Skeletal Muscle Plasticity in Health and Disease: From Genes to Whole Muscle (Advances in Muscle Research Book 2)

The ability of striated muscle tissue to adapt to changes in activity or in working conditions is extremely high. In some ways it is comparable to the ability of the brain to learn. The interest in muscle adaptation is increasing in relation to the idea that physical fitness helps in the prevention of disease, may counteract the loss of physical performance and generally improves wellbeing. Plasticity is the word used since the late 1970's to indicate collectively all the processes and mechanisms which form the background of muscle adaptation. This book aims to provide a systematic updating of the available knowledge on molecular and cellular mechanisms, as well as on changes at whole muscle level. The book means to be a guide and a help for people who enter the field as PhD or medical students, but is also a tool for refreshing and updating knowledge for people already active in the field in basic sciences as well as in applied disciplines such as neurology, sports science and rehabilitation. 1.jpg......Page 1 a.pdf......Page 2 Contents......Page 6 Preface......Page 8 Skeletal muscle plasticity -- history, facts and concepts......Page 10 Expression Profiles and Skeletal Muscle Adaptation......Page 37 Striated Muscle Plasticity......Page 63 Signaling pathways, muscle phenotype and nerve activity......Page 98 Activity Dependent Control of NFAT and HDAC in muscle fibres......Page 127 Satellite Cell Function in Skeletal Muscle......Page 142 Plasticity of Excitation-Contraction Coupling in Skeletal Muscle......Page 178 Myofibrillar Protein Composition of Mammalian Muscle Fibers......Page 217 Muscle Architecture and Adaptations to Functional Requirements......Page 269 Responses and Adaptations of skeletal muscle......Page 293 Skeletal Muscle Adaptations to Disease States......Page 319 Index......Page 365 Talks about molecular and cellular mechanisms, as well as on changes at whole muscle level. This book means to be a guide and a help for people who enter the field as PhD or medical students, but is also a tool for people already active in the field in basic sciences as well as in applied disciplines such as neurology and sports science