Sleep Apnea: Implications in Cardiovascular and Cerebrovascular Disease, Second Edition, Volume 321 (Lung Biology in Health and Disease)

Since the publication of Sleep Apnea: Diagnosis and Treatment first edition there have been many changes within the field of sleep disorders. Within this text, it will highlight the changes in the field while examining new treatment techniques, new treatment data, and new emerging data that relates to specific disorders. Circadian variations in clock genes : implications for cardiovascular disease / Michael Sole Lower brainstem mechanisms of cardiorespiratory integration / Patrice G. Guyenet Mechanical interactions between the respiratory and circulatory systems / Shelly Magder Alterations in respiratory and cardiac activity during sleep onset / John Trinder Physiological effects of sleep on the cardiovascular system / Richard L. Horner Metabolic effects of normal and disturbed sleep / Naresh Punjabi Oxidative stress, inflammation, and vascular function in sleep apnea / Walter McNicholas Obesity, leptin and sleep apnea / Christopher O'Donnell Influence of sleep apnea on heart rate and blood pressure regulation : implications for hypertension and impaired heart rate variability / Virend Somers Epidemiological evidence for an association between sleep apnea, hypertension and cardiovascular disease / Susan Redline Treatment of hypertension in sleep apnea / Alexander G. Logan Cardiac arrhythmias and sleep apnea / Richard S.T. Leung and Clodagh Ryan Sleep apnea and atherosclerosis / Geraldo Lorenzi-Filho and Luciano Drager Sleep apnea and cerebrovascular disease / Claudio Bassetti Circadian variation in the incidence of cardiovascular and cerebrovascular ischemic events / Apoor Gami Theoretical models of periodic breathing / Michael Khoo Pathophysiological interactions between sleep apnea and congestive heart failure / T. Douglas Bradley, John S. Floras Prevalence and prognostic significance of obstructive and central sleep apnea in heart failure / Paula Lanfranchi Treatment of obstructive and central sleep apnea in patients with heart failure / Matthew T. Naughton and Michael Arzt. Sleep Apnea: Implications in Cardiovascular and Cerebrovascular Disease specifically addresses the cardiovascular and cerebrovascular consequences of sleep apnea and is geared toward a broad readership of physicians that will ultimately aid patients suffering from sleep apnea. The Second Edition ensures that there is a critical synthesis of existin Preface 10 Contributors 14 Contents 18 Chapter 1 22 Chapter 2 36 Chapter 3 61 Chapter 4 82 Chapter 5 98 Chapter 6 114 Chapter 7 131 Chapter 8 144 Chapter 9 162 Chapter 10 184 Chapter 11 201 Chapter 12 213 Chapter 13 240 Chapter 14 258 Chapter 15 282 Chapter 16 296 Chapter 17 323 Chapter 18 358 Chapter 19 372 Index 404 Respiration-synchronous oscillations in sympathetic nerve discharge were described by Adrian and colleagues more than 50 years ago (1); however, despite considerable study by many investigators, the mechanisms responsible for respiratory modulation of autonomic activity remain incompletely understood today.