Textbook of Diabetes and Pregnancy 2nd Edition (Series in Maternal-Fetal Medicine)

Babies of women with diabetes are nearly five times more likely to be stillborn; are almost three times more likely to die in the first three months; and twice as many are born with major congenital malformations. The incidence is high—somewhere between 3 and 7 per cent of all pregnant women in the USA have diabetes—and rising; the condition is often complicated by other risk-factors such as obesity and heart disease. This major book gives a comprehensive review of the epidemiology, science and clinical management of gestation diabetes. Fully updated and revised, it contains new chapters on: Fetal growth in normal and diabetic pregnancies Genetics Congenital anomalies Exercise Pharmacological management Insulin pump therapy Hypoglycemia The role of ultrasound for timing of delivery Thyroid and pregnancy Fetal origins of adult disease Metabolic syndrome and diabetes following gestational diabetes mellitus Psychological and social aspects The book provides a comprehensive, authoritative, international view of these difficult pregnancies and will be invaluable to maternal-fetal medicine specialists, diabetologists, neonatologists, and basic scientists working in the field. cover......Page p0001.djvu SERIES IN MATERNAL–FETAL MEDICINE......Page p0003.djvu Textbook of Diabetes and Pregnancy, Second Edition......Page p0004.djvu Contents......Page p0008.djvu Contributors......Page p0012.djvu Foreword......Page p0016.djvu Preface......Page p0018.djvu Abbreviations......Page p0020.djvu 1 History of diabetic pregnancy......Page p0024.djvu 2 The Priscilla White legacy......Page p0032.djvu 3 The Pedersen legacy......Page p0038.djvu 4 The Freinkel legacy......Page p0042.djvu 5 Metabolism in normal pregnancy......Page p0048.djvu 6 Intermediary metabolism in pregnancies complicated by gestational diabetes......Page p0058.djvu 7 Histopathology of placenta......Page p0064.djvu 8 The placenta in diabetic pregnancy: Placental transfer of nutrients......Page p0070.djvu 9 Nutrient delivery and metabolism in the fetus......Page p0080.djvu 10 Pathogenesis of gestational diabetes mellitus......Page p0094.djvu 11 Fetal growth in normal and diabetic pregnancies......Page p0102.djvu 12 Pregnancy in diabetic animals......Page p0109.djvu 13 Immunology of gestational diabetes mellitus......Page p0123.djvu 14 Gestational diabetes: The consequences of not-treating......Page p0130.djvu 15 Epidemiology of gestational diabetes mellitus......Page p0141.djvu 16 Gestational diabetes in Latin America......Page p0155.djvu 17 Diabetes and pregnancy in advancing nations: India......Page p0158.djvu 18 Diabetes and pregnancy in New Zealand......Page p0165.djvu 19 Gestational diabetes in China......Page p0170.djvu 20 Diabetes and pregnancy in Japan......Page p0173.djvu 21 Detection and diagnostic strategies for gestational diabetes mellitus......Page p0179.djvu 22 Diabetic embryopathy in the pre-implantation embryo......Page p0188.djvu 23 Congenital malformations in diabetic pregnancy: Prevalence and types......Page p0196.djvu 24 Post-implantation diabetic embryopathy......Page p0201.djvu 25 Management of gestational diabetes mellitus......Page p0211.djvu 26 Medical nutritional therapy for gestational diabetes mellitus......Page p0219.djvu 27 Insulin therapy in pregnancy......Page p0228.djvu 28 Oral anti-diabetic agents in pregnancy: Their time has come......Page p0240.djvu 29 Continuous glucose monitoring during pregnancies complicated by diabetes mellitus......Page p0251.djvu 30 Insulin pumps in pregnancy......Page p0256.djvu 31 Artificial pancreas and pregnancy: Closing the loop......Page p0264.djvu 32 Hypoglycemia in diabetic pregnancy......Page p0269.djvu 33 Sonography in diabetic pregnancies......Page p0276.djvu 34 Diabetes in Pregnancy: Is Doppler useful?......Page p0282.djvu 35 Fetal lung maturity......Page p0288.djvu 36 Monitoring in labor......Page p0299.djvu 37 Timing and mode of delivery......Page p0306.djvu 38 Prevention of fetal macrosomia......Page p0314.djvu 39 Timing and delivery of the macrosomic infant: Induction versus conservative management......Page p0320.djvu 40 Management of the macrosomic fetus......Page p0327.djvu 41 Hypertensive disorders and diabetic pregnancy......Page p0331.djvu 42 Diabetic retinopathy......Page p0341.djvu 43 Diabetic vascular complications in pregnancy: Nephropathy......Page p0353.djvu 44 Diabetic ketoacidosis in pregnancy......Page p0356.djvu 45 Gestational diabetes in multiple pregnancies......Page p0361.djvu 46 Thyroid diseases in pregnancy......Page p0366.djvu 47 Short-term implications: The neonate......Page p0375.djvu 48 Long-term implications: Child and adult......Page p0385.djvu 49 Growth and neuro-developmentof children born to diabetic mothers and to mothers with gestational diabetes......Page p0394.djvu 50 Diabetes mellitus and the metabolic syndrome after gestational diabetes......Page p0402.djvu 51 Evidence-based medicine and diabetic pregnancy......Page p0408.djvu 52 Cost analysis of