Signal transduction by G protein-coupled receptors : bioenergetics and G protein activation : proton transfer and GTP synthesis to explain the experimental findings

Front Matter....Pages i-xiv Front Matter....Pages 1-1 Bioenergetics....Pages 3-16 Primary and Secondary Proton Pumps....Pages 17-26 ATP Hydrolysis and Synthesis Mechanisms....Pages 27-39 Front Matter....Pages 41-41 G Protein-Coupled Receptors and G Proteins....Pages 43-62 The (Extended) Ternary Complex Model ([E]TCM) for G Protein Activation....Pages 63-73 Nucleotide Exchange Reactions and G Protein Activation....Pages 75-92 A New Mechanism for G Protein Activation....Pages 93-111 Principles of a New Molecular Mechanism for Signal Transduction....Pages 113-141 Conclusions and Future Perspectives....Pages 143-148 Back Matter....Pages 149-151