Selective Sentinel Lymphadenectomy for Human Solid Cancer (Cancer Treatment and Research Book 127)

Lymph Node (ln) Status Is The Most Important Prognostic Indicator For The Clinical Outcome Of Patients In Human Solid Cancer. Recent Developments In Sentinel Lymph Node (sln) Concept And Technology Have Resulted In The Application Of This Revolutionary Approach To Determine If Cancer Has Metastasized. The Underlying Thesis In Solid Cancer Biology Is That Metastasis Generally Starts In An Orderly Progression, Often Spreading Through The Lymphatic Channels To The Sln. Thus, The Logical Approach Is To Harvest That Specific Sln For Thorough Analysis. The Mist Exciting Possibility Of Selective Sentinel Lymphadenectomy (ssl) Is That It Will Lead To Early Diagnosis Of Micrometastasis In Regional Lns. New Molecular And Genetic Tools May Be Used To Dissect The Mechanisms Of Lymphatic And Hemotogenous Routes Of Metastasis. If Such Mechanisms Can Be Understood, New Therapeutic Advances May Be Developed To Prevent The Process Of Micrometastasis. The Development Of Lymphatic Mapping And Sentinel Lymphadenectomy: A Historical Perspective -- Role Of Lymphoscintigraphy For Selective Sentinel Lymphadenectomy -- Selective Sentinel Lymphadenectomy Of Malignant Melanoma, Merkel Cell Carcinoma, And Squamous Cell Carcinoma: Selective Sentinal Lymphadenectomy For Cutaneous Malignancy -- Selective Sentinel Lymphadenectomy For Breast Cancer -- Sentinel Lymph Node Mapping In Colon And Rectal Cancer: It's Impact On Staging, Limitations, And Pitfalls -- Sentinel Lymph Node Mapping In Esophageal And Gastric Cancer -- Sentinel Lymph Node Mapping In Lung Cancer -- Lymphatic Mapping And Sentinel Lymphadenectomy In Urology -- Selective Sentinel Lymphadenectomy For Gynecologic Cancer -- Selective Sentinel Lymphadenectomy For Head And Neck Squamous Cell Carcinoma -- Accurate Evaluation Of Nodal Tissues For The Presence Of Tumor Is Central To The Sentinel Mode Approach -- Molecular Diagnosis Of Micrometastasis In The Sentinel Lymph Node -- Credentialing Of Nuclear Medicine Physicians, Surgeons, And Pathologists As A Multidisciplinary Team For Selective Sentinel Lumphadenectomy -- Selective Sentinel Lymphadenectomy: Progress To Date And Prespects For The Future. Edited By Stanley P.l. Leong, Yuko Kitagawa, Masaki Kitajima. Includes Bibliographical References And Index. System Requirements: Cd-rom Drive. asd for aek fc original21.jpg......Page 1 front-matter.pdf......Page 2 1.pdf......Page 22 2.pdf......Page 36 3.pdf......Page 60 4.pdf......Page 98 5.pdf......Page 126 6.pdf......Page 144 7.pdf......Page 161 8.pdf......Page 169 9.pdf......Page 185 10.pdf......Page 204 11.pdf......Page 224 12.pdf......Page 238 13.pdf......Page 270 14.pdf......Page 285 back-matter.pdf......Page 304 In human solid cancer, the lymph node (LN) status is the most important prognostic indicator for the clinical outcome of patients. Various developments in the sentinel lymph node (SLN) concept and technology have resulted in the application of this revolutionary approach to define the draining or SLN to which the cancer may have metastasized First book to apply the concept of SSL to the majority of human cancers Revolutionary new concept that might significantly transform surgical cancer treatment Focuses on cancer metastasis and explores the biological frontier of micro metastasis Includes illustrations by experts in the field on how to successfully perform SSL Intraoperative lymphatic mapping and sentinel lymphadenectomy (ILM/SL) is a novel surgical technique that has substantially impacted on the way cutaneous melanoma and breast cancer are now being staged and managed.