Specificity in biological interactions : proceedings of a working group at the Pontifical Academy of Sciences, November 9-11, 1983

Proceedings of a Working Group at the Pontifical Academy of Sciences, November 9-11, 1983 Front Matter....Pages I-XXXIV Front Matter....Pages XXXV-XXXV Introductory Remarks. Electrostatics and Specificity in Nucleic Acid Reactions....Pages 1-20 Theoretical Studies of Molecular Recognition and Catalysis by Enzymes....Pages 21-41 Molecular Dynamics of the DNA Double Helix....Pages 43-57 Simulating the Energetics and Dynamics of Enzymatic Reactions....Pages 59-81 Structural Studies of DNA-Protein Interactions....Pages 83-98 Protein-Nucleic Acid Interactions Models and Reality....Pages 99-122 Studying Enzyme-Substrate Interactions by Site-Directed Mutagenesis....Pages 123-132 Sequence Dependence of DNA Conformation, Dynamics and Interactions in Solution....Pages 133-173 Elements of Specific Recognition of Non-Intercalating Ligands in the Interaction with DNA....Pages 175-206 Interactions of Transfer RNAs with their Biological Partners....Pages 207-247 Antibody Structure and Specificity....Pages 249-261 Specificity of Ionophore-Cation Interaction....Pages 263-302 Theoretical Analysis of Factors Responsible for Specificity in Ionophore-Cation Interactions....Pages 303-318