Severe Dementia

The later stages of dementia are as important, if not more so, as the earlier stages, since they harbour unique characteristics and events, which profoundly affect the lives of patients and their carers. Severe dementia has not had a high profile in the clinical literature as until recently prognosis was poor and there were few beneficial interventions. With the recent licensing of memantine, clinicians finally have a drug option that will delay disease progression. Severe Dementia is the first book to focus exclusively on severe dementia. It addresses both the clinical features of the disease and the social aspects of care. Introductory chapters on the differential diagnosis, neurochemistry and molecular pathology of severe dementia set the scene for the clinical discussion. Detailed clinical chapters on cognitive function, depression, physical effects, staging and function follow. All therapeutic interventions are then discussed, including memantine, anticholinesterases, neuroleptics and non-pharmacological treatment. The final chapters review the social and economic aspects of dementia care, including family involvement, person-centered care, palliative care, ethics and health economics. Written and edited by experts in geriatric psychiatry and geriatrics, Severe Dementia is of value to all clinicians involved in the management of this complex and vulnerable group of patients. It is also of interest to general practitioners and carers in nursing homes. Assessment And Diagnosis Of Severe Dementia / Paul Newhouse And Joseph Lasek -- Cholinergic And Serotonergic Systems In Severe Dementia / Sally I. Sharp, Paul T. Francis, And Clive G. Ballard -- The Molecular Pathology Of Severe Dementia / Clive Holmes -- Cognitive Functions In Severe Dementia / Judy Saxton And Franc̦ois Boller -- Behavioural And Psychological Symptoms Of Dementia - Agitation / E. Jane Byrne, Deborah Collins, And Alistair Burns -- Depression In Severe Dementia / Kate Bielinski And Brian Lawlor -- Physical Aspects Of Severe Alzheimer's Disease / Bruno Vellas -- Clinical Features Of Severe Dementia : Staging / Barry Reisberg ... [et Al.]. Clinical Features Of Severe Dementia : Function / Serge Gauthier -- Drug Treatment : Memantine / Anton P. Porsteinsson And Pierre N. Tariot -- Drug Treatment : Cholinesterases Inhibitors / Michael Woodward And Howard H. Feldman -- Drug Treatment : Treatment Of Behavioural And Psychological Symptoms Of Dementia With Neuroleptics / Peter Paul De Deyn -- Non-pharmacological Treatment Of Severe Dementia : An Overview / Ross Overshott And Alistair Burns -- Non-pharmacological Treatment Of Severe Dementia : The Seattle Protocols / Rebecca G. Logsdon, Linda Teri, And Sue M. Mccurry. Care By Families For Late Stage Dementia / Steve H. Zarit And Joseph E. Gaugler -- Person-centred Care For People With Severe Dementia / Murna Downs, Neil Small, And Katherine Froggatt -- Palliative Care In Patients With Severe Dementia / Raymond T.c.m. Koopmans, H.roeline W. Pasman, And Jenny T. Van Der Steen -- Narrative Ethics And Ethical Narratives In Dementia / Clive Baldwin -- Health Economics Of Severe Dementia / Anders Wimo And Bengt Winblad. Editors, Alistair Burns, Bengt Winblad. Includes Bibliographical References And Index. Also Available In An Electronic Version. Mode Of Access: World Wide Web. Assessment and diagnosis of severe dementia / Paul Newhouse, Joseph Lasek Cholinergic and serotonergic systems in severe dementia / Sally I. Sharp, Paul T. Francis and Clive Ballard The molecular pathology of severe dementia / Clive Holmes Cognitive functions in severe dementia / Judith Saxton and Franc̦ois Boller Behavioural and psychological symptoms of dementia : agitation / E. Jane Byrne, Deborah Collins and Alistair Burns Depression in severe dementia / Kate Bielinski and Brian Lawlor Physical aspects of severe Alzheimer's disease / Bruno Vellas Clinical features of severe dementia : staging / Barry Reisberg, Jerzy Wegiel, Emile Franssen, Sridhar Kadiyala, Stefanie Auer, Linduïn Souren, Marwan Sabbagh and James Golomb Clinical features of severe dementia : function / Serge Gauthier Drug treatment : memantine / Anton P. Porsteinsson and Pierre N. Tariot Drug treatment : cholinesterase inhibitors / Michael Woodward and Howard H. Feldman Drug treatment : treatment of behavioural and psychological symptoms of dementia with neuroleptics / Peter Paul De Deyn Non-pharmacological treatment of severe dementia : an overview / Ross Overshott and Alistair Burns Non-pharmacological treatment of severe dementia : the Seattle protocols / Rebecca G. Logsdon, Linda Teri and Sue M. McCurry Care by families for late stage dementia / Steve H. Zarit and Joseph E. Gaugler Person-centred care for people with severe dementia / Murna Downs, Neil Small and Katherine Froggatt Palliative care in patients with severe dementia / Raymond T.C.M. Koopmans, H. Roeline W. Pasman and Jenny T. van der Steen Narrative ethics and ethical narratives in dementia / Clive Baldwin Health economics of severe dementia / Anders Wimo and Bengt Winblad. Summarizes current knowledge of pathophysiology and provides a detailed guide to all aspects of the clinical management of these patients. Introductory chapters cover the Differential Diagnosis, Neurochemistry and Molecular Pathology of severe dementia set the scene for the clinical discussion. These are followed by detailed clinical chapters on Cognitive Function, Depression, Physical Effects, Staging and Function. All therapeutic interventions are then discussed, including chapters dedicated to Memantine, Anticholinesterases, Neuroleptics and Nonpharmacological treatment. The final chapters review the social and economic aspects of dementia care, including family involvement, person-centered care, palliative care, ethics and health economics Severe dementia has not been much covered in the clinical literature because until recently, prognosis was very bad and there were few constructive interventions or management tools. This new title provides a state of the art review on the issues of severe dementia, including pathogenesis and neurochemistry Severe Dementia is a clinical text giving clear guidance on the management of all forms of severe dementia. It covers diagnosis, reviews all therapeutic interventions and includes chapters on the ethical, legal and social aspects of care of these patients. When presented with a patient who appears to have moderate to severe cognitive impairment, differential diagnosis is often difficult.