diabetes and pregnancy......Page p0415.djvu 53 Quality of care for the woman with diabetes in pregnancy......Page p0422.djvu 54 Ethical issues in management of pregnancy complicated by diabetes......Page p0432.djvu 55 Legal aspects of diabetic pregnancy......Page p0438.djvu 56 Diabetologic education in pregnancy......Page p0447.djvu 57 Databases: A tool for quality management of diabetic pregnancies......Page p0454.djvu 58 Introduction to technological disease-management tools and eHealth networks: The future of better care delivery in diabetes and pregnancy......Page p0462.djvu 59 Optimal contraception for the diabetic woman......Page p0476.djvu 60 Hormone replacement therapy and diabetes......Page p0481.djvu 61 The genetics of diabetic pregnancy......Page p0489.djvu 62 The integration of compliance, communication and culture to enhance health care delivery......Page p0498.djvu 63 Diabetes and infertility......Page p0505.djvu 64 Early pregnancy loss and perinatal mortality......Page p0516.djvu Index......Page p0526.djvu Back......Page p0538.djvu Babies Of Women With Diabetes Are Nearly Five Times More Likely To Be Stillborn; Are Almost Three Times More Likely To Die In The First Three Months; And Twice As Many Are Born With Major Congenital Malformations. The Incidence Is High--somewhere Between 3 And 7 Per Cent Of All Pregnant Women In The Usa Have Diabetes--and Rising; The Condition Is Often Complicated By Other Risk-factors Such As Obesity And Heart Disease. This Book Gives A Comprehensive Review Of The Epidemiology, Science And Clinical Management Of Gestation Diabetes. The Book Provides A Comprehensive, Authoritative, International View Of These Difficult Pregnancies And Will Be Invaluable To Maternal-fetal Medicine Specialists, Diabetologists, Neonatologists, And Basic Scientists Working In The Field. History Of Diabetic Pregnancy -- The Priscilla White Legacy -- The Pederson Legacy -- The Freinkel Legacy -- Metabolism In Normal Pregnancy -- Intermediary Metabolism In Pregnancies Complicated By Gestational Diabetes -- Histopathology Of Placenta -- The Placenta In Diabetic Pregnancy: Placental Transfer Of Nutrients -- Nutrient Delivery And Metabolism In The Fetus -- Pathogenesis Of Gestational Diabetes Mellitus -- Fetal Growth In Normal And Diabetic Pregnancies -- Pregnancy In Diabetic Animals -- Immunology Of Gestational Diabetes Mellitus -- Gestational Diabetes: The Consequences Of Not-treating -- Epidemiology Of Gestational Diabetes Mellitus -- Gestational Diabetes In Latin America -- Diabetes And Pregnancy In Advancing Nations: India -- Diabetes And Pregnancy In New Zealand -- Gestational Diabetes In China -- Diabetes And Pregnancy In Japan -- Detection And Diagnostic Strategies For Gestational Diabetes Mellitus -- Diabetic Embryopathy In The Pre-implantation Embryo -- Congenital Malformations In Diabetic Pregnancy: Prevalence And Types -- Post-implantation Diabetic Embryopathy -- Management Of Gestational Diabetes Mellitus -- Medical Nutritional Therapy For Gestational Diabetes Mellitus -- Insulin Therapy In Pregnancy -- Oral Anti-diabetic Agents In Pregnancy: Their Time Has Come -- Continuous Glucose Monitoring During Pregnancies Complicated By Diabetes Mellitus -- Insulin Pumps In Pregnancy -- Artificial Pancreas And Pregnancy: Closing The Loop -- Hypoglycemia In Diabetic Pregnancy -- Sonography In Diabetic Pregnancies -- Diabetes In Pregnancy: Is Dopoler Useful? -- Fetal Lung Maturity -- Monitoring In Labor -- Timing And Mode Of Delivery -- Prevention Of Fetal Macrosomia -- Timing And Delivery Of The Macrosomic Infant: Induction Versus Conservative Management -- Management Of The Macrosomic Fetus -- Hypertensive Disorders And Diabetic Pregnancy -- Diabetic Retinopathy -- Diabetic Vascular Complications In Pregnancy: Nephropathy -- Diabetic Ketoacidosis In Pregnancy -- Gestational Diabetes In Multiple Pregnancies -- Thyroid Diseases In Pregnancy -- Short-term Implications: The Neonate -- Long-term Implications: Child And Adult -- Growth And Neurodevelopment Of Children Born To Diabetic Mothers And To Mothers With Gestational Diabetes -- Diabetes Mellitus And Metabolic Syndrome After Gestational Diabetes -- Evidence-based Medicine And Diabetic Pregnancy -- Cost Analysis Of Diabetes And Pregnancy -- Quality Of Care For The Woman With Diabetes In Pregnancy -- Ethical Issues In Management Of Pregnancy Complicated By Diabetes -- Legal Aspects Of Diabetic Pregnancy -- Diabetologic Education In Pregnancy -- Databases: A Tool For Quality Management Of Diabetic Pregnancies -- Introduction To Technological Disease-management Tools And Ehealth Networks: The Future Of Better Care Delivery In Diabetes And Pregnancy -- Optimal Contraception For The Diabetic Woman -- Hormone Replacement Therapy And Diabetes -- The Genetics Of Diabetic Pregnancy -- The Integration Of Compliance, Communication And Culture To Enhance Health Care Delivery -- Diabetes And Infertility -- Early Pregnancy Loss And Perinatal Mortality. Edited By Moshe Hod ... [et Al.]. Includes Bibliographical References And Index.