Stem Cells Heterogeneity in Cancer (Advances in Experimental Medicine and Biology Book 1139)

This book presents a comprehensive discussion on the heterogeneity existing between different types of stem cells within the same tissue, for several types of cancers, e.g. glioblastoma stem cells. Recent developments have revealed completely different roles of distinct stem cells within the same organ.Thus, __Stem Cells Heterogeneity in Cancer__ provides a timely update us on the current information on stem cells heterogeneity in various tissues. It also provides a solid foundation of the history of stem cells from specific tissues and the current applications of this knowledge in regenerative medicine. When taken as a whole, alongside its companion volumes __Stem Cells Heterogeneity – Novel Concepts__, and __Stem Cells Heterogeneity in Different Organs__, these three books present a comprehensive reference on stem cell heterogeneity in various tissues and current and future applications for regenerative medicine. It is essential reading for advanced cell biology students as well as researchers in stem cells and clinicians. Front Matter ....Pages i-xii Multilayered Heterogeneity of Glioblastoma Stem Cells: Biological and Clinical Significance (Daniel V. Brown, Stanley S. Stylli, Andrew H. Kaye, Theo Mantamadiotis)....Pages 1-21 Heterogeneity of Head and Neck Squamous Cell Carcinoma Stem Cells (Xu Qian, Xiaobo Nie, Barbara Wollenberg, Holger Sudhoff, Andreas M. Kaufmann, Andreas E. Albers)....Pages 23-40 Heterogeneity of Small Cell Lung Cancer Stem Cells (D. Prabavathy, Niveditha Ramadoss)....Pages 41-57 Heterogeneity of Hepatic Cancer Stem Cells (Caecilia H. C. Sukowati)....Pages 59-81 Heterogeneity and Plasticity of Breast Cancer Stem Cells (Bárbara Sousa, Ana Sofia Ribeiro, Joana Paredes)....Pages 83-103 Heterogeneity of Melanoma with Stem Cell Properties (Elisabeth A. Seftor, Naira V. Margaryan, Richard E. B. Seftor, Mary J. C. Hendrix)....Pages 105-114 Heterogeneity of Colon Cancer Stem Cells (Akihiro Hirata, Yuichiro Hatano, Masayuki Niwa, Akira Hara, Hiroyuki Tomita)....Pages 115-126 Urothelial Cancer Stem Cell Heterogeneity (Michaela Kripnerova, Hamendra Singh Parmar, Martin Pesta, Michaela Kohoutova, Jitka Kuncova, Karel Drbal et al.)....Pages 127-151 Acute Myeloid Leukemia Stem Cell Heterogeneity and Its Clinical Relevance (Theodoros Karantanos, Richard J. Jones)....Pages 153-169 Contribution of Chronic Myeloid Leukaemia (CML) as a Disease Model to Define and Study Clonal Heterogeneity (Marc G. Berger, Céline Bourgne)....Pages 171-185 The Heterogeneity of Osteosarcoma: The Role Played by Cancer Stem Cells (Kristina Schiavone, Delphine Garnier, Marie-Francoise Heymann, Dominique Heymann)....Pages 187-200 Ovarian Cancer Stem Cell Heterogeneity (Jiri Hatina, Maximilian Boesch, Sieghart Sopper, Michaela Kripnerova, Dominik Wolf, Daniel Reimer et al.)....Pages 201-221 Back Matter ....Pages 223-228 This book presents a comprehensive discussion on the heterogeneity existing between different types of stem cells within the same tissue, for several types of cancers, e.g. glioblastoma stem cells. Recent developments have revealed completely different roles of distinct stem cells within the same organ. Thus, Stem Cells Heterogeneity in Cancer provides a timely update us on the current information on stem cells heterogeneity in various tissues. It also provides a solid foundation of the history of stem cells from specific tissues and the current applications of this knowledge in regenerative medicine. When taken as a whole, alongside its companion volumes Stem Cells Heterogeneity – Novel Concepts , and Stem Cells Heterogeneity in Different Organs , these three books present a comprehensive reference on stem cell heterogeneity in various tissues and current and future applications for regenerative medicine. It is essential reading for advanced cell biology students as well as researchers in stem cells and clinicians.