Stroke MRI

Stroke MRI is a new imaging tool providing detailed information of the pathophysiological aspects of cerebral ischemia. This book with CD-ROM includes a case collection of 25 hyperacute stroke patients, all imaged within six hours of stroke onset with a complete stroke MRI protocol. Stroke MRI and the established clinical methods are compared and recent results from single and multicenter trials are presented to demonstrate the advantages of MRI for stroke patients. The CD-ROM contains diffusion-, T2-, T2\*-perfusion-weighted images and MR angiography. Each case offers to answer the relevant questions concerning vessel status and lesion size as well as presence or absence of a "tissue at risk" with a self assessment mode and the experts’ therapeutic decision. The CD and the book are complementary to avoid redundancy as far as possible. They will be useful to both the experienced researcher using MRI and the clinician or researcher with no previous knowledge of the technology. Front Matter....Pages I-IX Introduction....Pages 1-2 CT as the Current Standard in Stroke Imaging....Pages 3-6 Stroke Scales....Pages 7-11 Conventional MRI, Diffusion-weighted MRI (DWI) and Apparent Diffusion Coefficient (ADC)....Pages 13-21 Perfusion-weighted MM (PWI)....Pages 23-29 The Penumbra and the Mismatch Concept....Pages 31-34 Stroke MRI and Intracranial Hemorrhage....Pages 35-44 Feasibility, Practicality and Logistics of a Multisequence Stroke MRI Protocol....Pages 45-48 Comparison of DWI and CT....Pages 49-53 Characterization of Hyperacute Ischemic Stroke with Stroke MM....Pages 55-61 Thrombolytic Therapy in Stroke....Pages 63-74 Impact of Stroke MRI on Therapeutic Decision Making....Pages 75-81 Alternative and Future Imaging Prospects....Pages 83-90 The Role of Stroke MRI in Clinical Trials....Pages 91-98 Back Matter....Pages 99-119