4 Contents......Page 5 Series Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .......Page 8 Preface: Volume 7 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .......Page 10 List of Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .......Page 12 Positive Selection of B-Cell Repertoire, Idiotype Networks and Immunological Memory......Page 14 The Utility of Immunoglobulin Fusions in DNA Immunization......Page 42 Constraints on the Hydropathicity and Sequence Composition of HCDR3 are Conserved Across Evolution......Page 56 Molecular Aspects of Anti-Polysaccharide Antibody Responses......Page 82 Molecular Farming Antibodies in Plants: From Antibody Engineering to Antibody Production......Page 124 Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .......Page 178 Index to Volumes 1 6 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .......Page 184 Contents of Previous Volumes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .......Page 222 Bioscience & Clinical Medicine Book Cover 1 Title 4 Contents 5 Series Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 Preface: Volume 7 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 List of Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 Positive Selection of B-Cell Repertoire, Idiotype Networks and Immunological Memory 14 The Utility of Immunoglobulin Fusions in DNA Immunization 42 Constraints on the Hydropathicity and Sequence Composition of HCDR3 are Conserved Across Evolution 56 Molecular Aspects of Anti-Polysaccharide Antibody Responses 82 Molecular Farming Antibodies in Plants: From Antibody Engineering to Antibody Production 124 Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 178 Index to Volumes 1 6 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184 Contents of Previous Volumes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 222 A comprehensive review of topics of contemporary interest for specialists in B-cell immunology, this volume investigates such topics as aspects of antibody-protein antigen interactions; immunoglobin genes; genome organization and expression; and intrabodies. Examining the ground-breaking discoveries of the past two decades and revisiting the more traditional aspects of the field, this book takes an holistic approach to this exciting and increasingly popular area of medicine Antigen recognition proteins of the immune system, immunoglobulin (Ig) and T-cell receptors (TCR) are created by a complex DNA recombination pathway in developing lymphocytes. This work aims to provide the scientific community with a platform for comprehensive review of topics of contemporary interest for specialists in the area of antibodies.