Sulfur in proteins proceedings of a Symposium held at Falmouth, Massachusetts, May, 1958

Sulfur in Proteins is a collection of papers presented at the 1958 Symposium on Sulfur in Proteins, held in Falmouth, Massachusetts. The symposium primary aims to explore the varied and unusual roles of –S–S– and –SH groups in proteins. This book is organized into eight chapters that cover a wide variety of proteins, including serum, iron, copper, and muscle proteins, as well as enzymes and viruses. The opening chapter describes the various protein reactions involving sulfur, emphasizing the chemical modification of thiol and disulfide groups. Considerable chapters are devoted to the chemical properties, biogenesis, reactivity, and oxygenation of specific proteins. A chapter highlights some aspects of protein structure in relation to the role of –S–S– and –SH groups in enzymic catalysis. This chapter also describes the properties of sulfhydryl groups in yeast alcohol dehydrogenase. The final chapters examine the role of sulfur groups in several virus proteins and in cell division. This work will be of great value to protein scientists and researchers. Content: Front Matter , Page iii Copyright , Page iv PARTICIPANTS , Pages v-vi INTRODUCTION , Page vii I. 1 - CHEMICAL MODIFICATION OF THIOL AND DISULFIDE GROUPS IN PROTEINS AND PEPTIDES , Pages 3-14 , J.M. Swan I. 2 - THE INTRODUCTION OF NEW SULFHYDRYL GROUPS AND DISULFIDE BONDS INTO PROTEINS , Pages 15-24 , Reinhold Benesch, Ruth E. Benesch I. 3 - DISULFIDE BONDS IN PROTEINS , Pages 25-31 , James E. Turner, Margaret B. Kennedy, Felix Haurowitz I. 4 - THE VARYING REACTIVITY OF THE CYSTINE OF WOOL , Pages 33-49 , H. Lindley I. 5 - A HIGH-SULFUR PROTEIN FROM WOOL , Pages 51-54 , J.M. Gillespie I. 6 - THE DECOMPOSITION OF KERATIN BY MICROORGANISMS , Pages 55-57 , Joseph J. Noval, Walter J. Nickerson I. 7 - THE SUPERCONTRACTION OF KERATIN FIBERS BY LITHIUM BROMIDE , Pages 59-71 , Alfred E. Brown, Lawrence G. Beauregard II. 1 - SOME CHEMICAL PROPERTIES OF THE SULFHYDRYL GROUP IN BOVINE PLASMA ALBUMIN , Pages 75-92 , Elwood V. Jensen II. 2 - RELATIVE PROBABILITIES OF ISOMERS IN CYSTINE-CONTAINING RANDOMLY COILED POLYPEPTIDES , Pages 93-108 , Walter Kauzmann II. 3 - BIOGENESIS OF PROTEIN FIBERS: THE CLOTTING OF BLOOD PLASMA , Pages 109-124 , L. Lorand, Ann Jacobsen, Lily E. Fuchs III. 1 - THE ROLE OF SULFUR IN SOME METAL-PROTEINS , Pages 127-140 , Irving M. Klotz, Themis A. Klotz III. 2 - THE ROLE OF SULFUR IN CYTOCHROME c , Pages 141-151 , H. Tuppy III. 3 - THE CYSTINE/CYSTEINE CONTENT OF HEMOGLOBINS , Pages 153-172 , T.H.J. Huisman III. 4 - SULFHYDRYL GROUPS AND THE OXYGENATION OF HEMOGLOBIN , Pages 173-187 , Austen Riggs III. 5 - RELATION OF IRON TO SULFHYDRYL GROUPS IN FERRITIN , Pages 189-196 , Abraham Mazur, Saul Green IV. 1 - SOME ASPECTS OF PROTEIN STRUCTURE IN RELATION TO THE ROLE OF —SH AND —S—S— GROUPS IN ENZYMIC CATALYSIS , Pages 199-213 , P.D. Boyer, A.R. Schulz IV. 2 - MECHANISM OF ACTION OF ALCOHOL DEHYDROGENASES FROM YEAST AND LIVER AND β-GALACTOSIDASE OF E. COLI , Pages 215-243 , Kurt Wallenfels, Horst Sund, Marie Luise Zarnitz, Om Prakash Malhotra, Jürgen Fischer IV. 3 - DETERMINATION AND PROPERTIES OF SULFHYDRYL GROUPS IN YEAST ALCOHOL DEHYDROGENASE , Pages 245-265 , Frederic L. Hoch, Bert L. Vallee IV. 4 - FLUOROMETRIC ANALYSIS OF COENZYME BINDING AND THIOL INTERACTIONS ON GLYCERALDEHYDE-3-PHOSPHATE AND LACTIC DEHYDROGENASES , Pages 267-278 , Sidney F. Velick IV. 5 - ON THE ORDER OF DISULFIDE BOND REDUCTION IN RIBONUCLEASE , Pages 279-288 , F.H. White Jr., C.B. Anfinsen V. 1 - CYSTEINE AND CYSTINE CONTENT OF MUSCLE PROTEIN FRACTIONS , Pages 291-295 , Andrew G. Szent-Györgyi, R.E. Benesch, R. Benesch V. 2 - THE ROLE OF SH GROUPS IN THE INTERACTION OF MYOSIN WITH PHOSPHATE COMPOUNDS AND WITH ACTIN , Pages 297-315 , J. Gergely, A. Martonosi, M.A. Gouvea V. 3 - STUDIES ON THE FUNCTIONAL SULFHYDRYL GROUPS OF MYOSIN AND ACTIN , Pages 317-336 , Michael Bárány VI. 1 - THE MASKED —SH GROUP IN TOBACCO MOSAIC VIRUS PROTEIN , Pages 339-346 , H. Fraenkel-Conrat VI. 2 - STRUCTURE AND FUNCTION IN T2 BACTERIOPHAGE , Pages 347-364 , Lloyd M. Kozloff VII. 1 - THE ROLE OF THIOL GROUPS IN THE STRUCTURE AND FUNCTION OF THE MITOTIC APPARATUS , Pages 367-389 , Daniel Mazia VII. 2 - MULTIPLE FUNCTIONS OF SULFUR IN MITOSIS , Pages 391-408 , Herbert Stern VII. 3 - FUNCTION OF PROTEIN DISULFIDE REDUCTASE IN CELLULAR DIVISION OF YEASTS , Pages 409-424 , Walter J. Nickerson, G. Falcone VIII - SUMMARY , Pages 427-442 , J.T. Edsall AUTHOR INDEX , Pages 443-452 SUBJECT INDEX , Pages 453-469